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Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Itch was actually defined by a German physician more than 350 years ago. His name was Samuel Hafenreffer. He defined itch as an unpleasant sensation that makes people want to scratch. You probably think this is a very simple definition but itch is really a very complex sensory modality.

21 Jan 2013

G-quadruplexes also exist within the human genome

In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving 'double helix' DNA structure - the chemical code for all life.

21 Jan 2013

Scientists to investigate how cancer cells hide to avoid chemotherapy drugs

Scientists hope to improve leukaemia treatment by investigating how cancer cells use 'hiding places' in the body to avoid chemotherapy drugs.

17 Jan 2013

New hope for people with sound-induced deafness

Preliminary results from a study in mice suggest it may be possible to regenerate cochlear hair cells that have been damaged due to excessive noise exposure.

15 Jan 2013

TSRI chemists develop new cell-marking method

Chemists at The Scripps Research Institute (TSRI) have found an easier way to perform one of the most fundamental tasks in molecular biology. Their new method allows scientists to add a marker to certain cells, so that these cells may be easily located and/or selected out from a larger cell population.

10 Jan 2013

Link between Parkinson's and benomyl

For several years, neurologists at UCLA have been building a case that a link exists between pesticides and Parkinson's disease. To date, paraquat, maneb and ziram - common chemicals sprayed in California's Central Valley and elsewhere - have been tied to increases in the disease, not only among farmworkers but in individuals who simply lived or worked near fields and likely inhaled drifting particles.

6 Jan 2013

ParoChip can allow dentists to quickly detect and analyze periodontitis pathogens

Bleeding gums during tooth brushing or when biting into an apple could be an indication of periodontitis, an inflammatory disease of the tissues that surround and support the teeth. Bacterial plaque attacks the bone, meaning teeth can loosen over time and in the worst case even fall out, as they are left without a solid foundation to hold them in place.

4 Jan 2013

Whole Genome Mapping and NGS deliver high-quality reference genome of domestic goat

OpGen, Inc. today announced its ARGUS Whole Genome Mapping System technology was used in combination with next-generation sequencing (NGS) to produce the first, high-quality reference genome of the domestic goat.

26 Dec 2012

UV nail lamp use not associated with skin cancer risk

Research shows that artificial ultraviolet (UV) nail lamps do not significantly increase the risk for developing keratinocyte carcinoma.

22 Dec 2012

Lapatinib benefits found for HER2-positive early-stage patients

Women with early-stage, HER2-positive breast cancer who are unable to use trastuzumab may benefit from adjuvant lapatinib treatment, suggest phase III trial findings published in Lancet Oncology.

17 Dec 2012

NeoGenomics launches FISH assay for surveillance of patients with Barrett's Esophagus

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today it has validated and launched a laboratory developed Fluorescent in Situ Hybridization assay for the surveillance of patients with Barrett's Esophagus.

17 Dec 2012

Immunohistochemistry reliable in identifying ALK rearrangement: Study

Favorable results have led to crizotinib gaining approval for the treatment of advanced stage ALK-positive non-small cell lung cancer (NSCLC) in Japan, the United States, Canada, and several other countries in Europe and Asia.

17 Dec 2012

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

Every time a human or bacterial cell divides it first must copy its DNA. Specialized proteins unzip the intertwined DNA strands while others follow and build new strands, using the originals as templates. Whenever these proteins encounter a break - and there are many - they stop and retreat, allowing a new cast of molecular players to enter the scene.

14 Dec 2012

New diagnostic assay for screening ALK fusions in non-small cell lung carcinoma

Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients are highly responsive to ALK-specific kinase inhibitors such as crizotinib.

From NanoString Technologies 13 Dec 2012

Using Nanoparticles to Target Cancer

An interview with John Stroh, discussing the development of nanoparticles that can target and treat cancer, without damaging nearby tissues.

6 Dec 2012

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

Scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they turned to the zebrafish, which is transparent in the early stages of its life. The researchers developed a transgenic variety, the "MitoFish," that enables them to see - within individual neurons of living animals - how brain diseases disturb the transport of mitochondria, the power plants of the cell.

6 Dec 2012

Paper reveals how 'kinase' is distributed across membranes

Using a super-resolution fluorescent microscope, Australian medical scientists are a step closer to understanding why and how human immune cells decide to activate or not, thus enabling or preventing disease taking hold in the body.

5 Dec 2012

New study on mice could open door to methods of regulating cell proliferation in humans

A newly-engineered strain of mice whose dividing cells express a fluorescent protein could open the door to new methods of regulating cell proliferation in humans.

1 Dec 2012

Scientists identify two genes involved in establishing neuronal circuits required for breathing

Scientists at NYU Langone Medical Center have identified two genes involved in establishing the neuronal circuits required for breathing. They report their findings in a study published in the December issue of Nature Neuroscience.

30 Nov 2012

Two Sanford-Burnham projects win International Space Station Research Competition

Sanford-Burnham Medical Research Institute (Sanford-Burnham) today announced that two of the Institute's research teams have won Space Florida's International Space Station (ISS) Research Competition. Eight teams were selected from a pool of international applicants to send experiments to space in late 2013.

30 Nov 2012

Fluorescence News and Research

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

G-quadruplexes also exist within the human genome

Scientists to investigate how cancer cells hide to avoid chemotherapy drugs

New hope for people with sound-induced deafness

TSRI chemists develop new cell-marking method

Link between Parkinson's and benomyl

ParoChip can allow dentists to quickly detect and analyze periodontitis pathogens

Whole Genome Mapping and NGS deliver high-quality reference genome of domestic goat

UV nail lamp use not associated with skin cancer risk

Lapatinib benefits found for HER2-positive early-stage patients

NeoGenomics launches FISH assay for surveillance of patients with Barrett's Esophagus

Immunohistochemistry reliable in identifying ALK rearrangement: Study

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

New diagnostic assay for screening ALK fusions in non-small cell lung carcinoma

Using Nanoparticles to Target Cancer

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

Paper reveals how 'kinase' is distributed across membranes

New study on mice could open door to methods of regulating cell proliferation in humans

Scientists identify two genes involved in establishing neuronal circuits required for breathing

Two Sanford-Burnham projects win International Space Station Research Competition

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