Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Dysregulated retroelements associated with autoimmunity in COVID-19

Researchers investigate potential interactions between retro-elements shared between the human and coronavirus genomes.

12 Apr 2022

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Anosmia, the loss of smell, is a frequent and often long-term symptom associated with COVID-19 that can severely burden a person's quality of life, making it extremely difficult to taste foods, detect airborne hazards in the environment and carry out other functions dependent on the sense.

11 Apr 2022

Millions of people face a postcode lottery to access fertility freezing treatments

Depending on where some people live in the UK could mean they are denied an NHS treatment which helps patients with medical needs, such as cancer and transgender issues, become parents in the future.

11 Apr 2022

International study offers insight into occurrence of acute myocarditis during COVID-19 hospitalization

Acute myocarditis, inflammation of the heart muscle typically triggered by a virus, occurred in about two out of every 1,000 people hospitalized with COVID-19, and was associated with more severe illness and complications in people with COVID-19, especially among people who also had pneumonia, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

11 Apr 2022

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Adding the immunotherapy drug nivolumab to chemotherapy before surgery (neoadjuvant) for patients with operable non-small cell lung cancer (NSCLC) — the leading cause of cancer deaths worldwide — reduced the risk of recurrence of the cancer or death by more than one-third, according to results from the phase III CheckMate-816 trial.

11 Apr 2022

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Researchers tested whether a subunit vaccine could generate mucosal immunity in mice and prevent SARS-CoV-2 infection and related pathology.

11 Apr 2022

Vaccine-induced blood clots may be the result of genetics, study finds

The rare blood clot side-effect associated with some COVID-19 vaccines could be the result of genetics, new research has found, paving the way for a potential genetic screening test.

11 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

AI model uses electronic health records to identify people at high risk for pancreatic cancer

An artificial intelligence (AI) model trained using sequential health information derived from electronic health records identified a subset of individuals with a 25-fold risk of developing pancreatic cancer within three to 36 months, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

Transcriptional reprogramming of monocytes in COVID-19

In a recent study posted to the bioRxiv* server, researchers examined the functionality of cluster of differentiation 14-positive (CD14+) monocytes in patients with mild or moderate coronavirus disease 2019 (COVID-19).

7 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Study captures the immune effect of COVID-19 vaccine in patients with multiple myeloma

Most immunocompromised people with a blood cancer called multiple myeloma benefited from a third dose of COVID-19 vaccines, a promising sign after it was shown that two doses tended to not be sufficient for them.

6 Apr 2022

COVID-19 can cause inflammation and bleeding in the brain

A new study published in Nature Communications investigates SARS-CoV-2-infected non-human primates (NHPs) to understand the neurological symptoms associated with "long COVID."

6 Apr 2022

Study provides key insights into the spread of Rocky Mountain spotted fever

Findings from a new study are providing important insights into the spread of Rocky Mountain spotted fever, which is transmitted from dogs to people through ticks. The new data are being used to create models that could help predict, and possibly prevent, future outbreaks.

5 Apr 2022

Pathology News and Research

Further Reading

Dysregulated retroelements associated with autoimmunity in COVID-19

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Millions of people face a postcode lottery to access fertility freezing treatments

International study offers insight into occurrence of acute myocarditis during COVID-19 hospitalization

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Vaccine-induced blood clots may be the result of genetics, study finds

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

AI model uses electronic health records to identify people at high risk for pancreatic cancer

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Transcriptional reprogramming of monocytes in COVID-19

Researchers discover over 40 new genetic markers for Alzheimer’s disease

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Study captures the immune effect of COVID-19 vaccine in patients with multiple myeloma

COVID-19 can cause inflammation and bleeding in the brain

Study provides key insights into the spread of Rocky Mountain spotted fever

New findings cement the lymphatic system’s role in heart repair

Gut bacterium may be an important factor in resistance to antihypertensive medications

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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