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Rare immune mutation unlocks universal antiviral protection

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower-the ability to fight off all viruses.

14 Aug 2025

PSMA PET/CT improves outcomes for men with recurrent prostate cancer

A new study from Denmark shows for the first time that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not.

14 Aug 2025

New study explains why neuroblastoma returns years later

Cancer is the leading cause of disease-related death in childhood. This is in part due to cancer-associated genes called oncogenes that can be found far from chromosomes in cell nuclei on ring-shaped DNA inside tumor cells.

14 Aug 2025

New drug discovery platform aims to deliver first-in-class therapies

65LAB has awarded US$1.5 million (approx. S$1.9 million) to Professor Enrico Petretto to advance a breakthrough drug discovery platform developed at Duke-NUS Medical School. The project aims to deliver first-in-class antifibrotic therapies for lung and kidney diseases-conditions that currently have no effective treatment.

14 Aug 2025

Griffith University launches groundbreaking treatment trial for spinal cord injury

A Phase 1 human clinical trial to treat chronic spinal cord injury, the first of its kind in the world, has commenced to test the efficacy and safety of a revolutionary new treatment using nasal cells.

13 Aug 2025

New computational tool enhances CAR T cell therapy for hard-to-treat cancers

A computational approach by St. Jude Children's Research Hospital scientists promises to make designing T cell-based immunotherapies that target two cancer-related antigens at the same time far easier and faster.

13 Aug 2025

Leading organizations announce research initiative to uncover why ALS affects high-performing populations

Answer ALS, in collaboration with ALS Therapy Development Institute (ALS TDI) and Augie's Quest, today announced plans to launch Champion Insights, an ambitious research initiative designed to uncover critical genetic and metabolic mechanisms that may explain the significantly higher incidence of amyotrophic lateral sclerosis (ALS) among endurance athletes, military service members, and potentially other high-performing populations.

13 Aug 2025

AI-powered virtual MRI imaging enables safer and more accurate tumor detection

During magnetic resonance imaging (MRI) procedures, contrast agents, such as the rare metal gadolinium, can pose potential health risks.

13 Aug 2025

Understanding opioid safety and overdose prevention for older adults

With increasing age, older adults are more likely to encounter health conditions and injuries that require opioid therapy for pain relief.

13 Aug 2025

New drug-releasing system eliminates tumors in 82% of high-risk bladder cancer patients

A new drug-releasing system, TAR-200, eliminated tumors in 82% of patients in a phase 2 clinical trial for individuals with high-risk non-muscle-invasive bladder cancer whose cancer had previously resisted treatment.

13 Aug 2025

New compound shows promise against aromatase inhibitor-resistant breast cancer

A new research paper was published in Volume 16 of Oncotarget on July 29, 2025, titled "PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion."

13 Aug 2025

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

Late nights, alcohol, and smoking on weekends may be doing more than disrupting your Monday mornings, they could be triggering a newly identified sleep health concern known as 'social apnea', warn researchers from Flinders University.

13 Aug 2025

Conch shell blowing lowers apnea events during REM sleep

Shankh blowing shows promise in alleviating sleep apnea, with significant improvements in sleep quality and reductions in daytime sleepiness after six months.

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

New research explores foot positioning to treat knee osteoarthritis

Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an uncurable disease in which the cartilage cushion inside a joint breaks down.

13 Aug 2025

Study supports pre-surgery use of GLP-1 RAs for weight reduction

Overweight patients waiting for operations could safely use a particular type of weight-loss treatment to reduce the risk of surgical complications linked to their obesity, a new study reveals.

12 Aug 2025

Lifestyle interventions key to closing life expectancy gap in mental illness

Mental health services must urgently increase investment in lifestyle interventions to improve care and help close the 15-year life expectancy gap faced by people with mental illness, a new Lancet Psychiatry Commission report warns.

12 Aug 2025

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

12 Aug 2025

Light-activated therapy boosts effectiveness of antifungal drugs against Candida albicans

Researchers at the Optics and Photonics Research Center (CePOF) have succeeded in increasing the susceptibility of the fungus Candida albicans to drug treatment through light-activated therapy.

12 Aug 2025

New engineered molecule shows promise as rapid antidote for carbon monoxide poisoning

University of Maryland School of Medicine (UMSOM) researchers, along with their colleagues, engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested, according to a new study published in the journal PNAS.

12 Aug 2025

Therapy News and Research

Rare immune mutation unlocks universal antiviral protection

PSMA PET/CT improves outcomes for men with recurrent prostate cancer

New study explains why neuroblastoma returns years later

New drug discovery platform aims to deliver first-in-class therapies

Griffith University launches groundbreaking treatment trial for spinal cord injury

New computational tool enhances CAR T cell therapy for hard-to-treat cancers

Leading organizations announce research initiative to uncover why ALS affects high-performing populations

AI-powered virtual MRI imaging enables safer and more accurate tumor detection

Understanding opioid safety and overdose prevention for older adults

New drug-releasing system eliminates tumors in 82% of high-risk bladder cancer patients

New compound shows promise against aromatase inhibitor-resistant breast cancer

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

Conch shell blowing lowers apnea events during REM sleep

mRNA vaccine shows potent efficacy in gastric cancer

New research explores foot positioning to treat knee osteoarthritis

Study supports pre-surgery use of GLP-1 RAs for weight reduction

Lifestyle interventions key to closing life expectancy gap in mental illness

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

Light-activated therapy boosts effectiveness of antifungal drugs against Candida albicans

New engineered molecule shows promise as rapid antidote for carbon monoxide poisoning

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