Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

New research finds molecular link between obesity and diabetes

Researchers say they have discovered a molecular link between obesity and type 2 diabetes, and the link could be a potential target for new drugs to treat the disease.

21 Jul 2005

Heart attack patients: shedding pounds reduces risks

Heart attack patients with diabetes or a cluster of cardiovascular risk factors known as metabolic syndrome have an increased risk of another heart attack, stroke or death, but patients who lost weight after their heart attacks were less likely to become diabetic, according to a new study in the July 19, 2005, issue of the Journal of the American College of Cardiology.

21 Jul 2005

Protein found in fat cells is a newly discovered cause of insulin resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2 diabetes and offering a potential new target for the development of drugs to treat diabetes.

20 Jul 2005

Insulin resistance increases a person's risk for development of congestive heart failure

Congestive heart failure (CHF) is a major cause of illness and death, according to background information in the article. The death rate for patients with CHF is 4 to 8 times that of the general population. The predominant causes of heart failure are hypertension and coronary heart disease.

19 Jul 2005

Insulin keeps fat in the liver under control

Insulin, a hormone long recognized as a generator of fat, also keeps fat in the liver under control, according to a new study in the July issue of Cell Metabolism.

19 Jul 2005

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Scientists in France and the United States report that a variant of a common protein plays a primary role in Type 2 diabetes and obesity, key features of the "insulin resistance syndrome" that affects more than 50 million people in this country and a similar number in Europe.

19 Jul 2005

Scientists have identified a gene associated with both childhood and adult obesity

According to research published today in Nature Genetics, the team from Imperial College London, Hammersmith Hospital, London, and the CNRS Lille, France, have identified a gene (ENPP1), with strong links to childhood obesity in 3,147 in a sample of 4,886 French Caucasian individuals.

18 Jul 2005

Low dose birth control pill raises heart attack risk, especially in some women

A new review suggests that low-dose birth control pills, which are generally considered to be safer than the pill of the past, still carries an increased risk for heart attack and stroke.

11 Jul 2005

Fat adults more likely to have increased insulin resistance, a risk marker for Type 2 diabetes

Adult lifestyle has more influence on your chances of developing diabetes than childhood experience, according to new research whose findings contradict previously-held beliefs.

6 Jul 2005

Takeda Pharmaceuticals submits NDA for a new oral diabetes medication

Takeda Pharmaceuticals North America today announced that the company has submitted a New Drug Application (NDA) for a new oral medication that combines pioglitazone HCl and glimepiride, a sulfonylurea, to the United States Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

30 Jun 2005

Major study says for diabetics with high blood pressure diuretics are the best option

A major new study has found that for people with type 2 diabetes and high blood pressure, cheaper diuretic medications may be the most cost-effective option in reducing hypertension.

29 Jun 2005

Exercise helps find genetic regions linked to prediabetes

People's bodies respond to exercise in different ways, and their genetic makeup is partly responsible.

28 Jun 2005

Insulin resistance drug with anti-inflammatory effects reduces risk factors

A drug, which reduces insulin resistance and also may have anti-inflammatory and other effects on blood vessels, lowered cardiovascular risk factors in patients with diabetes more than another diabetes medicine, even though both drugs improved blood sugar control equally, according to a new study (PDF) in the June 21, 2005, issue of the Journal of the American College of Cardiology.

21 Jun 2005

Research suggests that children with a neuropsychiatric disease may be at risk for type 2 diabetes, and vice versa

As many as one in five children with newly diagnosed type 2 diabetes may also have a neuropsychiatric disorder, according to a new study. The illnesses include depression, attention-deficit hyperactivity disorder, autism, developmental delay, schizophrenia, and bipolar disorder.

20 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Diabetic retinopathy has been found in nearly 8 percent of pre-diabetic participants in the Diabetes Prevention Program (DPP), according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Researchers describe emerging strategy for prevention, early treatment of Type 2 diabetes

Type 2 diabetes may be significantly delayed or prevented through medication that takes the load off of the body's delicate insulin-producing cells, according to a study released today by researchers at the Keck School of Medicine of the University of Southern California.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Latest research on men's health issues, treatments and lifestyle practices

Today, leading researchers are gathering at the annual meeting of The Endocrine Society in San Diego to present the latest research on men's health issues, treatments and lifestyle practices. New findings could help doctors identify risks and treat men's conditions more effectively.

6 Jun 2005

Steroid treatment for prematurity put to the test

Babies whose mothers received steroid injections before giving birth have no higher risk of heart disease at age 30 than those whose mothers received a placebo treatment.

30 May 2005