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Early management of gestational diabetes can prevent maternal and child health complications

Speaking at the American Diabetes Association 84th Scientific Sessions, authors of a new Lancet Series challenge current approaches to managing gestational diabetes (a type of diabetes that can be diagnosed during pregnancy) and call for initiating treatment much earlier to prevent complications during pregnancy and beyond.

19 Jun 2024

Researchers propose a 'protein aggregation clock' to measure aging and health

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure ageing and health in a new perspective article published in Nature Cell Biology.

19 Jun 2024

Mental well-being crucial for healthy aging, new study reveals

A study in Nature Human Behavior found that mental well-being has a causal effect on healthy aging, independent of socioeconomic status, with better mental health linked to improved aging outcomes.

18 Jun 2024

Rutgers Health study reveals key factors in hospice discharges leading to negative outcomes

Black patients who leave hospice care and patients with short stays in hospice care are at increased risks for being admitted to a hospital after being discharged from hospice, according to Rutgers Health researchers.

18 Jun 2024

Nicotinamide riboside boosts walking endurance in peripheral artery disease

The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

18 Jun 2024

Gprc5a identified as potential drug target for treating osteoporosis

Osteoporosis is a skeletal condition that leads to the weakening of bones, making them porous, fragile, and prone to breakage.

18 Jun 2024

Older women are different than older men. Their health is woefully understudied.

Medical research has shortchanged women for decades. This is particularly true of older women, leaving physicians without critically important information about how to best manage their health.

18 Jun 2024

Open-access atlas unveils the molecular mechanisms of roundworm aging

A new aging atlas gives scientists an in-depth view of how individual cells and tissues in worms age and how different lifespan-extending strategies might stop the clock.

18 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

How ketone bodies contribute to brain health and memory preservation

The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice.

17 Jun 2024

Protein aggregation: A new frontier in age-related disease detection

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure aging and health in a new perspective article published in Nature Cell Biology.

17 Jun 2024

Study reveals diverse risk factors for healthy aging in Latin America

A pioneering study published today in the journal Nature Aging has unveiled significant heterogeneity in the risk factors affecting healthy aging in Latin America and emphasized the limitations of current models of brain health, which are primarily based on data from high-income countries.

17 Jun 2024

Americans with HIV are living longer. Federal spending isn’t keeping up.

Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. "Diagnosed with HIV 28 years ago, AND TODAY I THRIVE," he wrote in a post in April, which garnered dozens of responses.

17 Jun 2024

St. Jude researchers uncover NLRC5's role in immune response and cell death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

14 Jun 2024

California lawmakers preserve aid to older, disabled immigrants

California lawmakers on Thursday passed a 2024-25 budget that rejected Gov. Gavin Newsom's proposal to cut in-home supportive services for low-income older, blind, and disabled immigrants lacking legal residency.

14 Jun 2024

Younger gut microbiota age reduces cardiovascular disease risk in older adults

Researchers identified gut microbiota signatures and developed a microbial age metric, demonstrating that a younger microbial age may reduce cardiovascular disease (CVD) risk in metabolically unhealthy older adults.

14 Jun 2024

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy (RVCL).

13 Jun 2024

New psychotherapy shows promise in reducing chronic pain for older veterans

A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms.

13 Jun 2024