Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Alzheimer’s patients are less likely to have cataract surgery than those without the condition

People with Alzheimer’s disease are less likely to have cataract surgery than people without Alzheimer’s disease. The procedure rate starts to decrease already one year after the diagnosis, according to a new study from the University of Eastern Finland.

21 May 2021

A better understanding of brain fluid movements can help predict and treat Alzheimer's disease

Scientists don't fully understand what causes Alzheimer's disease, but they have a primary suspect.

20 May 2021

Study could serve as guidepost for developing new therapies for Alzheimer's disease

In a major breakthrough, researchers at Massachusetts General Hospital (MGH) have discovered how amyloid beta--the neurotoxin believed to be at the root of Alzheimer's disease (AD)--forms in axons and related structures that connect neurons in the brain, where it causes the most damage.

20 May 2021

Expert panel provides guidance for optimized design of early drug trials for Alzheimer's, related dementias

An expert panel convened by the Alzheimer's Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) provides guidance on best practices for the design of early drug trials for Alzheimer's disease, frontotemporal degeneration (FTD), and other neurodegenerative dementias.

19 May 2021

Medications commonly prescribed for schizophrenia linked to cognitive impairment

Writing in the May 14, 2021 issue of The American Journal of Psychiatry, a multi-institution team of scientists led by researchers at University of California San Diego School of Medicine report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of worsening cognitive function in patients.

18 May 2021

Abnormal blood levels of proteins linked to dementia, Alzheimer's disease

The development of dementia, often from Alzheimer's disease, late in life is associated with abnormal blood levels of dozens of proteins up to five years earlier, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health

18 May 2021

Researchers use special "micro-grid" recording device to measure hippocampus activity

Researchers at UC San Francisco have observed a new feature of neural activity in the hippocampus - the brain's memory hub - that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.

17 May 2021

Retinal scans may provide an early sign of Alzheimer's disease

While it has been said that the eyes are a window to the soul, a new study shows they could be a means for understanding diseases of the brain.

17 May 2021

Research provides new insight into anesthesia-associated tau spreading in the brain

During the development and progression of Alzheimer's disease, a protein called tau accumulates and spreads in the brain.

12 May 2021

Study examines a pathway responsible for the formation of tau tangles in the brain

Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage.

12 May 2021

Oleoyl-LPE promotes neurite outgrowth and protects against neuronal cell death

Lysophospholipids are phospholipids that have just one fatty acid chain, and in recent years, the role of lysophospholipids in physiology and pathophysiology has attracted attention.

12 May 2021

Patients with neurological symptoms associated with COVID-19 are six times more likely to die

Patients with clinically diagnosed neurological symptoms associated with COVID-19 are six times more likely to die in the hospital than those without the neurological complications, according to an interim analysis from the Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID).

12 May 2021

Spiritual fitness and meditative practice may reduce multiple risk factors for Alzheimer's disease

It is projected that up to 152 million people worldwide will be living with Alzheimer's disease (AD) by 2050. To date there are no drugs that have a substantial positive impact on either the prevention or reversal of cognitive decline.

11 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified.

10 May 2021

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

In the brain of a person with Alzheimer's disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally.

7 May 2021

Defective epithelial barrier responsible for up to two billion chronic diseases

Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface of our skin, lungs and intestine. Defective epithelial barriers have been linked to a rise in almost two billion allergic, autoimmune, neurodegenerative and psychiatric diseases.

6 May 2021

New method shows that tau forms small aggregates as part of the body's normal physiology

It turns out that not all build-ups of tau protein are bad, and a team of researchers from the Perelman School of Medicine at the University of Pennsylvania developed a method to show that.

6 May 2021

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Despite decades of research and investment, the genetic underpinnings of Alzheimer's disease are still largely unknown, stymieing drug development and early diagnosis efforts.

5 May 2021

Alzheimer's Disease News and Research

Further Reading

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

Alzheimer’s patients are less likely to have cataract surgery than those without the condition

A better understanding of brain fluid movements can help predict and treat Alzheimer's disease

Study could serve as guidepost for developing new therapies for Alzheimer's disease

Expert panel provides guidance for optimized design of early drug trials for Alzheimer's, related dementias

Medications commonly prescribed for schizophrenia linked to cognitive impairment

Abnormal blood levels of proteins linked to dementia, Alzheimer's disease

Researchers use special "micro-grid" recording device to measure hippocampus activity

Retinal scans may provide an early sign of Alzheimer's disease

Research provides new insight into anesthesia-associated tau spreading in the brain

Study examines a pathway responsible for the formation of tau tangles in the brain

Oleoyl-LPE promotes neurite outgrowth and protects against neuronal cell death

Patients with neurological symptoms associated with COVID-19 are six times more likely to die

Spiritual fitness and meditative practice may reduce multiple risk factors for Alzheimer's disease

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

Defective epithelial barrier responsible for up to two billion chronic diseases

New method shows that tau forms small aggregates as part of the body's normal physiology

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

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