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Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Aging reduces the risk of developing genetically related diseases

Unexpected findings provide insights into how aging and genetically determined diseases are associated.

26 Aug 2021

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

In a study in mice, Johns Hopkins Medicine researchers have found that the smooth muscle cells lining the walls of blood vessels can lose their elasticity and lead to vascular stiffening, a condition that can precede heart disease and stroke.

26 Aug 2021

Motor control in older adults may be exacerbated by age-related executive functioning decline

Aging-US published "Cognition and action: a latent variable approach to study contributions of executive functions to motor control in older adults" which reported that Aging is associated with profound alterations in motor control that may be exacerbated by age-related executive functioning decline.

26 Aug 2021

Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Wake Forest School of Medicine and the American Federation for Aging Research have received a renewal award for up to $5 million over five years from the National Institute on Aging, National Institutes of Health, to continue their management of the Research Centers Collaborative Network.

25 Aug 2021

Young adults with ADHD 69% more likely to have had a substance use disorder

Half of adults aged 20-39 with attention deficit hyperactivity disorder (ADHD) have had a substance use disorder (SUD) in their lifetime according to new research published online ahead of print this month in Alcohol and Alcoholism.

25 Aug 2021

Researchers identify numerous genetic regions that may affect individuals' food intake

A team of researchers at Massachusetts General Hospital, Boston University School of Public Health, and other institutions have identified more than two dozen genetic regions that may affect individuals' food intake.

25 Aug 2021

Study focuses on understanding how muscle fatigue and changes in gait affect older adults

Older adults on a walk or hike, or just going about their daily routines, seem to experience greater fatigue than their younger counterparts. Such fatigue may ultimately affect their ability to participate in activities that are meaningful to them and help keep them healthy.

25 Aug 2021

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

New information from a study reported on in STEM CELLS might result in more effective treatments for osteoarthritis and other cartilage diseases, as well as hereditary disorders affecting cartilage development.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Researchers at Albert Einstein College of Medicine and the City University of New York Graduate School of Public Health and Health Policy have been awarded a five-year, $14.5 million grant from the National Institutes of Health to continue leading and expand their research on HIV treatment and care in five Central African nations.

24 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Analysis of medical data from around 1800 65-year-old residents of Kobe, a large Japanese city, has shown that at least 3% have possible sarcopenia (*1), revealing that the risks are higher in those who are underweight and don't exercise enough.

24 Aug 2021

Study identifies a novel potential biomarker for hepatocellular carcinoma

Aging-US published "Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma" which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA network in hepatocellular carcinoma.

23 Aug 2021

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Amyloid plaques are protein deposits that collect between brain cells, hindering function and eventually leading to neuronal death.

23 Aug 2021

Preclinical study validates crucial role of the spleen in cardiac repair

Although we can survive without a spleen, evidence continues to mount that this abdominal organ plays a more valuable role in our physiological defenses than previously suspected.

23 Aug 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

Aging News and Research

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Aging reduces the risk of developing genetically related diseases

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

Motor control in older adults may be exacerbated by age-related executive functioning decline

Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Young adults with ADHD 69% more likely to have had a substance use disorder

Researchers identify numerous genetic regions that may affect individuals' food intake

Study focuses on understanding how muscle fatigue and changes in gait affect older adults

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Study identifies a novel potential biomarker for hepatocellular carcinoma

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Preclinical study validates crucial role of the spleen in cardiac repair

Study investigates the effects of calycosin on breast cancer cell progression

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

After pandemic ravaged nursing homes, new state laws protect residents

Biden’s no-jab-no-job order creates quandary for nursing homes

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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