Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers decipher genetic mechanisms governing the speed of protein synthesis

In all eukaryotic organisms, genetic material is stored in the cell nucleus in the form of DNA. In order to be used, this DNA is first transcribed into messenger RNA in the cell cytoplasm, then translated into protein with the help of ribosomes, small machines capable of decoding messenger RNA to synthesise the appropriate proteins.

31 Aug 2021

Research analyzes the role of RNA tags in Alzheimer’s disease

Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.

28 Aug 2021

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

NYU Tandon professors Mary Cowman and Jin Ryoun Kim recently published a paper describing a novel peptide with broad therapeutic potential to combat chronic inflammation in multiple diseases.

28 Aug 2021

Fine particle pollution doubles the risk of Alzheimer's disease in Black women

Fine particle pollution may be one reason why Black women have double the risk of developing Alzheimer's than white women, suggests new research from the Keck School of Medicine of USC.

27 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Testing for inflammatory proteins will help diagnose earlier onset, progression of Alzheimer’s disease

Testing for some inflammatory proteins associated with the nervous and immune systems will help diagnose the earlier onset and progression of Alzheimer's disease, according to a Rutgers study.

26 Aug 2021

Higher intake of specific nutrients linked to lower brain iron and better cognition in older adults

Research conducted at the University of Kentucky College of Medicine suggests that higher intake of specific nutrients is associated with lower brain iron concentration and better cognitive performance in older adults.

26 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

For the first time, Penn Medicine researchers showed how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers.

26 Aug 2021

Research shows increase in the registration of dementia as underlying cause of death

It is well known that dementia is associated with increased mortality. New scientific research shows how in recent years more deaths are being registered with dementia as the underlying cause of death.

26 Aug 2021

Review highlights similarities between long COVID and chronic fatigue syndrome

A team of researchers, including two from Johns Hopkins Medicine, have published a review article highlighting similarities between certain lingering symptoms following COVID-19 illness — a condition called "long COVID" — and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating, complex disorder previously known as chronic fatigue syndrome.

26 Aug 2021

Athletes with history of concussions may show subtle and chronic brain changes

A new study suggests athletes with a history of concussion may show more brain injury from a later concussion, particularly in middle regions of the brain that are more susceptible to damage, when compared to athletes with no history of concussion.

26 Aug 2021

Brain refreshing takes place during the dream-active phase of sleep

Scientists have long wondered why almost all animals sleep, despite the disadvantages to survival of being unconscious.

25 Aug 2021

Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Wake Forest School of Medicine and the American Federation for Aging Research have received a renewal award for up to $5 million over five years from the National Institute on Aging, National Institutes of Health, to continue their management of the Research Centers Collaborative Network.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Alzheimer's Disease News and Research

Further Reading

Researchers decipher genetic mechanisms governing the speed of protein synthesis

Research analyzes the role of RNA tags in Alzheimer’s disease

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

Fine particle pollution doubles the risk of Alzheimer's disease in Black women

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Testing for inflammatory proteins will help diagnose earlier onset, progression of Alzheimer’s disease

Higher intake of specific nutrients linked to lower brain iron and better cognition in older adults

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

Research shows increase in the registration of dementia as underlying cause of death

Review highlights similarities between long COVID and chronic fatigue syndrome

Athletes with history of concussions may show subtle and chronic brain changes

Brain refreshing takes place during the dream-active phase of sleep

Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Regular physical exercise modulates iron metabolism in Alzheimer’s mouse model

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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