Immune System News and Research

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Using models to understand malaria

Malaria is one of the world's major killers. More than 500 million people live in epidemic regions and some 2 million - mostly children - die each year. And each year, drug resistance increases in the malarial parasite, Plasmodium falciparum, and the search for new treatments becomes more desperate.

12 Jan 2005

Important clue to understanding the origins of the AIDS epidemic

Medical Research Council (MRC) scientists have uncovered an important clue to understanding the origins of the AIDS epidemic. The work suggests that harnessing natural mechanisms of resistance to HIV infection might provide new methods for combating AIDS.

12 Jan 2005

Safety established for Vaxin's first flu vaccine in clinical trial

Vaxin Inc., a privately-held biotechnology company, has demonstrated, in a Phase I human clinical study, that the company's recombinant influenza vaccine provides a potential alternative to traditional flu vaccines.

12 Jan 2005

Novel vaccine that uses immune cells as factories to produce Her2/neu protein may offer a way to treat some breast cancers

Based on successful animal studies, a novel vaccine that uses immune cells as factories to produce Her2/neu protein may offer a way to treat some human breast cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.

10 Jan 2005

Important clue to understanding the origins of the AIDS epidemic

10 Jan 2005

Potential new therapies for cancer and bleeding disorders

Lexicon Genetics announced today that it has advanced two of its drug discovery programs into preclinical development in preparation for investigational new drug (IND) applications.

10 Jan 2005

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Millennium Pharmaceuticals today announced, in collaboration with Johnson & Johnson Pharmaceutical Research & Development, LLC, the initiation of VISTA (Velcadeas Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone), a multicenter, international phase III clinical trial of Velcadein combination with melphalan and prednisone versus melphalan and prednisone in patients with newly diagnosed multiple myeloma (MM) who are not transplant candidates.

10 Jan 2005

Key genetic factor determines HIV/AIDS risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID).

10 Jan 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B

Results from a large international clinical study reported in this week's issue of The Lancet showed that peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B. The investigator-initiated study is the largest clinical trial to date with peginterferon alfa-2b therapy for chronic hepatitis B.

7 Jan 2005

Discovery could lead to a screening test that identifies people who have a higher or lower susceptibility to HIV/AIDS

6 Jan 2005

DermaVir, a novel treatment for HIV/AIDS, complements and improves present drug therapies

DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys.

6 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Stem cells from umbilical cord blood effectively treated heart attacks

When injected into rats' hearts soon after a heart attack, stem cells taken from human umbilical cord blood (HUCB) greatly reduced the size of heart damage and restored pumping function to near normal. This improvement occurred without the need for drugs to prevent the rats' immune system from rejecting the human cells.

5 Jan 2005

Chamomile tea shown to boost the immune system and fight infections associated with colds

For centuries, people who’ve felt sick or stressed have tried drinking chamomile tea as a medicinal cure-all. Now, researchers in England have found new evidence that the popular herbal tea may actually help relieve a wide range of health ailments, including colds and menstrual cramps.

5 Jan 2005

New technique could lead to more effective therapies for AIDS

When researchers came up with the powerful cocktail of anti-HIV drugs known as highly active antiretroviral therapy (HAART), they hoped they had found a way to finally rid the body of the virus. But they were wrong.

4 Jan 2005

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

High levels of a blood protein called mannose-binding lectin (MBL) are associated with lower risk of heart attack, particularly among diabetics, report Saevardottir and colleagues.

28 Dec 2004

AIDS breakthrough - vaccine strengthens the body’s immune system againts HIV

A Hadassah University Medical Center research team has developed a vaccine that significantly strengthens the body’s immune system against the autoimmune sequela of HIV infection, a breakthrough that could dramatically make an impact in the treatment of AIDS patients.

28 Dec 2004

Research animals experience severe stress response at slightest contact with researchers

Mice, rabbits, rats, beagles, geese, and other animals all show measurable physiological stress responses to routine laboratory procedures that have been up until now viewed as relatively benign.

28 Dec 2004

Immune System News and Research

Using models to understand malaria

Important clue to understanding the origins of the AIDS epidemic

Safety established for Vaxin's first flu vaccine in clinical trial

Novel vaccine that uses immune cells as factories to produce Her2/neu protein may offer a way to treat some breast cancers

Important clue to understanding the origins of the AIDS epidemic

Potential new therapies for cancer and bleeding disorders

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Key genetic factor determines HIV/AIDS risk

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B

Discovery could lead to a screening test that identifies people who have a higher or lower susceptibility to HIV/AIDS

DermaVir, a novel treatment for HIV/AIDS, complements and improves present drug therapies

New hope for millions of patients suffering from liver damage (cirrhosis)

Stem cells from umbilical cord blood effectively treated heart attacks

Chamomile tea shown to boost the immune system and fight infections associated with colds

New technique could lead to more effective therapies for AIDS

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

AIDS breakthrough - vaccine strengthens the body’s immune system againts HIV

Research animals experience severe stress response at slightest contact with researchers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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