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Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

Waters launches new RUO LC-MS test method to advance infectious disease research

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

4 Jun 2021

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

4 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

Optimized Tube Plate for Enzyme Studies

BioChromato Inc. has developed an enzyme assay product - the RAPID Tube Plate 600 (TP-600) that is helping deliver outstanding results in in vitro metabolic stability studies.

From BioChromato Inc. 3 Jun 2021

Study compares Pfizer and Moderna mRNA vaccine-elicited response to SARS-CoV-2 variants

A new study has been published on the bioRxiv preprint server which focuses on the correlation between the vaccine-triggered Immunoglobulin G (IgG) levels and neutralization titers against SARS-CoV-2 variants. Further, neutralization activities against the variants (B.1.1.7, B.1.525, and B.1.351), using Pfizer or Moderna vaccine, sera were assessed.

3 Jun 2021

Researchers detect Zika virus RNA in free-ranging African bats

A team of Colorado State University scientists, led by veterinary postdoctoral fellow Dr. Anna Fagre, has detected Zika virus RNA in free-ranging African bats. RNA, or ribonucleic acid, is a molecule that plays a central role in the function of genes.

3 Jun 2021

Depleting SIRPα-deficient in macrophages activate tumor antigen-specific cytotoxic T cells

In a study that will be published in Nature Communications on May 28, 2021, a research team led by Dr. Yuan Liu from Georgia State University reports that intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells to eliminate various syngeneic cancers under radiotherapy.

2 Jun 2021

Novel antibody engineering approach

Scientists from the Johns Hopkins University School of Medicine, USA, have recently developed an Antibody Display technology by grafting the second extracellular domain of tetraspanin12 (Tspan12EC2) and the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein on the heavy chain complementarity-determining region 3 (CDR3).

2 Jun 2021

Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment

They have identified a group of kite-shaped compounds that are highly specific to SARS-CoV-1 and SARS-CoV-2. These compounds demonstrate high potency in inhibiting SARS-CoV-2 infection at early entry steps. The study is currently available on the bioRxiv* preprint server.

2 Jun 2021

Compelling evidence of SARS-CoV-2 exposure and neutralizing antibodies in domestic cats in Peru

Although Peru is one of the countries most affected by the pandemic, no studies had been conducted to investigate SARS-CoV-2 seroprevalence among domestic cats. Recently, researchers from Peru demonstrated the presence of neutralizing antibodies for the receptor binding-domain (RBD) of the SARS-CoV-2 spike protein in cats in Lima, Peru. The owners of the cats in the study had confirmed SARS-CoV-2 infection.

1 Jun 2021

A novel multiplexed diagnostic approach for COVID-19

Researchers developed a platform for detecting the virus directly from a patient's sample as well as the immune response through antibodies such as IgG and IgM.

31 May 2021

Corilagin: could a plant compound used in Chinese herbal medicine help prevent COVID-19?

The study, published in the journal Phytomedicine, characterized an active compound, corilagin (a derivative from Phyllanthus urinaria), as potential SARS-CoV-2 entry inhibitors for its preventive application in daily antiviral hygiene products.

31 May 2021

Aptamer Group collaborates with world-leading pharmaceutical company to evaluate Optimer technology

Aptamer Group today announced that it has signed an agreement with the multinational pharmaceutical and biopharmaceutical company Takeda.

From Aptamer Group 28 May 2021

Corning launches HepGo Assay-ready 3D liver spheroid kit

Corning Incorporated today announced the launch of its HepGo™ Assay-ready 3D liver spheroid kit, the first plug-and-play solution to include 96 pre-plated primary human hepatocyte (PHH) spheroids in a single-spheroid microplate (one uniform spheroid per well) and HepGo Hepatocyte companion cell culture media.

28 May 2021

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

A new paper by an international team of researchers describes experimental evidence of the antiviral efficacy of a marine compound called plitidepsin against SARS-CoV-2. The findings show that plitidepsin inhibits SARS-CoV at low concentrations, as observed by a thousand-fold reduction in genomic RNA and viral titers in cells exposed to the virus in culture when treated.

27 May 2021

Rapid Novor First to Decode Polyclonal Antibodies Using Only Proteomics

Novel antibody discovery platform REpAb® unlocks direct access to key antibodies through next-generation protein sequencing

From Rapid Novor Inc 27 May 2021

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

From Waters Corporation 27 May 2021

Study shows CoronaVac to have high seroconversion rate after 40 days

Researchers from the Federal University of Paraná, Brazil, looked into the seroconversion rate after vaccination with the CoronaVac. Using immunoassays, they measured the immunoglobulins (IgG) for anti-nucleocapsid protein (anti-N) antibodies and anti-spike-1 (anti-S1) protein antibodies.

27 May 2021

Astodrimer sodium exhibits potent virucidal and antiviral activity against SARS-CoV-2 in vitro

Researchers from the US and Australia recently conducted some studies to assess the in vitro antiviral and virucidal (irreversible) activity of astodrimer sodium against SARS-CoV-2.

26 May 2021

Assay News and Research

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Waters launches new RUO LC-MS test method to advance infectious disease research

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

Optimized Tube Plate for Enzyme Studies

Study compares Pfizer and Moderna mRNA vaccine-elicited response to SARS-CoV-2 variants

Researchers detect Zika virus RNA in free-ranging African bats

Depleting SIRPα-deficient in macrophages activate tumor antigen-specific cytotoxic T cells

Novel antibody engineering approach

Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment

Compelling evidence of SARS-CoV-2 exposure and neutralizing antibodies in domestic cats in Peru

A novel multiplexed diagnostic approach for COVID-19

Corilagin: could a plant compound used in Chinese herbal medicine help prevent COVID-19?

Aptamer Group collaborates with world-leading pharmaceutical company to evaluate Optimer technology

Corning launches HepGo Assay-ready 3D liver spheroid kit

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

Rapid Novor First to Decode Polyclonal Antibodies Using Only Proteomics

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Study shows CoronaVac to have high seroconversion rate after 40 days

Astodrimer sodium exhibits potent virucidal and antiviral activity against SARS-CoV-2 in vitro

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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