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Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Research over decades has implicated aberrant autophagy and lysosomal function as reliable markers and therapeutic targets for neurodegenerative diseases.

27 Mar 2014

Research points strong reason to develop new class of antidepressant drug

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

From The University of Manchester 27 Mar 2014

Researchers decode effects of antimicrobial peptide on bacterial cells

The team of Julia Bandow, who heads the RUB's Junior Research Group Microbial Antibiotic Research, has been studying the MP196 peptide as a representative of a group of very small positively charged peptides that consist of some four to ten amino acids.

27 Mar 2014

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

Nasal spray holds promise as potential alternative therapeutic approach for depression

A nasal spray that delivers a peptide to treat depression holds promise as a potential alternative therapeutic approach, research from the Centre for Addiction and Mental Health (CAMH) shows.

25 Mar 2014

CSP analogues may attenuate S. pneumoniae virulence, resistance

The spread of virulent, antibiotic-resistant strains of Streptococcus pneumoniae may be controllable through the use of competence-stimulating peptide analogues, US researchers believe.

24 Mar 2014

Scientists produce antibiotic whose biological activity can be controlled with light

Scientists of the KIT and the University of Kiev have produced an antibiotic, whose biological activity can be controlled with light. Thanks to the robust diarylethene photoswitch, the antimicrobial effect of the peptide mimetic can be applied in a spatially and temporally specific manner.

21 Mar 2014

New improved mass spectrometry for analysis of chemical and biological materials

When it comes to analyzing cell components or body fluids or developing new medications, there is no way around mass spectrometry. Mass spectrometry is a highly sensitive method of measurement that has been used for many years for the analysis of chemical and biological materials.

19 Mar 2014

Chemical engineers design way to manufacture peptides in mere hours

Small protein fragments, also called peptides, are promising as drugs because they can be designed for very specific functions inside living cells. Insulin and the HIV drug Fuzeon are some of the earliest successful examples, and peptide drugs are expected to become a $25 billion market by 2018.

19 Mar 2014

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

University of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease.

18 Mar 2014

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls.

18 Mar 2014

Findings support development of cysteine protease inhibitors as new drug target for AD

A team of scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and San Diego-based American Life Science Pharmaceuticals, Inc., report that cathepsin B gene knockout or its reduction by an enzyme inhibitor blocks creation of key neurotoxic pGlu-Aβ peptides linked to Alzheimer's disease (AD). Moreover, the candidate inhibitor drug has been shown to be safe in humans.

18 Mar 2014

Peptides News and Research

Discovery could lead to new medications for cancer, say Rice University scientists

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Research points strong reason to develop new class of antidepressant drug

Researchers decode effects of antimicrobial peptide on bacterial cells

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Nasal spray holds promise as potential alternative therapeutic approach for depression

CSP analogues may attenuate S. pneumoniae virulence, resistance

Scientists produce antibiotic whose biological activity can be controlled with light

New improved mass spectrometry for analysis of chemical and biological materials

Chemical engineers design way to manufacture peptides in mere hours

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

Findings support development of cysteine protease inhibitors as new drug target for AD

Rice University technique able to analyze conformations of complex molecular machines

ATS develops clinical practice guidelines to help clinicians identify, manage patients with sickle cell disease

New sweetener from tequila plant may aid diabetes, weight loss

Researchers map visual system amplifier that is directly activated by walking or running

Japanese PAH patient prognosis ‘good’

Discovery Laboratories reports net loss of $11.7 million for fourth quarter 2013

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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