Proliferation News and Research

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Epidemiologist to advance research on hormonal markers for better prediction of breast cancer risk

Epidemiologist Susan Hankinson at the University of Massachusetts Amherst has received a five-year, $4.2 million grant from the National Cancer Institute to build upon and advance her research group's earlier work to identify and validate hormonal markers to better predict the risk of invasive breast cancer in postmenopausal women.

19 Sep 2017

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

The discovery of a mechanism by which normal brain cells regulate the expression of the NFIA gene, which is important for both normal brain development and brain tumor growth, might one day help improve therapies to treat brain tumors. The study appears in the journal Nature Neuroscience.

13 Sep 2017

MGH researchers identify potential strategy for improving efficacy of angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a potential strategy for improving the efficacy of angiogenesis inhibitors, drugs that help fight cancer by blocking the formation of new blood vessels.

13 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes.

4 Sep 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

New blood vessels branch out of preexisting ones is via a process called angiogenesis. Although this is essential for survival, development and wound healing, on the flip side, it also feeds and progresses malignant tumors, as well as other diseases.

29 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017

Study shows previously unknown dimension of lymphangiogenesis during worm infection

Lymph nodes are small, kidney-shaped organs found throughout the body. Full of immune cells, their function is to clear out foreign objects and support the immune system.

28 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

Research paves way for new drugs that may prevent tumor repopulation after radiation therapy

Whenever an organism is damaged, the cells surrounding the wound receive signals to proliferate more intensely so as to regenerate the injured tissue.

26 Aug 2017

Study identifies promising drug candidate for treating demyelinating diseases

Brain functions are maintained by the neural network. Neural network is formed by the connection between the neurite, and this connection is supported by the wrapping of myelin.

26 Aug 2017

Bacterial infections may trigger dysregulation of blood formation

It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout an individual's lifetime, are also able to respond to the infection.

24 Aug 2017

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Through their pattern of firing, neurons influence the behavior of the cells that upon maturation will provide insulation of neuronal axons, according to a new study publishing 22 August in the open access journal PLOS Biology by Balint Nagy, Maria Kukley and colleagues at the University of Tübingen, Germany.

23 Aug 2017

Mayo Clinic researchers discover new cause of treatment resistance in prostate cancer

Mayo Clinic researchers have identified a new cause of treatment resistance in prostate cancer. Their discovery also suggests ways to improve prostate cancer therapy. The findings appear in Nature Medicine.

14 Aug 2017

Study provides promising framework to anticipate drug resistance in cancer

Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

NYITCOM research could potentially lead to more effective, less toxic cancer treatment

Patients undergoing conventional chemotherapy for certain cancers could potentially receive more effective and less toxic drug treatment.

9 Aug 2017

Researchers demonstrate potential of new PET tracer for imaging prostate cancer

In the featured translational article in the August issue of The Journal of Nuclear Medicine, researchers at the University of Michigan demonstrate the potential of a new PET tracer, Carbon-11 labeled sarcosine (11C-sarcosine), for imaging prostate cancer, and set the stage for its possible use in monitoring other cancers.

7 Aug 2017

Proliferation News and Research

Epidemiologist to advance research on hormonal markers for better prediction of breast cancer risk

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

MGH researchers identify potential strategy for improving efficacy of angiogenesis inhibitors

Seeing the full picture, real-time analysis of live-cells

Study describes link between key melanoma signaling pathway and novel class of drugs

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

FDA approves first cell-based gene therapy for use in the United States

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

Targeting bone marrow protein could be effective way to improve stem cell transplants

Study shows previously unknown dimension of lymphangiogenesis during worm infection

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Research paves way for new drugs that may prevent tumor repopulation after radiation therapy

Study identifies promising drug candidate for treating demyelinating diseases

Bacterial infections may trigger dysregulation of blood formation

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Mayo Clinic researchers discover new cause of treatment resistance in prostate cancer

Study provides promising framework to anticipate drug resistance in cancer

Counteracting premature aging

NYITCOM research could potentially lead to more effective, less toxic cancer treatment

Researchers demonstrate potential of new PET tracer for imaging prostate cancer

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

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