Insulin Resistance News and Research

RSS

Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Study reveals critical molecular events in the origin of fat cells

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said.

21 Sep 2005

Significant death risk linked to airborne particles

Experts may be significantly underestimating air pollution's role in causing early death, according to a team of American and Canadian researchers, who studied two decades' worth of data on residents of the Los Angeles metro area.

20 Sep 2005

Possible new target for treating obesity and diabetes

The new target, a molecule called hVps34, is activated by amino acids (nutrients) entering the cell. This molecule triggers the activation of an enzyme, S6 Kinase 1 (S6K1), whose function UC researchers linked last year to obesity and insulin resistance.

19 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Diabetics with fatty livers could benefit from diet rich in soy protein

According to a group of researchers from Mexico they have discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes.

10 Sep 2005

Diet rich in soy protein may alleviate fatty liver

A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. The details of their findings appear in the September issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal.

6 Sep 2005

Call for closer examination of a metabolic syndrome

Two major health organizations in Europe and the United States are calling for closer examination of a syndrome that has been widely believed to predict the risk of developing heart disease, questioning whether it has been appropriately defined and whether it is in fact a syndrome at all.

25 Aug 2005

Losing weight cuts breast cancer risk

An international team of scientists has found that young women who carry a breast cancer gene, can reduce their risk of the disease by up to 65% by attaining a healthy bodyweight.

21 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said.

16 Aug 2005

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

A detectable decline in energy production by mitochondria - the organelles that are the cell's furnace for energy production - seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.

16 Aug 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

High insulin levels increase inflammatory markers and beta-amyloids

Moderately elevated levels of insulin increase the levels of inflammatory markers and beta-amyloid in plasma and in cerebrospinal fluid, and these markers may contribute to Alzheimer's disease, according to a new study posted online today from Archives of Neurology, one of the JAMA/Archives journals.

9 Aug 2005

People with prehypertension are at much higher risk of heart attack

Normal blood pressure is lower than 120/80 millimeters of mercury (mm Hg). Prehypertension is systolic blood pressure between 120 and 139 and/or diastolic pressure between 80 and 89 mm Hg. (Systolic pressure is the force in the arteries when the heart beats and diastolic pressure is the force when the heart is at rest.) Hypertension is blood pressure 140/90 mm Hg or higher.

4 Aug 2005

Visceral obesity may be an important risk factor for insulin resistance syndrome in children

Waist circumference is associated with insulin resistance in children and may offer a simple way to identify children with risk factors for cardiovascular disease and type 2 diabetes, according to a study in the August issue of Archives of Pediatrics & Adolescent Medicine.

1 Aug 2005