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CRISPR Cas12a3: A precise tool to halt viral protein production

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

7 Jan 2026

Genetic study reveals how DNA repeats expand with age

An analysis of genetic data from over 900,000 people shows that certain stretches of DNA, made up of short sequences repeated over and over, become longer and more unstable as we age.

7 Jan 2026

Replenishing mitochondria significantly reduces chronic nerve pain, research shows

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

7 Jan 2026

Newly discovered molecule could be a game-changer in the fight against deadly fungi

Fungal infections kill millions of people each year, and modern medicine is struggling to keep up. But researchers at McMaster University have identified a molecule that may help turn the tide — butyrolactol A, a chemical compound that targets a deadly, disease-causing fungi called Cryptococcus neoformans.

7 Jan 2026

New insight into how our bodies keep brain parasite Toxoplasma gondii in check

The parasite that may already live in your brain can infect the very immune cells trying to destroy it, but new UVA Health research reveals how our bodies keep it under control.

7 Jan 2026

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastoma

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor.

7 Jan 2026

Gut-microbe-derived molecules may play a key role in shaping the developing immune system

An international research team has uncovered compelling evidence that gut-microbe-derived molecules may play an important role in shaping the developing immune system during early childhood.

7 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

Newly discovered molecules accelerate the removal of immune-modulating enzyme

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

7 Jan 2026

Study shows beneficial impact of natural light on people with type 2 diabetes

Metabolic diseases have reached epidemic proportions in our society, driven by a sedentary lifestyle coupled with circadian misalignment - a desynchrony between our intrinsic biological clocks and environmental signals.

7 Jan 2026

Nuclera eProtein Discovery System installed at leading universities in Taiwan

Nuclera, the biotechnology company accelerating drug discovery by providing rapid, easy access to functional proteins through its benchtop eProtein Discovery™ System, today announced that it has completed the first installations of eProtein Discovery in Asia, with systems now operational at the Department of Pharmacy and the Department of Chemistry at the National Taiwan University (NTU) College of Medicine and the Center for Bioscience and Biotechnology and Department of Chemical Engineering at the National Cheng Kung University (NCKU).

7 Jan 2026

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving treatment adherence in the PIONEER trial.

7 Jan 2026

Parkinson’s disease may stem from iron starvation rather than iron overload

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that iron sequestration, not iron toxicity alone, may impair dopamine synthesis and neuronal survival.

6 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Charting brain cell epigenomics to reveal origins of psychiatric disorders

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Maria Margarita Behrens recounts an extraordinary scientific journey that wound through four countries and multiple disciplines before arriving at fundamental questions about how the brain develops and what goes wrong in psychiatric disorders.

6 Jan 2026

New breakthrough could modernize treatment for glioblastoma

Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma, a fast-growing and deadly form of brain cancer.

6 Jan 2026

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest.

6 Jan 2026

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

Accelerating advancements in cancer prevention and cures, Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, has received a $900,000 grant from the Cancer Prevention and Research Institute of Texas to develop stronger and more targeted anti-tumor therapy for pancreatic and lung cancer.

6 Jan 2026

Cell News and Research

CRISPR Cas12a3: A precise tool to halt viral protein production

Genetic study reveals how DNA repeats expand with age

Replenishing mitochondria significantly reduces chronic nerve pain, research shows

Newly discovered molecule could be a game-changer in the fight against deadly fungi

New insight into how our bodies keep brain parasite Toxoplasma gondii in check

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastoma

Gut-microbe-derived molecules may play a key role in shaping the developing immune system

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Newly discovered molecules accelerate the removal of immune-modulating enzyme

Study shows beneficial impact of natural light on people with type 2 diabetes

Nuclera eProtein Discovery System installed at leading universities in Taiwan

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Parkinson’s disease may stem from iron starvation rather than iron overload

The gut is not just digestive and new evidence shows it actively controls brain function

A single immune protein may help explain why kidney and heart disease often develop together

Charting brain cell epigenomics to reveal origins of psychiatric disorders

New breakthrough could modernize treatment for glioblastoma

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

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