Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

AI system can help detect the degree and severity of heart transplant rejection

Heart transplantation can be a lifesaving operation for patients with end-stage heart failure. However, many patients experience organ transplant rejection, in which the immune system begins attacking the transplanted organ.

21 Mar 2022

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

In an unparalleled effort to deliver outstanding comprehensive care and to employ revolutionary approaches to novel therapeutics around the skin condition alopecia areata, the Mount Sinai Health System has launched the Alopecia Areata Center of Excellence.

21 Mar 2022

Sectra signs digital pathology contract with Erasmus MC

International medical imaging IT and cybersecurity company Sectra has signed a digital pathology contract with Erasmus University Medical Center (Erasmus MC) in the Netherlands.

21 Mar 2022

Low levels of SARS-CoV-2 viremia associated with ‘COVID placentitis’ and stillbirths

Researchers hypothesize that patients with COVID placentitis were more likely to contract viremia.

20 Mar 2022

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Researchers assessed the role of hypoxia-inducible factors in SARS-CoV-2 infection, respiratory symptoms, and epithelial damage.

18 Mar 2022

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Researchers tested the effectiveness of the BCG vaccine in SARS-CoV-2-infected Syrian hamsters.

18 Mar 2022

Excessive daytime napping among older people may foreshadow dementia

Daytime napping among older people is a normal part of aging – but it may also foreshadow Alzheimer's disease and other dementias.

18 Mar 2022

Researchers identify a gene that could prevent Parkinson’s disease

Parkinson's disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons.

17 Mar 2022

Blood test may identify risk of stillbirth and placentitis in pregnant patients with COVID-19

A small preliminary study from Northwestern Medicine has shown that a blood test may identify risk of stillbirth and placentitis in pregnant individuals who have had COVID-19.

16 Mar 2022

Study finds a promising new target for immunity-boosting cancer treatments

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a study from researchers at Weill Cornell Medicine and Albert Einstein College of Medicine.

16 Mar 2022

Neuropsychiatric symptoms develop predominantly due to Alzheimer’s pathology, not cognitive decline

Alzheimer's disease (AD) eventually leads to severe cognitive decline, but most affected individuals also develop distressing neuropsychiatric symptoms.

16 Mar 2022

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and the skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau.

15 Mar 2022

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

People who gained immunity - either through vaccination or exposure - against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant.

11 Mar 2022

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Two multi-institutional teams led by Weill Cornell Medicine scientists have been awarded grant support from the Starr Cancer Consortium. Both grants will fund work applying new technologies to develop more detailed knowledge of tumor biology, with one team focusing on Hodgkin lymphoma and the other on the purity of tumor samples on pathology slides.

10 Mar 2022

Blood test shows promise to identify Alzheimer's changes in the brain before symptom onset

The University of Kentucky's Sanders-Brown Center on Aging has been around for nearly half a century. In that time, they have built an international reputation for best-in-class research into a disease that kills more people every year than breast and prostate cancer combined – Alzheimer's disease.

10 Mar 2022

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Amyloid beta, a protein known to build up in the brains of people with Alzheimer's disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

10 Mar 2022

Study examines the safety, efficacy of old 'forgotten' antibiotic for treating resistant bacterial infections

The results make it possible to expand the treatment options for infections for which few alternatives exist, while at the same time helping to avoid increasing resistance to the usual drugs.

10 Mar 2022

Study provides insights into how early life events can affect brain wiring patterns

A new study of brain development in mice shortly after birth may provide insights into how early life events can affect wiring patterns in the brain that manifest as disease later in life – specifically such disorders as schizophrenia, epilepsy and autism.

10 Mar 2022

NCCN publishes new resources for treating rare tumor types

The National Comprehensive Cancer Network - an alliance of leading cancer centers - today announced the publication of new NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Ampullary Adenocarcinoma.

9 Mar 2022

Pathology News and Research

Further Reading

New computational approach creates spatial maps of single-cell data within tissues

AI system can help detect the degree and severity of heart transplant rejection

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

Sectra signs digital pathology contract with Erasmus MC

Low levels of SARS-CoV-2 viremia associated with ‘COVID placentitis’ and stillbirths

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Excessive daytime napping among older people may foreshadow dementia

Researchers identify a gene that could prevent Parkinson’s disease

Blood test may identify risk of stillbirth and placentitis in pregnant patients with COVID-19

Study finds a promising new target for immunity-boosting cancer treatments

Neuropsychiatric symptoms develop predominantly due to Alzheimer’s pathology, not cognitive decline

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Blood test shows promise to identify Alzheimer's changes in the brain before symptom onset

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Study examines the safety, efficacy of old 'forgotten' antibiotic for treating resistant bacterial infections

Study provides insights into how early life events can affect brain wiring patterns

NCCN publishes new resources for treating rare tumor types

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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