Inflammation News and Research

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E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

10 Feb 2025

Research highlights gender and age differences in eye gene therapy responses

Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found.

10 Feb 2025

Novel MSC-based therapy provides hope for ocular GVHD treatment

Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the donor's immune cells attack the recipient's tissues.

10 Feb 2025

Study reveals link between traumatic experiences and endometriosis risk

The study finds a connection between trauma and endometriosis, suggesting that addressing psychological factors could improve diagnosis and treatment outcomes.

10 Feb 2025

Microplastics in food packaging may increase heart disease risk

Microplastics pose a threat to heart health, causing harmful changes in vascular cells and increasing the risk of cardiovascular diseases like atherosclerosis.

10 Feb 2025

Study examines how diet impacts gene expression in fat tissue

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

8 Feb 2025

New mechanism regulates the immune response against parasites

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites.

8 Feb 2025

Living in disadvantaged areas reduces ALS survival time by over 30%

Living in a disadvantaged community may decrease the length of time a person can survive with amyotrophic lateral sclerosis, or ALS, by over 30%, a Michigan Medicine-led study suggests.

7 Feb 2025

Vision loss risks in patients using popular GLP-1 medications raise concerns

A small percentage of patients taking the extraordinarily popular GLP-1 medications have experienced vision problems, but a direct causal link with the drugs has not been established. That is the conclusion of a retrospective study published online on Jan. 30 in JAMA Ophthalmology.

7 Feb 2025

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

7 Feb 2025

Gut microbiome shifts from sugary drinks tied to higher diabetes risk

Researchers examine the association between sugar-sweetened beverage intake and gut microbiota-mediated changes that may mitigate the risk of diabetes.

7 Feb 2025

Early immune system changes contribute to lung damage in cystic fibrosis

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the disease causes changes in the immune system early in life, presumably even in newborns.

7 Feb 2025

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer's disease

In a groundbreaking theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer's disease.

6 Feb 2025

Research unveils synergistic effects of tau and beta-amyloid in Alzheimer's

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's-tau protein and beta-amyloid-affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions.

6 Feb 2025

New method for detecting inflammation could revolutionize disease diagnosis

Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.

6 Feb 2025

Brazilian study reveals new pathways for preventing atrial fibrillation

A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and treating atrial fibrillation, a condition that significantly raises the risks of stroke and dementia.

6 Feb 2025

Granzyme K identified as key trigger of complement system in autoimmune diseases

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that patrols our body, ever vigilant for signs of infection or injury

6 Feb 2025