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TCU, UNTHSC sign MOU to create new MD school in Fort Worth

Texas Christian University and the University of North Texas Health Science Center have entered into a memorandum of understanding to create a new MD school in Fort Worth. The school, planning to accept its first class in 2018, will be among the leading institutions in the nation in providing a team-oriented educational approach that benefits patients and shapes the future practice and business of medicine.

7 Jul 2015

Expectant management remains underused for men with low-risk prostate cancer

Monitoring men with very low- and low-risk prostate cancers using watchful waiting or active surveillance, called expectant management, is a useful approach for a large number of men with localized tumors and could spare them the debilitating side effects of aggressive treatments that are too often unnecessarily used in this patient population, a UCLA review of common practices in prostate cancer has found.

7 Jul 2015

LSD1 enzyme turns off genes needed to maintain cancer stem cell properties in glioblastoma

Cancer's ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem cells retain this property while the bulk of a tumor's cells do not remains largely unknown. Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes -- chemical modifications cells use to control which genes are turned on or off.

7 Jul 2015

Dental pulp stem cell transplants can contribute to peripheral nerve regeneration

Peripheral nerve injuries often are caused by trauma or surgical complications and can result in considerable disabilities. Regeneration of peripheral nerves can be accomplished effectively using autologous (self-donated) nerve grafts, but that procedure may sacrifice a functional nerve and cause loss of sensation in another part of the patient's body.

7 Jul 2015

AOSSM to present awards and grants to encourage cutting-edge research in orthopaedic sports medicine

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine will present ten research awards and seven grants during its Annual Meeting, July 9-12 in Orlando, FL.

7 Jul 2015

New portable system can produce life-saving NO from air by means of electrical spark

Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy's high price.

7 Jul 2015

New research suggests that Bcl-Rambo protein can protect against heart failure

A protein dubbed 'Bcl-Rambo' can protect against heart failure, suggests new research from King's College London and funded by the British Heart Foundation.

7 Jul 2015

University of Adelaide research may lead to new treatments for transplant patients

Researchers at the University of Adelaide have discovered a new method for culturing stem cells which sees the highly therapeutic cells grow faster and stronger.

7 Jul 2015

Pazopanib improves survival in soft tissue sarcoma patients without impairment of health-related quality of life

Results of EORTC trial 62072 appearing in Cancer show that in patients with soft tissue sarcoma, whose disease had progressed during or after prior chemotherapy, pazopanib improved progression-free survival but did not change health-related quality of life. This observed improvement in progression-free survival without impairment of health-related quality of life was considered a meaningful result.

7 Jul 2015

Breakthrough discovery could help young girls suffering from rare form of epilepsy

An international team, led by a University of Adelaide genetics expert, has made a breakthrough discovery which is expected to help thousands of young girls worldwide who are suffering from a rare yet debilitating form of epilepsy.

7 Jul 2015

Researchers analyze cardiometabolic benefits of exercise

Everyone knows that exercise generally helps the cardiovascular system, but much remains unknown about how the benefits arise, and what to expect in different people who exercise to improve their health. To gain a more precise understanding of how exercise improves health and whom it helps most, researchers analyzed the results of 160 randomized clinical trials with nearly 7,500 participants.

3 Jul 2015

Two new studies show that fecal transplantation may help fight against ulcerative colitis

Two new studies led by researchers from the Farncombe Family Digestive Health Research Institute at McMaster University show that transplantation of fecal matter may be a useful tool in the fight against ulcerative colitis (UC).

3 Jul 2015

New AHA/ASA guidelines recommend stent retrievers to treat strokes in selected patients

New devices called stent retrievers are enabling physicians to benefit selected patients who suffer strokes caused by blood clots. The devices effectively stop strokes in their tracks.

3 Jul 2015

Gene therapy improves lung function in patients with cystic fibrosis

Gene therapy was shown to provide significant benefits for patients with cystic fibrosis in a recent clinical study published in The Lancet Respiratory Medicine journal.

3 Jul 2015

WATCHMAN Device helps reduce stroke risk, stop use of blood thinners in patients with atrial fibrillation

MedStar Heart & Vascular Institute now offers patients with irregular heart rhythm a minimally invasive option to reduce the risk of stroke, as well as enable stopping long-term use of blood thinning medication. Physicians at MedStar Heart at MedStar Washington Hospital Center were the first in the Washington metropolitan region to successfully implant the WATCHMAN Device on June 16 in two patients with atrial fibrillation (A-fib).

3 Jul 2015

Gene therapy for cystic fibrosis shows significant benefit in lung function

For the first time gene therapy for cystic fibrosis has shown a significant benefit in lung function compared with placebo, in a phase 2 randomised trial published in The Lancet Respiratory Medicine journal. The technique replaces the defective gene response for cystic fibrosis by using inhaled molecules of DNA to deliver a normal working copy of the gene to lung cells.

3 Jul 2015

Boehringer Ingelheim’s Spiolto Respimat approved for COPD treatment in first European countries

Boehringer Ingelheim today announced regulatory authority approvals for Spiolto Respimat (tiotropium/olodaterol) in first European countries. Spiolto Respimat is a once-daily maintenance treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD).

3 Jul 2015

Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Retinoblastoma protein RB1, which is named after a form of pediatric tumor of the eye, is among the most common genetically regulated cellular proteins to malfunction in human cancer. RB1 was also the first tumor suppressor gene to be identified and its modes of inactivation in retinoblastoma tumors provided the basis for the ground-breaking two-hit hypothesis by the geneticist Alfred G. Knudson in the 70s, according to which cancer is due to the accumulation of multiple 'hits' or mutations in certain genes.

3 Jul 2015

Scientists to discuss the possibility of predicting evolution at scientific conference in Portugal

Is it possible to predict the evolution of the influenza virus? Or how rapidly bacteria evolve resistance to antibiotics? Or even how cancer cells spread inside a human being? These are some of the main topics of discussion that bring together renowned scientists from all over the world at the scientific conference "Forecasting evolution?" held at the Calouste Gulbenkian Foundation (FCG; Portugal) from 8th to 11th July.

3 Jul 2015

Afamelanotide treatment improves quality of life in people with erythropoietic protoporphyria

A novel synthetic hormone that makes certain skin cells produce more melanin significantly increases pain-free sun exposure in people with erythropoietic protoporphyria, a rare, genetic disorder resulting in excruciating pain within minutes of sun exposure.

3 Jul 2015

Therapy News and Research

TCU, UNTHSC sign MOU to create new MD school in Fort Worth

Expectant management remains underused for men with low-risk prostate cancer

LSD1 enzyme turns off genes needed to maintain cancer stem cell properties in glioblastoma

Dental pulp stem cell transplants can contribute to peripheral nerve regeneration

AOSSM to present awards and grants to encourage cutting-edge research in orthopaedic sports medicine

New portable system can produce life-saving NO from air by means of electrical spark

New research suggests that Bcl-Rambo protein can protect against heart failure

University of Adelaide research may lead to new treatments for transplant patients

Pazopanib improves survival in soft tissue sarcoma patients without impairment of health-related quality of life

Breakthrough discovery could help young girls suffering from rare form of epilepsy

Researchers analyze cardiometabolic benefits of exercise

Two new studies show that fecal transplantation may help fight against ulcerative colitis

New AHA/ASA guidelines recommend stent retrievers to treat strokes in selected patients

Gene therapy improves lung function in patients with cystic fibrosis

WATCHMAN Device helps reduce stroke risk, stop use of blood thinners in patients with atrial fibrillation

Gene therapy for cystic fibrosis shows significant benefit in lung function

Boehringer Ingelheim’s Spiolto Respimat approved for COPD treatment in first European countries

Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Scientists to discuss the possibility of predicting evolution at scientific conference in Portugal

Afamelanotide treatment improves quality of life in people with erythropoietic protoporphyria

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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