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Semaglutide cuts death rates from cardiovascular disease and COVID-19

Patients taking semaglutide injections are less likely to die of any cause, including from cardiovascular disease and infections like COVID-19, an international study led by researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, finds.

30 Aug 2024

Disability rights activist pushes government to let him participate in society

Garret Frey refuses to be sidelined. Frey has been paralyzed from the neck down for more than 37 of his 42 years. He has spent decades rejecting the government's excuses when he and others with disabilities are denied the support they need to live in their own homes and to participate in society.

23 Aug 2024

AI tools accelerate understanding of cardiac arrhythmia risks in lung cancer treatment

Researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

20 Aug 2024

Leading health issues affecting older adults before the 2024 elections

Researchers surveyed adults aged ≥50 years to identify the most salient health concerns before the 2024 elections in the United States.

20 Aug 2024

Brain scans can detect consciousness in some unresponsive patients

New research co-led by experts at Mass General Brigham found that brain scans can detect consciousness in some patients with brain injury who are unresponsive.

14 Aug 2024

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Aspirin may lower colorectal cancer risk for people with unhealthy lifestyles

Regular aspirin may help lower risk of colorectal cancer in people with greater lifestyle-related risk factors for the disease, according to a study led by researchers at Mass General Brigham.

1 Aug 2024

Higher Brain Care Score associated with lower risk of late-life depression

Late-life depression, typically defined as depression with onset in individuals over 60 years of age, can affect up to a third or more of people older than 60 and can be debilitating.

23 Jul 2024

States set minimum staffing levels for nursing homes. Residents suffer when rules are ignored or waived.

For hours, John Pernorio repeatedly mashed the call button at his bedside in the Heritage Hills nursing home in Rhode Island.

12 Jul 2024

Advocate Health selected for CMS GUIDE Model aimed at advancing dementia care

Advocate Health has been selected by the Centers for Medicare and Medicaid Services (CMS) to participate in the Guiding an Improved Dementia Experience (GUIDE) Model, aimed to support advanced dementia patients and their caregivers in bridging the gaps associated with inequalities in dementia care.

10 Jul 2024

Study highlights hidden aggressiveness in Gleason Grade Group 1 prostate cancer

New research highlights the challenge of balancing the risks of overdiagnosing and underdiagnosing prostate cancer early enough to intervene and minimize risk of death.

9 Jul 2024

Majority of people prefer hospital-level care at home

Hospital-level care provided in a patient's own home is appealing to a majority of people for its convenience, comfort and effectiveness, according to a USC Schaeffer Center study.

8 Jul 2024

Study reveals link between the use of antipsychotics in dementia and socioeconomic status

A study led by the Economic Evaluation of Chronic Diseases group of Biogipuzkoa Health Research Institute has revealed the relationship between the use of antipsychotics in dementia and socioeconomic status.

2 Jul 2024

Quality Improvement Program for Missouri saves millions and enhances elder care

A researcher at the University of Missouri has developed a program that improves the quality of care and reduces avoidable hospitalizations in nursing homes - saving Missouri nursing homes and Medicare millions of dollars and allowing Missouri nursing homes to invest more in retaining their most skilled staff members.

24 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

New AI tool could revolutionize clinical trial efficiency and cost

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

17 Jun 2024