Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Treatment with endogenous protein can heal scarring in the lungs

The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage - and also appears to heal tissue damaged as a result of accelerated cell senescence.

27 Nov 2017

Scientists detect pathological prion protein in skin of CJD patients

Researchers have found that it was possible to detect abnormal prion protein in the skin of 23 people who died from Creutzfeldt-Jakob Disease (CJD). They also found that exposing mice to skin tissue taken from the CJD patients caused them to develop prion disease.

23 Nov 2017

Researchers question exclusion of people with prior cancer history from clinical trials

A quarter of newly diagnosed cancer patients 65 or older are survivors who had a prior cancer – often preventing them from participating in clinical trials, researchers from UT Southwestern's Simmons Cancer Center have found.

22 Nov 2017

Metabolites significantly affected in chronic kidney disease, study finds

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases.

22 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells.

22 Nov 2017

PPI use not linked to increased risk of developing dementia

Proton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD).

21 Nov 2017

Researchers develop simple test to predict T2D remission after bariatric surgery

A new simple test that helps predicts which people with type 2 diabetes will benefit most from weight loss surgery has been developed by a UCL-led team.

21 Nov 2017

Streamlined method for using CGM helps patients with diabetes maintain safe, stable glucose levels

Endocrine Society experts have developed a streamlined method for using the Dexcom G5 Mobile Continuous Glucose Monitor (CGM) to help individuals with diabetes maintain better control of their glucose levels, according to two perspectives published in the Journal of the Endocrine Society.

21 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Study: Non-vitamin K antagonist oral anticoagulants linked to reduced kidney risks

Mayo Clinic researchers have shown a link between which type of oral anticoagulant (blood-thinning medication) a patient takes to prevent a stroke and increased risks of kidney function decline or failure.

20 Nov 2017

Cancer drugs may offer new way to control high blood pressure

Drugs designed to halt cancer growth may offer a new way to control high blood pressure (hypertension), say Georgetown University Medical Center investigators.

20 Nov 2017

Amish people live longer due to mutation in blood clotting gene

Scientists have stumbled upon a genetic mutation that is found among the Indiana Amish community people that leads to impaired or defective blood clotting but predicts a longer life span for them. The study was published this week in Science Advances.

19 Nov 2017

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified a protein that can be targeted to suppress growth of a common type of breast cancer known as "estrogen receptor positive" (ER+), including ER+ cancers that are resistant to standard treatments.

17 Nov 2017

Slight changes to organ procurement system could increase number of kidney transplants

Slight changes to the system for allocating deceased-donor kidneys could result in higher rates of organ procurement and lead to more kidney transplants across the country, according to new research co-authored by an Indiana University Kelley School of Business professor.

17 Nov 2017

Majority of people do not understand link between obesity and cancer, study shows

A new study published in the Journal of Public Health has shown that the majority of people in the United Kingdom do not understand the connection between weight issues and cancer.

17 Nov 2017

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Two oxygen-producing compounds – including one that boosts performance in some laundry detergents – might one day play a key role in helping scientists successfully build a bioartificial pancreas in the lab to cure type 1 diabetes.

16 Nov 2017

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease.

15 Nov 2017

Nephrology News and Research

Further Reading

Treatment with endogenous protein can heal scarring in the lungs

Scientists detect pathological prion protein in skin of CJD patients

Researchers question exclusion of people with prior cancer history from clinical trials

Metabolites significantly affected in chronic kidney disease, study finds

Study finds specific tumor environment that stimulates cancer cells to metastasize

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

PPI use not linked to increased risk of developing dementia

Researchers develop simple test to predict T2D remission after bariatric surgery

Streamlined method for using CGM helps patients with diabetes maintain safe, stable glucose levels

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

Study: Non-vitamin K antagonist oral anticoagulants linked to reduced kidney risks

Cancer drugs may offer new way to control high blood pressure

Amish people live longer due to mutation in blood clotting gene

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

Slight changes to organ procurement system could increase number of kidney transplants

Majority of people do not understand link between obesity and cancer, study shows

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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