Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study: Subconscious changes in day-to-day movements can predict Alzheimer’s disease

As people go about their daily activities, complex fluctuations in their movement occur without conscious thought. These fluctuations -- known as fractal motor activity regulation (FMAR) -- and their changes are not readily detectable to the naked eye, but FMAR patterns can be recorded using a wristwatch-like device known as an actigraph.

23 Jun 2021

New project aims to identify quantitative biological features common across diseases

Building on the success of innovative research by the PRISM project, the Innovative Medicine Initiative 2, a joint undertaking between the EU and the European Federation of Pharmaceutical Industries and Associations (EFPIA), has backed the program with funding for a new project to explore the underlying biology of Alzheimer's disease, schizophrenia and Major Depressive Disorder (MDD).

23 Jun 2021

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

The most comprehensive molecular study to date of the brains of people who died of COVID-19 turned up unmistakable signs of inflammation and impaired brain circuits.

22 Jun 2021

Research findings on the links between air pollution and neurodegeneration

There is growing awareness that air pollutants are playing a critical role in the development of neurodegenerative diseases.

22 Jun 2021

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

By the time people with Alzheimer's disease start exhibiting difficulty remembering and thinking, the disease has been developing in their brains for two decades or more, and their brain tissue already has sustained damage. As the disease progresses, the damage accumulates, and their symptoms worsen.

21 Jun 2021

Investigational Alzheimer's drug reduces molecular markers of the disease

An investigational Alzheimer's drug reduced molecular markers of disease and curbed neurodegeneration in the brain, without demonstrating evidence of cognitive benefit, in a phase 2/3 clinical trial led by researchers at Washington University School of Medicine in St. Louis through its Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU).

21 Jun 2021

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias?

21 Jun 2021

KHN’s ‘What the Health?’: The ACA lives

For the third time in nine years, the Affordable Care Act has survived a constitutional challenge at the Supreme Court. In a 7-2 decision, the court ruled that the states and individuals who filed the latest challenge lacked standing to sue.

18 Jun 2021

First insights into human prion disease could help tackle neurodegenerative diseases

Surface features of human prions have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases.

18 Jun 2021

Controlling brain state transitions using a molecule responsive to light

A study led by researchers from IBEC and IDIBAPS achieves, for the first time, the control of brain state transitions using a molecule responsive to light, named PAI.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions - misfolded proteins that cause lethal incurable diseases - have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain's emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio and collaborating institutions suggests.

17 Jun 2021

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

\A team of SMU biological scientists has confirmed that P-glycoprotein (P-gp) has the ability to remove a toxin from the brain that is associated with Alzheimer's disease.

16 Jun 2021

Researchers report on the role of brain cell membranes' lipids in Alzheimer's progression

Alzheimer's disease is predominant in elderly people, but the way age-related changes to lipid composition affect the regulation of biological processes is still not well understood.

15 Jun 2021

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

The Southwest National Primate Research Center at Texas Biomedical Research Institute has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026.

15 Jun 2021

Novel biomarker effectively detects Alzheimer's disease before symptoms emerge

A newly developed radiotracer can measure increases in brain tau at least a year prior to the emergence of other symptoms.

15 Jun 2021

Study creates a new model of Alzheimer's disease progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual neuronal death, but little is known about how other cells in the brain react during disease progression.

14 Jun 2021

Alzheimer's Disease News and Research

Further Reading

Study: Subconscious changes in day-to-day movements can predict Alzheimer’s disease

New project aims to identify quantitative biological features common across diseases

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

Research findings on the links between air pollution and neurodegeneration

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

Investigational Alzheimer's drug reduces molecular markers of the disease

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

KHN’s ‘What the Health?’: The ACA lives

First insights into human prion disease could help tackle neurodegenerative diseases

Controlling brain state transitions using a molecule responsive to light

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

Researchers report on the role of brain cell membranes' lipids in Alzheimer's progression

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

Novel biomarker effectively detects Alzheimer's disease before symptoms emerge

Study creates a new model of Alzheimer's disease progression

Researchers study what happens in brain cells affected by Alzheimer's disease

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Super-resolution imaging technique could enable early detection of neurological disorders

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