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New findings explain how lysosomal defects trigger neuronal energy failure

Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell type-specific atlas of lysosomes in the brain, the cell organelles which are responsible for degradation and recycling processes.

23 Jan 2026

Decoupling of metabolism and vasculature in tumors revealed by novel Capillary-Cell microscopy

A multidisciplinary team from Harvard Medical School, Duke University, and Massachusetts General Hospital has developed the dual-scale Capillary-Cell (CapCell) microscope, a revolutionary tool for visualizing tumor metabolism and vasculature dynamics.

21 Jan 2026

Study shows membrane chemistry influences early cell-like compartment evolution

Modern cells are complex chemical entities with cytoskeletons, finely regulated internal and external molecules, and genetic material that determines nearly every aspect of their functioning. This

21 Jan 2026

Far-red light suppresses biofilm formation and virulence in pathogenic bacteria

Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for organisms ranging from single-celled bacteria to human beings.

20 Jan 2026

COVID-19 severity is linked to changes in mitochondrial DNA methylation

This study examined mitochondrial and nuclear-encoded mitochondrial DNA methylation in Indian patients with severe COVID-19 and found region-specific differential methylation linked to disease severity. Pathway analyses and protein assays implicated disrupted mitochondrial metabolism and dynamics, suggesting a role for mitochondrial epigenetic regulation in COVID-19 pathophysiology.

20 Jan 2026

Customizable protein platforms offer new hope for cancer treatment

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the University of Massachusetts Amherst, could have applications beyond cancer to a wide range of immunological diseases, members of the interdisciplinary research team say.

20 Jan 2026

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have opened a clinical trial that will look at whether combining precision radiation with a targeted radioactive therapy drug can help patients with recurrent prostate cancer delay progression, while delaying or avoiding the side effects of long-term hormone therapy.

16 Jan 2026

Monolithic photocurable hyaluronic acid patch achieves strong wet adhesion for durotomy repair

Durotomy is a common neurosurgical complication involving a tear in the dura mater, the protective membrane surrounding the brain and spinal cord.

16 Jan 2026

CTDNEP1 identified as potential tumor suppressor in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the pancreatic duct.

15 Jan 2026

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Vegetarian women show subtle changes in cellular health markers

Slovak university women on vegetarian diets exhibit small bioelectrical impedance variations, suggesting potential insights into body composition and health.

13 Jan 2026

Discovery lays foundation for understanding how the cell senses membrane injuries

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell.

12 Jan 2026

One Health action needed as environmental reservoirs fuel drug-resistant infections

Environmental antimicrobial resistance is turning rivers, soils, and even the air into hidden highways for "superbugs," according to a new review that calls for urgent, coordinated action across human, animal, and environmental health.

9 Jan 2026

Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life

The origin of life on Earth becomes even more fascinating and complex as we peer into the mysterious world of viruses.

8 Jan 2026

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

The study reveals that environmental stressors do not merely kill bacteria; they can also prime surviving cells to take up resistance genes more efficiently, raising concerns about how antibiotic-resistant bacteria may spread in aquatic environments.

8 Jan 2026

Aston University and PFE Medical partner to create biodegradable gloves from food waste

Aston University and Midlands-based company PFE Medical are teaming up to create biodegradable gloves made from food waste for use in the NHS.

7 Jan 2026

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.

7 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Membrane News and Research

New findings explain how lysosomal defects trigger neuronal energy failure

Decoupling of metabolism and vasculature in tumors revealed by novel Capillary-Cell microscopy

Study shows membrane chemistry influences early cell-like compartment evolution

Far-red light suppresses biofilm formation and virulence in pathogenic bacteria

COVID-19 severity is linked to changes in mitochondrial DNA methylation

Customizable protein platforms offer new hope for cancer treatment

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

Monolithic photocurable hyaluronic acid patch achieves strong wet adhesion for durotomy repair

CTDNEP1 identified as potential tumor suppressor in pancreatic ductal adenocarcinoma

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Vegetarian women show subtle changes in cellular health markers

Discovery lays foundation for understanding how the cell senses membrane injuries

One Health action needed as environmental reservoirs fuel drug-resistant infections

Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

Aston University and PFE Medical partner to create biodegradable gloves from food waste

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

A single immune protein may help explain why kidney and heart disease often develop together

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