Infectious Diseases News and Research

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Study: Pulse oximeter devices overestimated blood oxygen levels in non-White patients with COVID-19

A retrospective analysis of over 7,000 patients with COVID-19 found that pulse oximeter devices — tools that measure oxygen levels in the blood and that are used in virtually every U.S. hospital — overestimated blood oxygen levels in non-White patients.

31 May 2022

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.

31 May 2022

Politics and pandemic fatigue doom California’s covid vaccine mandates

In January, progressive California Democrats vowed to adopt the toughest covid vaccine requirements in the country. Their proposals would have required most Californians to get the shots to go to school or work — without allowing exemptions to get out of them.

31 May 2022

Got long covid? Medical expertise is vital, and seniors should prepare to go slow

Older adults who have survived covid-19 are more likely than younger patients to have persistent symptoms such as fatigue, breathlessness, muscle aches, heart palpitations, headaches, joint pain, and difficulty with memory and concentration — problems linked to long covid.

31 May 2022

New compounds for cancer immunotherapy via STING-mediated immune activation

Innovations in cancer immunotherapy have achieved clinical success by considerably increasing the survival rate of patients undergoing cancer treatment.

31 May 2022

Study highlights clinical features and treatment approaches for human monkeypox in the UK

researchers from the UK unveil the details of imported, household, and hospital transmission of monkeypox and report the first usage of two specific antiviral agents in the treatment of this disease.

30 May 2022

Oil-based gels could make it easier for children to swallow medicines

For most children and even some adults, swallowing pills or tablets is difficult. To make it easier to give those medicines, researchers at MIT and Brigham and Women's Hospital have created a drug-delivering gel that is much easier to swallow and could be used to administer a variety of different kinds of drugs.

27 May 2022

LSHTM expert comments on the current monkeypox outbreak

Professor David Heymann, infectious disease epidemiologist at LSHTM, comments on the current monkeypox outbreak.

27 May 2022

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Researchers compared the polymer-nanoparticle hydrogel system and standard routes of delivery of broadly neutralizing antibodies against SARS-CoV-2 in a mouse model.

27 May 2022

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM).

26 May 2022

Inappropriate antibiotic prescriptions for children associated with excess health-care costs

Antibiotics inappropriately prescribed to nonhospitalized children resulted in at least $74 million in excess health-care costs in the U.S. in 2017, according to a new study from Washington University School of Medicine in St. Louis and The Pew Charitable Trusts.

26 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

Staying physically active before COVID-19 infection can help reduce disease severity

A consortium of Luxembourgish research institutions studying the national population have been looking to identify factors that may contribute to variations in severity of COVID-19 and its associated symptoms.

26 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

STIs could be prevented with a dose of doxycycline after unprotected sex

A significant proportion of bacterial sexually transmitted infections (STIs) - gonorrhea, chlamydia or syphilis - were prevented with a dose of doxycycline after unprotected sex, according to preliminary results of a clinical trial that closed early because it was very effective for men who have sex with men and transgender women who are living with HIV or are taking HIV pre-exposure prophylaxis (PrEP).

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

A research team led by Professor Kelvin Yeung Wai-kwok and Dr Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19.

25 May 2022

Study reports on the first instances of in-hospital, household transmission of monkeypox

A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious.

24 May 2022

Study reveals the persistence of neurologic symptoms among non-hospitalized COVID-19 "long-haulers"

Most non-hospitalized COVID-19 "long-haulers" at the Northwestern Medicine Neuro COVID-19 Clinic continued to experience symptoms such as brain fog, numbness and tingling, headache, dizziness, blurred vision, tinnitus and fatigue an average of 15 months after disease onset, according to a new study published in Annals of Clinical and Translational Neurology.

24 May 2022

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Across the world, food allergies are on the rise. One of the most important cells in studying this ailment are basophils, which activate inflammation and other responses to allergens such as rashes, and sometimes, anaphylaxis.

23 May 2022

Infectious Diseases News and Research

Study: Pulse oximeter devices overestimated blood oxygen levels in non-White patients with COVID-19

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Politics and pandemic fatigue doom California’s covid vaccine mandates

Got long covid? Medical expertise is vital, and seniors should prepare to go slow

New compounds for cancer immunotherapy via STING-mediated immune activation

Study highlights clinical features and treatment approaches for human monkeypox in the UK

Oil-based gels could make it easier for children to swallow medicines

LSHTM expert comments on the current monkeypox outbreak

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

Inappropriate antibiotic prescriptions for children associated with excess health-care costs

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

Staying physically active before COVID-19 infection can help reduce disease severity

The role of pyroptosis in COVID-19

STIs could be prevented with a dose of doxycycline after unprotected sex

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

Study reports on the first instances of in-hospital, household transmission of monkeypox

Study reveals the persistence of neurologic symptoms among non-hospitalized COVID-19 "long-haulers"

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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