Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Janssen reports positive pivotal Phase 2 study data of siltuximab for Multicentric Castleman's Disease

Janssen Research & Development, LLC today announced positive results from a pivotal Phase 2 global registration study (MCD2001) suggesting siltuximab, an investigational compound, along with best supportive care, exhibited statistically significant efficacy and a tolerable safety profile compared with placebo and BSC in treating patients with the rare disorder Multicentric Castleman's Disease who are HIV-negative and human herpes virus 8-negative.

8 Dec 2013

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain. Drug testing should therefore be conducted with human nerve cells, conclude the scientists.

6 Dec 2013

Training advised to plug lung cancer care gaps

Guideline-consistent care for patients with suspected lung cancer with mediastinal lymphadenopathy without distant metastases varies by region and physician characteristics, say researchers.

5 Dec 2013

MR-guided ultrasound may offer safe and effective treatment for breast cancer

A technique that uses focused ultrasound under magnetic resonance guidance to heat and destroy tumors may offer a safe and effective treatment for breast cancer, according to research being presented today at the annual meeting of the Radiological Society of North America.

4 Dec 2013

Presence of ERG protein in biopsied prostate tissue increases likelihood of cancer development

Researchers from Weill Cornell Medical College have shown that the presence of a particular protein in biopsied prostate tissue substantially increases the likelihood that cancer will develop in that organ. The discovery will likely help physicians decide how closely to monitor men potentially at risk for the cancer -- among the most confusing and controversial dilemmas in health care.

4 Dec 2013

Study shows that DBT increases cancer detection, reduces recall rates

Researchers have found that digital breast tomosynthesis (DBT) led to reduced recall rates and an increase in cancer detection in a large breast cancer screening program.

3 Dec 2013

Digital breast tomosynthesis reduces recall rates and increases cancer detection

Researchers have found that digital breast tomosynthesis (DBT) led to reduced recall rates and an increase in cancer detection in a large breast cancer screening program. The results of this study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2013

Reimbursement cuts for image-guided breast biopsies may reduce women's access to mammography

Drastic reimbursement cuts for image-guided breast biopsies, and other medical imaging techniques in the 2014 Medicare Fee Schedule Final Rule, may further reduce women's access to mammography and other breast cancer services. The Centers for Medicare and Medicaid Services directly cut imaging reimbursement every year since 2007. This, along with 12 Medicare imaging cuts in the last six years due to legislation, increasingly threatens patient care.

3 Dec 2013

3D mammography identifies 22% more breast cancers than traditional mammography

Compared to traditional mammography, 3D mammography—known as digital breast tomosynthesis—found 22 percent more breast cancers and led to fewer call backs in a large screening study at the Hospital of the University of Pennsylvania, researchers reported today at the annual meeting of the Radiological Society of North America.

3 Dec 2013

Virginia Mason first to use non-invasive FibroScan technology to evaluate liver diseases

Virginia Mason today becomes the first in the Pacific Northwest to use non-invasive FibroScan technology to evaluate disease stage in patients diagnosed with liver ailments.

3 Dec 2013

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that it has initiated a Phase 2, randomized, double-blind, placebo-controlled study evaluating orBec (oral beclomethasone 17,21-dipropionate or BDP) as a treatment for the gastrointestinal manifestations of chronic Graft-versus-Host disease.

2 Dec 2013

New biomarkers to improve diagnostics of prostate cancer

New biomarkers will improve diagnostics of endemic diseases in future, such as prostate cancer. Their mission: to recognize the tumor earlier and classify it more precisely - thereby helping avoid unnecessary operations.

2 Dec 2013

Cedars-Sinai researchers design new procedure to treat stem cell-related corneal blindness

Researchers in the Cedars-Sinai Regenerative Medicine Institute have designed and tested a novel, minute-long procedure to prepare human amniotic membrane for use as a scaffold for specialized stem cells that may be used to treat some corneal diseases.

27 Nov 2013

CRI researcher receives grant from DIPG to research on pediatric brain tumors

Javad Nazarian, PhD, a researcher with Children's Research Institute (CRI) at Children's National, is the recipient of a $99,979 grant from the DIPG Collaborative for his proposal entitled, "Comparative Proteomic and RNA Sequencing of DIPGs."

27 Nov 2013

Genetic variation linked to increased levels of triglycerides associated with heart disorders

Researchers at Weill Cornell Medical College have found that a genetic variation that is linked to increased levels of triglycerides -- fats in the blood associated with disorders such as heart disease, type 2 diabetes, obesity and stroke -- is far more common than previously believed and disproportionally affects people of African ancestry.

26 Nov 2013

First molecular test developed to detect eosinophilic esophagitis

Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis, a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago.

22 Nov 2013

Research: New drugs show ability to rapidly shrink melanoma tumors

Melanoma is the deadliest form of skin cancer, killing more than 8,000 in the U.S. each year. Approximately 40 percent of advanced melanoma tumors are driven to grow by the presence of mutations in a gene known as the BRAF gene.

21 Nov 2013

Hologic to highlight groundbreaking imaging products at RSNA 2013

Hologic, Inc., a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems and surgical products, with an emphasis on serving the healthcare needs of women, today announced the groundbreaking imaging products it will highlight at the 99th Scientific Assembly and Annual Meeting of the Radiological Society of North America at McCormick Place, Chicago from December 1st through 5th.

From Hologic, Inc. 21 Nov 2013

Weill Cornell Medical College receives grant to support research efforts designed to end women's cancers

MasterCard today announced a $500,000 grant to Weill Cornell Medical College to support research efforts designed to end women's cancers.

19 Nov 2013

Breast biopsies can affect short-term quality-of-life in younger patients

Breast biopsies can adversely affect short-term quality-of-life, and the effects are more pronounced in younger patients, according to a new study published online in the journal Radiology.

19 Nov 2013

Biopsy News and Research

Further Reading

Janssen reports positive pivotal Phase 2 study data of siltuximab for Multicentric Castleman's Disease

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Training advised to plug lung cancer care gaps

MR-guided ultrasound may offer safe and effective treatment for breast cancer

Presence of ERG protein in biopsied prostate tissue increases likelihood of cancer development

Study shows that DBT increases cancer detection, reduces recall rates

Digital breast tomosynthesis reduces recall rates and increases cancer detection

Reimbursement cuts for image-guided breast biopsies may reduce women's access to mammography

3D mammography identifies 22% more breast cancers than traditional mammography

Virginia Mason first to use non-invasive FibroScan technology to evaluate liver diseases

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

New biomarkers to improve diagnostics of prostate cancer

Cedars-Sinai researchers design new procedure to treat stem cell-related corneal blindness

CRI researcher receives grant from DIPG to research on pediatric brain tumors

Genetic variation linked to increased levels of triglycerides associated with heart disorders

First molecular test developed to detect eosinophilic esophagitis

Research: New drugs show ability to rapidly shrink melanoma tumors

Hologic to highlight groundbreaking imaging products at RSNA 2013

Weill Cornell Medical College receives grant to support research efforts designed to end women's cancers

Breast biopsies can affect short-term quality-of-life in younger patients

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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