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New drug 'ubrogepant' may work for migraine

A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.

19 Nov 2019

Study shows how a potent psychedelic changes our waking brain waves

Scientists have peered inside the brain to show how taking DMT affects human consciousness by significantly altering the brain's electrical activity.

19 Nov 2019

Nutraceuticals could help prevent diabetes

Diabetes mellitus is among the fastest-growing conditions in the world, and in Australia, a new case is diagnosed every 5 minutes. Many people with this illness are now taking diet supplements in an attempt to prevent this condition.

17 Nov 2019

Clinical trial: Oral drug improves exercise capacity in teens with congenital heart defects

The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe, congenital single-ventricle heart defects.

17 Nov 2019

Experimental drug found to be effective at reducing bad cholesterol

Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients already taking the maximum dose of statin drugs, according to data of the ORION-10 trial presented Saturday, Nov. 16, at the American Heart Association's Scientific Sessions 2019.

17 Nov 2019

Study shows link between inflammation and mental sluggishness

Scientists at the University of Birmingham in collaboration with the University of Amsterdam have uncovered a possible explanation for the mental sluggishness that often accompanies illness.

15 Nov 2019

New treatment stops peanut allergy for 6 weeks with single dose

A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.

14 Nov 2019

Targeting the formation of alpha-synuclein aggregates may slow Parkinson's progression

Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease.

13 Nov 2019

Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

Young male cancer survivors may benefit from testosterone replacement therapy

Young male cancer survivors may significantly benefit from testosterone replacement therapy - especially after testicular cancer - according to the first ever clinical trial of its kind.

12 Nov 2019

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.

11 Nov 2019

Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis.

11 Nov 2019

Opioids do not improve quality of life or depression in OA patients

New research presented at the 2019 ACR/ARP Annual Meeting suggests that opioids contribute no measurable benefit to quality of life or depression for patients with osteoarthritis (OA).

11 Nov 2019

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis.

11 Nov 2019

Dengue vaccine from Takeda shows promise

Officials have confirmed the initial success with trials of Dengue vaccine. Dengue, a viral disease borne by mosquitoes is considered to be one of the top ten health threats says the world Health Organization (WHO). Since the beginning of the outbreaks and the hundreds of deaths due to this infection, researchers have been on the lookout for vaccines to prevent this infection.

10 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Supplements of vitamin D and omega-3 fatty acids (often sold as fish oil) do not help people with type 2 diabetes stave off chronic kidney disease, according to findings from the largest clinical study to date of the supplements in this patient population.

10 Nov 2019

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

10 Nov 2019

Big data provide opportunity for research, drive learning at the healthcare system level

ISPOR, the professional society for health economics and outcomes research - held its third plenary session at ISPOR Europe 2019, "Big Data Healthcare: Endless Opportunities for Research and Learning," this morning in Copenhagen, Denmark.

7 Nov 2019

Placebo News and Research

New drug 'ubrogepant' may work for migraine

Study shows how a potent psychedelic changes our waking brain waves

Nutraceuticals could help prevent diabetes

Clinical trial: Oral drug improves exercise capacity in teens with congenital heart defects

Experimental drug found to be effective at reducing bad cholesterol

Study shows link between inflammation and mental sluggishness

New treatment stops peanut allergy for 6 weeks with single dose

Targeting the formation of alpha-synuclein aggregates may slow Parkinson's progression

Russian scientists explain how an additional component can triple vaccine efficiency

Young male cancer survivors may benefit from testosterone replacement therapy

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

Methotrexate reduces joint damage in hand osteoarthritis

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Opioids do not improve quality of life or depression in OA patients

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

Dengue vaccine from Takeda shows promise

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

Big data provide opportunity for research, drive learning at the healthcare system level

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