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Amprologix wins £1.2 million contract to tackle antimicrobial-resistant MRSA

Amprologix Limited, a University of Plymouth spinout company, has won a £1.2 million contract from the Department for Health and Social Care to accelerate development and scale up its lead antibiotic candidate to tackle antimicrobial resistant MRSA and related superbugs.

4 Feb 2019

New research uncovers crucial link between polyamines and MYCN

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.

4 Feb 2019

Salk researchers pin down why some patients don't respond to common antidepressants

The most commonly prescribed antidepressants, selective serotonin reuptake inhibitors, lift the fog of depression for many people. But for around a third of people with major depressive disorder, SSRIs don't make much of a difference.

1 Feb 2019

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

SCYNEXIS, Inc., a biotechnology company delivering innovative therapies for difficult-to-treat and often life-threatening infections, today announced positive results from the first interim efficacy analysis of the ongoing FURI study.

1 Feb 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

Unexpected link found between natural contaminants and manmade pollutants

Scientists are a step closer to understanding what controls fine particulate matter in the Earth's atmosphere after identifying new linkages between natural contaminants and with manmade pollutants.

31 Jan 2019

WPI researchers use brain imaging to enhance personal learning environments

Could a computer detect a person's emotions? Could it tell when someone is frustrated over something like a tricky math problem on an online tutoring program? Could it detect deep reflection on a problem? A research team led by Worcester Polytechnic Institute computer science assistant professor Erin Solovey is working to develop a system that could extract that information by merging computer science with neuroscience.

31 Jan 2019

Expediting HPLC Method Development in Pharmaceutical Analysis

In this interview, Michael Dong discusses stability-indicating methods such as UHPLC, in pharmaceutical analysis. At Pittcon, Michael will introduce a 3-pronged template approach to HPLC method development.

From Pittcon 30 Jan 2019

New project will develop biomarker-based system to send personalized advice on dietary, lifestyle habits

The PREVENTOMICS European project will develop, from this November and for 3 years, personalized plans for nutrition and lifestyle habits to improve the health of people, based on individual traits such as physical and behavioral traits, lifestyle, genotype, preferences and physical condition.

29 Jan 2019

Annual RegenMed SA Conference to focus on future of stem cells

Doctors regularly perform stem cell transplants, also known as bone marrow transplants, to replace cells damaged by chemotherapy.

29 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Hens that lay human proteins in eggs offer cost-effective method of producing new drugs

Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain types of drugs, research suggests.

28 Jan 2019

Investigational Ebola treatment found to be safe in adults

The investigational Ebola treatment mAb114 is safe, well-tolerated, and easy to administer, according to findings from an early-stage clinical trial published in The Lancet.

25 Jan 2019

CMV vaccine provides a new way to fight malaria

Early research on a new approach to protecting against malaria is offering promising, potentially long-lasting results against the persistent parasite that sickens hundreds of millions people each year.

24 Jan 2019

Study sheds new light on male infertility

Hope has emerged for infertile men as scientists at Newcastle University have understood the importance of a gene in regulating the production of fully-functioning sperm.

24 Jan 2019

Cardiovascular disease risk begins even before birth

Heart disease is the greatest killer in the world today, and it is widely accepted that our genes interact with traditional lifestyle risk factors, such as smoking, obesity and/or a sedentary life to promote an increased risk of cardiovascular disease.

23 Jan 2019

Nicotinamide riboside supplementation confers significant physiological benefits to mothers and offspring

ChromaDex Corp. today reported that results of a first-of-a-kind preclinical study on lactation have shown that supplementation with the unique B3 vitamin nicotinamide riboside confers significant and enduring physiological benefits to mothers and offspring.

23 Jan 2019

Lab-Scale Clarification of Mammalian Cell Cultures Expressing Recombinant Antibodies

Tina Stoschek and Marcus Gerlach discuss maximizing mAb generation using lab-scale clarification of cell cultures expressing recombinant antibodies.

From Sartorius 23 Jan 2019

Mount Sinai joins with Paradigm and ReqMed to repurpose drug for treatment of MPS

The Icahn School of Medicine at Mount Sinai has entered into two exclusive licenses to develop the drug pentosan polysulfate sodium for and ReqMed Company, Ltd. of Japan.

21 Jan 2019

QIAGEN receives first companion diagnostic approval in Japan

QIAGEN N.V. today announced that the Japanese Pharmaceuticals and Medical Device Agency has approved the therascreen EGFR RGQ PCR Kit to allow its use as a companion diagnostic with Pfizer's VIZIMPRO (dacomitinib) for EGFR gene mutation-positive, inoperable or recurrent non-small cell lung cancer.

17 Jan 2019