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Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal cord.

24 Sep 2024

Study reveals how inflammatory immune cells enhance prostate cancer resistance

There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully understood.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

Brazil nut consumption in an energy-restricted diet significantly reduced inflammation and improved intestinal permeability in overweight/obese women, likely due to selenium’s anti-inflammatory properties.

23 Sep 2024

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions of patients worldwide.

23 Sep 2024

New CRISPR model offers deeper insight into prostate cancer metastasis

A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given Weill Cornell Medicine researchers and their colleagues a deeper insight into how prostate cancer spreads or metastasizes.

23 Sep 2024

3DHISTECH launches the new flagship P480 2nd Generation, powered with polarization

3DHISTECH unveils its latest flagship product, the P480 2nd Gen. Leveraging a decade of research and diagnostic excellence established by the P480, the P480 2nd Gen introduces new features and incorporates notable enhancements to meet the evolving needs and exigencies of modern digitized laboratories.

From 3DHISTECH 23 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Study reveals anti-tumor properties of food antigens

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative medical sciences (IMS) in Japan have discovered that food antigens like milk proteins help keep tumors from growing in our guts, specifically the small intestines.

23 Sep 2024

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

Cranberry juice: A natural boost for women's skin health

A polyphenol-rich cranberry beverage was found to improve skin elasticity, reduce UV-induced erythema, and modulate the skin microbiome, with effects most pronounced in women aged 40 and older.

22 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024

Study reveals sex differences in T-cell responses among lung cancer patients

Researchers at Saint Louis University School of Medicine investigated differences in T-cell responses between male and female patients with lung cancer that may help direct future treatments.

20 Sep 2024

UCLA develops largest collection of patient-derived organoids for sarcoma research

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.

20 Sep 2024

Promising antidepressant offers hope for glioblastoma treatment

Glioblastoma is a particularly aggressive brain tumor that at present is incurable. Cancer doctors can extend patients' life expectancy through operations, radiation, chemotherapy or surgical interventions. Nevertheless, half of patients die within twelve months of diagnosis.

20 Sep 2024

Anti-fibrotic drug shows promise in breast cancer

The most common breast cancer is HER2-negative, so called because it has low amounts of one of the proteins that contribute to tumor cell growth, HER2. Despite this common trait, the development of HER2-negative cancers varies among patients, so one goal is to be able to classify tumors in more detail and thus determine the best treatment for each case.

20 Sep 2024

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

New workflow enhances proton therapy by adapting to daily changes in cancer patients

In the treatment of cancer patients, irradiation can be adapted anew each day to the position of the tumor and conditions in the body.

19 Sep 2024

Study reveals MYC gene's role in prostate cancer initiation and progression

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene - a well-known cancer-causing gene - sets off a cascade of events that leads to both initiation and progression of the disease.

19 Sep 2024

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Tumor News and Research

Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Study reveals how inflammatory immune cells enhance prostate cancer resistance

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

New CRISPR model offers deeper insight into prostate cancer metastasis

3DHISTECH launches the new flagship P480 2nd Generation, powered with polarization

Yoyo dieting alters gut health, driving weight regain and inflammation

Study reveals anti-tumor properties of food antigens

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Cranberry juice: A natural boost for women's skin health

Fever enhances immune cell activity and induces mitochondrial stress

Study reveals sex differences in T-cell responses among lung cancer patients

UCLA develops largest collection of patient-derived organoids for sarcoma research

Promising antidepressant offers hope for glioblastoma treatment

Anti-fibrotic drug shows promise in breast cancer

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

New workflow enhances proton therapy by adapting to daily changes in cancer patients

Study reveals MYC gene's role in prostate cancer initiation and progression

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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