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UVA researcher wins major grant to revolutionize breast cancer treatment

A promising approach to achieve safer, more effective, and more precise breast cancer treatment has earned a University of Virginia researcher a new $5.5 million grant.

11 Apr 2025

Decoding the enzymatic breakdown of alginates for green biotechnology

Every year, thousands of tonnes of brown algae are extracted from the seabed to obtain compounds such as alginates, a polymer composed of sugars that has high density and strength, offering potential biotechnological applications.

11 Apr 2025

COVID-19 treatments show minimal serious side effects

Numerous treatment options for COVID-19 have been approved by the U.S. Food and Drug Administration over the last four years, including antiviral drugs and monoclonal antibodies that suppress an excessive immune response.

11 Apr 2025

GSK3β identified as a driver of drug resistance in BRAF mutant melanoma

A new research perspective was published in Oncotarget, Volume 16, on April 4, 2025, titled "GSK3β activation is a key driver of resistance to Raf inhibition in BRAF mutant melanoma cells."

11 Apr 2025

GLP-1 agonists may reshape the gut microbiome

Research reveals GLP-1 receptor agonists influence gut microbiome, enhancing metabolic health and offering anti-inflammatory benefits for diabetes management.

11 Apr 2025

Probiotics improve emotional state in healthy adults, study finds

A randomized controlled trial in 88 healthy adults found that probiotics reduced negative mood when assessed using daily self-reports, though traditional questionnaires failed to detect significant changes. These findings suggest that daily mood tracking may offer a more sensitive way to capture subtle emotional effects of probiotics in non-clinical populations.

10 Apr 2025

Researchers explore drug repurposing strategy for Parkinson's disease

Despite significant advances in Parkinson's disease (PD) treatment, it remains incurable, with limited therapeutic options.

10 Apr 2025

Alcohol reshapes reward learning differently in male and female rats

Chronic alcohol exposure causes lasting impairments in decision-making in male rats, altering how the brain processes reward-based learning. A new study reveals sex-specific neural changes in the striatum, with female rats showing resilience despite altered brain activity.

10 Apr 2025

RFK Jr.’s purge of FOIA staff at FDA Spares people working on covid vaccine lawsuits

Mass firings at the FDA have decimated divisions tasked with releasing public records generated by the agency's regulatory activities in sectors including tobacco, food, medical devices, and veterinary medicine.

10 Apr 2025

KFF Health News' 'What the Health?': The dismantling of HHS

A week into the reorganization of the Department of Health and Human Services announced by Secretary Robert F. Kennedy Jr., the scope of the staff cuts and program cutbacks is starting to become clear.

10 Apr 2025

Can psychedelics break compulsive eating habits in obesity?

A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.

10 Apr 2025

New quinoline-based antiviral shows strong promise against SARS-CoV-2

Researchers develop quinoline-based drug with inhibitory activity against the SARS-CoV-2 papain-like protease (PLpro).

10 Apr 2025

Sylvester Cancer Center launches clinical trial for patients with high-grade neuroendocrine tumors

A clinical trial for patients with high-grade neuroendocrine tumors is now open for enrollment at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

9 Apr 2025

Largest study of osteoarthritis genetics uncovers new drug targets

Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

9 Apr 2025

Study shows minimal lean muscle mass loss with GLP-1 and GLP-1/GIP therapy for weight loss

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that patients using GLP-1 or combined GLP-1 / GIP receptor agonist therapy for weight loss experienced minimal lean muscle mass loss as they lost weight across 6 months of treatment.

9 Apr 2025

Oklahoma Children's Hospital improves care for babies with neonatal abstinence syndrome

In years past, health care providers took a punitive stance toward women giving birth to babies exposed to substances like opioids in the womb.

9 Apr 2025

Protein linked to Parkinson's also found to drive melanoma growth

A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.

9 Apr 2025

High fiber diet helps protect against dangerous gut infections

A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria.

9 Apr 2025

Scientists stop long-COVID symptoms in mice using a new antiviral compound

Australian scientists developed a novel antiviral that targets the SARS-CoV-2 PLpro enzyme, showing strong preclinical efficacy in reducing both acute and long COVID symptoms in mice.

9 Apr 2025

ETH Zurich researchers identify redundancies between the genes involved in DNA repair

Researchers aThe DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information.t ETH Zurich have unraveled the complex network that cells use to repair their genetic material.

9 Apr 2025