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Extracellular vesicle miRNAs as potential early biomarkers for acute myocardial infarction

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study sought to determine the potential of extracellular vesicle (EV) microRNAs (miRNAs) to serve as early diagnostic biomarkers for AMI.

17 Jan 2025

SOX9 overexpression protects against lipid accumulation in MASH via AMPK activation

The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in organ development.

17 Jan 2025

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Bone loss resulting from trauma, fractures, or disease presents a major global health challenge, often leading to long-term disability.

17 Jan 2025

Over 500 European patients diagnosed through groundbreaking genetic research

More than 500 European patients with unknown conditions have received a diagnosis through new genetic research.

17 Jan 2025

New research identifies metabolic targets to combat antibiotic-resistant bacterial infections

Targeting unique metabolic pathways in pathogens offers a novel approach to precision antibiotics, addressing the growing challenge of antimicrobial resistance.

17 Jan 2025

New approach shows promise in fighting multiple cancers

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target some of these pro-tumor actions are effective in a number of cancers, but only for some patients; in others, these treatments have little effect.

17 Jan 2025

Bidirectional movement drives DNA loop formation

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one direction only. The discovery, which is published in Cell, is key to understanding how these motors shape our genome and regulate our genes.

17 Jan 2025

Immune cells orchestrate glucagon production during fasting

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role.

17 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.

16 Jan 2025

Unveiling the genetic roots of bicuspid aortic valve

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, according to a new study led by UTHealth Houston researchers.

16 Jan 2025

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

15 Jan 2025

Scientists unveil global patterns in early-life gut microbial evolution

Scientists reveal that early-life gut microbiome development follows universal patterns, paving the way for new benchmarks in child health assessments.

15 Jan 2025

Hormonal shifts in menopause redefine women’s microbiome and risks

Research explores how menopause-induced hormonal shifts affect the microbiome, influencing oral, gut, and urogenital health, and highlights the potential of personalized interventions to enhance well-being.

15 Jan 2025

Researchers identify a natural defense against blood vessel inflammation and atherosclerosis

Research reveals IGFBP6's role in suppressing vascular inflammation and atherosclerosis, suggesting it as a novel target for cardiovascular disease therapy.

15 Jan 2025

New genetic risk factors for depression identified across global populations

New genetic risk factors for depression have been identified across all major global populations for the first time, allowing scientists to predict risk of depression regardless of ethnicity.

15 Jan 2025

Study links epigenetic mechanism to placental blood vessel development

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University discovered that the correct development of functioning blood vessels in the mouse placenta is controlled epigenetically: One of the enzymes that modify gene activity using methyl groups is responsible.

15 Jan 2025

Pancreatic cancer insights: How pORG classifications predict survival and guide treatment

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

15 Jan 2025

Enhanc3D Genomics launches suite of 3D multi-omics solutions to accelerate drug development

Enhanc3D Genomics (‘Enhanced’), an innovator in 3D genomics technology, today announced the launch of a suite of integrated multi-omics solutions to accelerate and improve the precision of drug discovery.

From Enhanc3D Genomics 15 Jan 2025

Genes News and Research

Extracellular vesicle miRNAs as potential early biomarkers for acute myocardial infarction

SOX9 overexpression protects against lipid accumulation in MASH via AMPK activation

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Over 500 European patients diagnosed through groundbreaking genetic research

New research identifies metabolic targets to combat antibiotic-resistant bacterial infections

New approach shows promise in fighting multiple cancers

Bidirectional movement drives DNA loop formation

Immune cells orchestrate glucagon production during fasting

Scientists discover new mechanism behind Huntington’s disease brain cell death

Study unveils role of TLE6 in male sperm development

Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

Unveiling the genetic roots of bicuspid aortic valve

New target identified for potential colorectal cancer treatment

Scientists unveil global patterns in early-life gut microbial evolution

Hormonal shifts in menopause redefine women’s microbiome and risks

Researchers identify a natural defense against blood vessel inflammation and atherosclerosis

New genetic risk factors for depression identified across global populations

Study links epigenetic mechanism to placental blood vessel development

Pancreatic cancer insights: How pORG classifications predict survival and guide treatment

Enhanc3D Genomics launches suite of 3D multi-omics solutions to accelerate drug development

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