Oxygen News and Research

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Family of proteins could be effective in reducing damage from ischemic stroke

Boosting a family of naturally occurring proteins that dampens inflammation in the body has been shown to be effective in reducing damage from an ischemic stroke, according to preclinical researchers at The University of Texas Health Science Center at Houston.

1 Sep 2021

Researchers develop new photodynamic therapy for the treatment of deep tumors

Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer.

1 Sep 2021

"FibroCOVID" - An emerging entity

In a recent study, a team of researchers aimed to investigate the prevalence and predictors of fibromyalgia in patients who recovered from COVID-19.

31 Aug 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can become chronic, leading to poor quality of life and potential amputation.

31 Aug 2021

Research highlights the importance of meninges for brain development and pathology

A new study, led by researchers at the University of Gothenburg, have generated the first comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, under normal conditions and after perinatal brain injury.

31 Aug 2021

What might the third wave of COVID-19 in India look like?

A new study applies mathematical modeling to understand what the third wave of the pandemic might look like in India.

29 Aug 2021

$Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction$

Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction

Until now, patients with heart failure with preserved ejection fraction – the most common type of heart failure in the elderly – have had no access to evidenced-based treatments. For the first time, a large clinical trial led by Prof. Dr. Stefan Anker from Charité – Universitätsmedizin Berlin has identified a drug which has a distinctly positive effect on prognosis. In patients affected by this type of heart failure, the drug – empagliflozin – reduces the risk of hospitalization or cardiovascular death by 21 percent. The results of this research have been published in the New England Journal of Medicine.

28 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

Study may pave way for new treatment strategies to limit the progression of solid tumors

Researchers at the University of British Columbia's faculty of medicine and BC Cancer Research Institute have uncovered a weakness in a key enzyme that solid tumour cancer cells rely on to adapt and survive when oxygen levels are low.

28 Aug 2021

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

The U.S. Food and Drug Administration today approved the MicroTransponder Vivistim Paired VNS System (Vivistim System), a first-of-its-kind, drug-free rehabilitation system intended to treat moderate to severe upper extremity motor deficits associated with chronic ischemic stroke—a stroke caused by a blockage of blood flow to the brain with long-lasting symptoms—using vagus nerve stimulation (VNS).

27 Aug 2021

Study: One half of hospitalized COVID-19 patients experience persistent symptoms after one year

Most symptoms of COVID-19 in hospitalized patients are resolved within 12 months, however, around one half still experience at least one persistent symptom, a study of 1,276 patients from Wuhan, China, published in The Lancet, has found.

27 Aug 2021

Review highlights similarities between long COVID and chronic fatigue syndrome

A team of researchers, including two from Johns Hopkins Medicine, have published a review article highlighting similarities between certain lingering symptoms following COVID-19 illness — a condition called "long COVID" — and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating, complex disorder previously known as chronic fatigue syndrome.

26 Aug 2021

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth.

26 Aug 2021

SARS-CoV-2 alpha variant increased COVID-19 severity in Scotland's 3rd wave

A team of UK-based scientists has recently revealed that the alpha variant (B.1.1.7) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the third pandemic wave in Scotland and that the variant is associated with more severe coronavirus disease 2019 (COVID-19). The study is currently available on the medRxiv* preprint server.

25 Aug 2021

Brain refreshing takes place during the dream-active phase of sleep

Scientists have long wondered why almost all animals sleep, despite the disadvantages to survival of being unconscious.

25 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

A new study reports a case of pre-eclampsia complicated by the acute fatty liver of pregnancy (AFLP).

24 Aug 2021

Newly developed CPAP System provides a cost-effective respiratory device for COVID patients

In an attempt to make breathing devices available to low-income areas, scientists have developed the LeVe CPAP System for respiratory support to treat COVID.

24 Aug 2021

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

23 Aug 2021

Oxygen News and Research

Family of proteins could be effective in reducing damage from ischemic stroke

Researchers develop new photodynamic therapy for the treatment of deep tumors

"FibroCOVID" - An emerging entity

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

Research highlights the importance of meninges for brain development and pathology

What might the third wave of COVID-19 in India look like?

Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Study may pave way for new treatment strategies to limit the progression of solid tumors

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

Study: One half of hospitalized COVID-19 patients experience persistent symptoms after one year

Review highlights similarities between long COVID and chronic fatigue syndrome

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

SARS-CoV-2 alpha variant increased COVID-19 severity in Scotland's 3rd wave

Brain refreshing takes place during the dream-active phase of sleep

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

Newly developed CPAP System provides a cost-effective respiratory device for COVID patients

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

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