Therapeutics News and Research

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New understanding of wasting could lead to better treatments for infections

Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.

24 Jul 2023

Senolysis holds great promise for developing new therapeutics for cancers and age-related diseases

Announcing a new publication for Acta Materia Medica journal. The prevalence of age-related diseases has been progressively increasing worldwide.

24 Jul 2023

Arming phages with heterologous effectors paves the way for successful UTI treatment

Study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes.

24 Jul 2023

FDA head Robert Califf battles misinformation — sometimes with fuzzy facts

Robert Califf, the head of the Food and Drug Administration, doesn't seem to be having fun on the job.

24 Jul 2023

New INTREPID Alliance aims to speed up development of antivirals for future pandemics

Seven innovative pharmaceutical companies have established the INTREPID Alliance with the goal of accelerating progress in discovery and development of new antiviral treatments for future pandemics.

24 Jul 2023

Fly-to-bedside resource offers new hope for COVID-19 treatments

Millions of deaths and ongoing illnesses caused by the COVID-19 pandemic have prompted scientists to seek new ways of understanding how viruses so skillfully enter and reprogram human cells.

21 Jul 2023

Phenotype-based approach to obesity treatment shows promise

In a pilot study of 165 people, Mayo Clinic researchers looked at the effectiveness of two different approaches to weight loss: a standard lifestyle intervention and individualized therapy.

21 Jul 2023

Salk researchers uncover molecular mechanisms of HIV drug resistance

Salk Institute researchers, in collaboration with the National Institutes of Health, have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV.

21 Jul 2023

Extracellular vesicles may drive fibrosis in scleroderma

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology.

21 Jul 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

American Heart Association invests in the future of heart and brain health research

More than 100 scientists from across the U.S. are receiving special grants to support their research work in finding innovative solutions to fight heart disease and stroke.

21 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

High body temperature may boost gut microbiota to fight viral infections

Researchers from The University of Tokyo unravel the connection between high body temperature and increased viral resistance.

20 Jul 2023

Northwestern Medicine scientists discover new therapeutic target for Parkinson’s disease

Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease.

19 Jul 2023

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Have you ever wondered why some people never became sick from COVID-19? A study published today in Nature shows that common genetic variation among people is responsible for mediating SARS-CoV-2 asymptomatic infection.

19 Jul 2023

Understanding the mechanisms behind rising antifungal drug resistance

In a recent study, researchers addressed the issue of the rise of antifungal drugs-resistant infections and the advent of multidrug-resistant fungal pathogens.

19 Jul 2023

Targeted brain stimulation shows promise for treating TBI-related memory loss

Traumatic brain injury (TBI) has disabled 1 to 2% of the population, and one of their most common disabilities is problems with short-term memory. Electrical stimulation has emerged as a viable tool to improve brain function in people with other neurological disorders.

18 Jul 2023

Study establishes new link between genomic instability and bacterial protein in the urogenital tract

A team of researchers from the University of Maryland School of Maryland's (UMSOM) Institute of Human Virology (IHV), a Center of Excellence of the Global Virus Network (GVN), published new findings that emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development.

17 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

AI model accurately predicts which drugs may cause birth defects

Data scientists at the Icahn School of Medicine at Mount Sinai in New York and colleagues have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities.

17 Jul 2023

Therapeutics News and Research

New understanding of wasting could lead to better treatments for infections

Senolysis holds great promise for developing new therapeutics for cancers and age-related diseases

Arming phages with heterologous effectors paves the way for successful UTI treatment

FDA head Robert Califf battles misinformation — sometimes with fuzzy facts

New INTREPID Alliance aims to speed up development of antivirals for future pandemics

Fly-to-bedside resource offers new hope for COVID-19 treatments

Phenotype-based approach to obesity treatment shows promise

Salk researchers uncover molecular mechanisms of HIV drug resistance

Extracellular vesicles may drive fibrosis in scleroderma

Using bacteriophages to treat bladder infections

American Heart Association invests in the future of heart and brain health research

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

High body temperature may boost gut microbiota to fight viral infections

Northwestern Medicine scientists discover new therapeutic target for Parkinson’s disease

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Understanding the mechanisms behind rising antifungal drug resistance

Targeted brain stimulation shows promise for treating TBI-related memory loss

Study establishes new link between genomic instability and bacterial protein in the urogenital tract

Study sheds light on how viruses override host cell's DNA replication machinery

AI model accurately predicts which drugs may cause birth defects

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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