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Immune cells key to predicting outcomes in cancer patients, study suggests

Scientists have identified key changes in immune cells within cancerous tumors that could help improve the development of treatments.

8 Apr 2019

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidad Carlos III de Madrid, the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz have led a study which demonstrates the viability of a gene editing strategy for recessive dystrophic epidermolysis bullosa (also known as butterfly chilidren) with the tool CRISPR/Cas9 in preclinical models with this disease.

8 Apr 2019

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy.

8 Apr 2019

Gut microbiome may drive HIV transmission risk in high-risk men

Gut microbes from high HIV-risk men who have sex with men drive immune activation in mice and HIV infection in cells, according to a study published April 4 in the open-access journal PLOS Pathogens by Brent Palmer and Catherine Lozupone of the University of Colorado Anschutz, and colleagues.

8 Apr 2019

Researchers identify gut protein essential for neonatal mice to fight infections

Scientists have identified a protein critical to the immune system development and antibody production in mice, which could contribute to understanding the gut defense mechanism in infants.

8 Apr 2019

Scientists develop new imaging technology to visualize cells' eating habits

Scientists have developed a new imaging technology to visualize what cells eat, which could aid the diagnosis and treatment of diseases such as cancer.

8 Apr 2019

AVITA Medical presents results highlighting outcomes for pediatric burn patients treated using RECELL System

AVITA Medical, a global regenerative medicine company, announced that interim results describing clinical outcomes for pediatric patients treated using the RECELL System were presented at the American Burn Association 51st Annual Meeting in Las Vegas by Jeffrey Carter, MD, FACS University Medical Center New Orleans Burn Center and LSU Health New Orleans School of Medicine.

8 Apr 2019

New HIV drug that is like a "Swiss Army knife of immunotherapies"

HIV is a tricky virus that causes a unique phenomenon where the virus hides within the immune cells of patients when they are on treatment with the antiretroviral therapy (ART) drugs. When they are off the drugs, the virus comes back.

7 Apr 2019

High-dose standard radiation treatment well-tolerated by patients with centrally located NSCLC

Stereotactic Body Radiotherapy, a high-dose, precisely delivered radiotherapy, is considered the standard treatment for patients with medically inoperable, node-negative, non-small cell lung cancer.

5 Apr 2019

Researchers create online tool to determine genetic diversity and ancestry of cell lines

Cancer is a highly varied disease, with genetic differences among different tumor types, individuals and ancestral populations. These genetic differences can impact disease aggressiveness, the type of disease, and the response to therapy.

5 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

Researchers discover how specific mutation obstructs healthy blood cell maturation

In the veins, stem cells constantly mature and develop into different blood cells that are necessary for the body to work properly.

5 Apr 2019

NYU biologists develop methods to validate gene regulatory networks

A team of biologists and computer scientists has mapped out a network of interactions for how plant genes coordinate their response to nitrogen, a crucial nutrient and the main component of fertilizer.

5 Apr 2019

INTERPHEX 2019 Celebrates 40 years of Delivering Technology Innovation to Industry

INTERPHEX has been the leading pharmaceutical, biotechnology, device development, and manufacturing event for 40 years.

From Interphex 5 Apr 2019

Patients on immunotherapies should consume more fiber, fewer probiotics

A new study has found that taking probiotics could drastically reduce the response of cancer patients to immunotherapy. Patients on a fiber-rich diet showed a five-fold increase in response.

5 Apr 2019

Researchers determine atomic structure of fusion protein of a prokaryotic organism

Many viruses, including that perennial winter affliction, the influenza virus, are protected by a lipid membrane on loan from the host cell.

5 Apr 2019

Researchers identify genetic mutations that can promote regeneration after liver damage

Researchers at the Children's Medical Center Research Institute at UT Southwestern have identified genetic mutations that accumulate in the adult liver that can promote regeneration in the context of chronic liver damage.

5 Apr 2019

Magnetic nanoparticles can 'heat up' tumor cells

Unfortunately, cancer isn't simply a single disease, and some types, like pancreas, brain or liver tumors, are still difficult to treat with chemotherapy, radiation therapy or surgery, leading to low survival rates for patients.

5 Apr 2019

Study offers novel insights into how a major tumor suppressor pathway becomes deactivated

The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans.

5 Apr 2019

Study compares use of breast milk to formula in children who underwent bone marrow transplant

A new pilot study compared the use of human breast milk to formula in children less than 5 years of age who underwent bone marrow transplant (BMT), measuring the levels of inflammatory and pro-inflammatory biomarkers in the stool and blood to assess inflammatory injury to the intestinal microbiome.

5 Apr 2019

B Cell News and Research

Immune cells key to predicting outcomes in cancer patients, study suggests

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

Gut microbiome may drive HIV transmission risk in high-risk men

Researchers identify gut protein essential for neonatal mice to fight infections

Scientists develop new imaging technology to visualize cells' eating habits

AVITA Medical presents results highlighting outcomes for pediatric burn patients treated using RECELL System

New HIV drug that is like a "Swiss Army knife of immunotherapies"

High-dose standard radiation treatment well-tolerated by patients with centrally located NSCLC

Researchers create online tool to determine genetic diversity and ancestry of cell lines

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

Researchers discover how specific mutation obstructs healthy blood cell maturation

NYU biologists develop methods to validate gene regulatory networks

INTERPHEX 2019 Celebrates 40 years of Delivering Technology Innovation to Industry

Patients on immunotherapies should consume more fiber, fewer probiotics

Researchers determine atomic structure of fusion protein of a prokaryotic organism

Researchers identify genetic mutations that can promote regeneration after liver damage

Magnetic nanoparticles can 'heat up' tumor cells

Study offers novel insights into how a major tumor suppressor pathway becomes deactivated

Study compares use of breast milk to formula in children who underwent bone marrow transplant

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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