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Researchers identify a potential new drug for NASH-related fibrosis

Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with nonalcoholic steatohepatitis (NASH)-related fibrosis.

26 Jun 2023

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown.

23 Jun 2023

Study finds the risk of recurrence of active disease in older patients with MS after discontinuing therapy

An article published today in the journal Lancet Neurology evaluates the risk of recurrence of active disease in older patients with multiple sclerosis after discontinuing disease-modifying therapies.

23 Jun 2023

Treatment with dupilumab leads to sustained improvements in COPD patients with type 2 inflammation

Chronic obstructive pulmonary disease patients with type 2 inflammation saw rapid and sustained improvements in their disease after treatment with the monoclonal antibody dupilumab, according to a yearlong, Phase 3 clinical trial reported in the New England Journal of Medicine.

20 Jun 2023

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

16 Jun 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin-;generally prepared from porcine intestinal mucosa in China-;was threatened by African swine fever in 2018.

15 Jun 2023

Study offers a new perspective on the reproductive toxicity of phthalates

Prenatal exposure to chemicals called phthalates, which are used in hundreds of products, may lead to hormonal changes in females that could affect their future fertility, suggests a study in mice being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

'Concerning' CT findings may be an important barrier to discharge of low-risk pulmonary embolism patients

Of approximately 250,000 Americans diagnosed with acute pulmonary embolism, or PE, in emergency departments each year, most are hospitalized.

15 Jun 2023

New light-responsive membrane transporters for the translocation of peptide cargos inside cells

Crossing the membrane is a major challenge on the journey through the cell. Large biomolecules usually benefit from different transport strategies to overcome the lipid bilayer, so the design and synthesis of new carriers is key for the delivery of hydrophilic substances, such as pharmaceuticals, into the cell.

14 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

13 Jun 2023

Bamboo's hidden treasures: unveiling the possible health-boosting powers of leaf and sheath extracts

Researchers explored the antioxidant and anti-inflammatory properties of bamboo leaves and sheaths.

13 Jun 2023

Debt deal leaves health programs (mostly) intact

A final deal cut between President Joe Biden and House Republicans extends the U.S. debt ceiling deadline to 2025 and reins in some spending.

8 Jun 2023

Experimental drug may slow the progression of atherosclerosis

An experimental drug already tested as a potential treatment for cancer, lung disease, and Alzheimer's disease may slow the progression of atherosclerosis that leads to heart disease, a new study shows.

8 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

Study suggests possible new treatment option for people with slow-growing but deadly brain tumor

In an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening.

4 Jun 2023

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity of key cells and signaling pathways, a new study shows.

2 Jun 2023

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Lupus Therapeutics announced the start of a collaboration to conduct three Phase 3 clinical trials testing an investigational therapeutic ianalumab for systemic lupus erythematosus and lupus nephritis.

2 Jun 2023

Many people living in the ‘diabetes belt’ are plagued with medical debt

Delores Lowery remembers vividly the day in 2016 when she was working in a weaving plant near her home in Bennettsville, South Carolina, and the world around her seemed to go dim.

30 May 2023

High prevalence of galactagogue use among breastfeeding mothers in U.S.

Researchers describe the prevalence of galactagogue use among breastfeeding mothers in the United States and their perceived effects on milk production.

29 May 2023

Physical activity in the afternoon provides greatest improvements in glucose control for patients with type 2 diabetes

Over 37 million Americans have diabetes, and 90-95% of that population are diagnosed with type 2 diabetes.

25 May 2023

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Pharmaceuticals News and Research

Researchers identify a potential new drug for NASH-related fibrosis

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

Study finds the risk of recurrence of active disease in older patients with MS after discontinuing therapy

Treatment with dupilumab leads to sustained improvements in COPD patients with type 2 inflammation

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Study offers a new perspective on the reproductive toxicity of phthalates

'Concerning' CT findings may be an important barrier to discharge of low-risk pulmonary embolism patients

New light-responsive membrane transporters for the translocation of peptide cargos inside cells

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Bamboo's hidden treasures: unveiling the possible health-boosting powers of leaf and sheath extracts

Debt deal leaves health programs (mostly) intact

Experimental drug may slow the progression of atherosclerosis

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

Study suggests possible new treatment option for people with slow-growing but deadly brain tumor

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Many people living in the ‘diabetes belt’ are plagued with medical debt

High prevalence of galactagogue use among breastfeeding mothers in U.S.

Physical activity in the afternoon provides greatest improvements in glucose control for patients with type 2 diabetes

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