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New approach to kidney transplant listing could improve outcomes and equity

The current kidney transplant waitlisting criterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73m2) and does not consider an individual's risk of progressing to kidney failure.

13 Nov 2025

Age and flu vaccine type influence immune activation

New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the vaccine type and age of the patient.

12 Nov 2025

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Texas' transitional dialysis program led to significant decline in utilization of emergency dialysis

The cost of emergency dialysis is estimated to be 8-times that of in-center dialysis. A new study reveals that a transitional dialysis program piloted in Travis County (Austin, TX) resulted in a significant decrease in emergency department visits and hospital admissions for emergency dialysis by providing a pathway for outpatient dialysis in uninsured patients.

10 Nov 2025

Expanding the waitlisting criteria for kidney transplantation could improve patient outcomes

The current kidney transplant waitlistingcriterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73m2) and does not consider an individual’s risk of progressing to kidney failure.

10 Nov 2025

Study shows record surge in reduced kidney function worldwide

Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew and aged, making it for the first time a top 10 cause of death worldwide.

8 Nov 2025

Pediatric patients with primary glomerular diseases may experience faster kidney function decline

New research reveals that contrary toconventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets of children and young adults may experience faster kidney function decline than older patients.

7 Nov 2025

Mismatch in kidney tests may reveal hidden health risks

A mismatch between two common tests for kidney function may indicate a higher risk for kidney failure, heart disease, and death, a new study shows.

7 Nov 2025

Study identifies molecular brake that controls overactive killer T cells

"Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?"

6 Nov 2025

Mayo Clinic scientists create stem cell patch to heal hearts without surgery

Mayo Clinic researchers have developed a pioneering method to mend damaged hearts without open-heart surgery, an advance that could one day transform the treatment of heart failure.

5 Nov 2025

Machine-preserved kidneys show better function ten years after transplant

A long-term follow-up study from a consortium of six European countries, coordinated by the department of Surgery of the University Medical Center Groningen (UMCG) shows that, even 10 years after transplantation, deceased-donor kidneys performed better when they were preserved on a machine between organ retrieval and transplantation than those that underwent static cold storage before implantation.

5 Nov 2025

NYU Langone Health begins first clinical trial of gene-edited pig kidney transplants

The first surgery in a clinical trial testing the safety and efficacy of gene-edited pig kidney transplants in patients with end-stage renal disease was recently performed at NYU Langone Health.

5 Nov 2025

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

Advances in diagnosis and management of systemic light chain amyloidosis

Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to progressive structural and functional impairment.

30 Oct 2025

Rapamycin shows promise in treating cold tumors with specific gene mutation

Immune checkpoint inhibitors (ICIs) emerged in the US about 15 years ago as an exciting class of cancer treatments that have achieved complete and durable remissions for thousands of people with end-stage metastatic cancers.

29 Oct 2025

Specialized type of cardiac fibroblasts can actively worsen heart failure

Heart failure (HF) is one of the leading causes of death and disability worldwide, affecting millions of people and placing an enormous burden on healthcare systems.

29 Oct 2025

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 Oct 2025

Opt-out organ donation policies may reduce living organ donations

Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as a way to increase the supply of desperately needed organs.

28 Oct 2025