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Study of immunotherapy for brain cancer metastases shows promising results

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving longer than two years.

2 Jun 2023

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Lupus Therapeutics announced the start of a collaboration to conduct three Phase 3 clinical trials testing an investigational therapeutic ianalumab for systemic lupus erythematosus and lupus nephritis.

2 Jun 2023

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

Researchers at the University of Louisville have received $5.8 million in two grants from the National Institutes of Health to expand their work to better understand and prevent immune system dysregulation responsible for acute respiratory distress, the condition responsible for serious illness and death in some COVID-19 patients.

2 Jun 2023

Study unlocks insights into how 'good fat' tissue could be harnessed to combat obesity, diabetes

New research has unlocked insights into how "good fat" tissue could potentially be harnessed to combat obesity and remove glucose from the blood, helping to control diabetes.

31 May 2023

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

31 May 2023

Important discovery could lead to new treatments for obesity and related diseases

Researchers at the University of East Anglia and the University of Cambridge have made an important discovery in the race to find treatments for obesity and related diseases, such as diabetes.

31 May 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

Alternative gene splicing can impact the risk for alcohol use disorder

Researchers at Indiana University School of Medicine have discovered alternative gene splicing, which occurs during gene expression, can impact a person's risk of alcohol use disorder (AUD).

30 May 2023

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

30 May 2023

Stimulating a bile acid receptor can help protect the vision of premature newborns

It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns.

30 May 2023

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Hydrogen sulfide is usually a highly toxic gas. However, with careful preparation, it can be used to support photothermal therapy (PTT) in treating cancer, as a team of researchers reporting in the journal Angewandte Chemie has recently discovered.

26 May 2023

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

A new study published in the peer-reviewed OMICS: A Journal of Integrative Biology identified genes for virulence and antimicrobial resistance in two bacteria that co-occur with C. difficile, suggesting these pathogens as emerging potential threats in planetary health.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

RECOVER study: An important step toward defining long COVID

A study led by the National Institutes of Health's RECOVER Initiative and supported by NYU Langone Health, home to the effort's Clinical Science Core (CSC), provides an expanded working definition of long COVID.

25 May 2023

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

25 May 2023

New method of analysis flags a precursor to prediabetes

Scientists at Klick Labs have developed a new way to catch the earliest signs the human body is failing to control blood glucose levels, before it reaches prediabetic levels in patients.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Lupus Landmark Study launched to accelerate the development of personalized treatments for lupus patients

The Lupus Research Alliance and its clinical research affiliate Lupus Therapeutics today announced the launch of the Lupus Landmark Study, a groundbreaking observational research study to accelerate the development of personalized treatments for people living with lupus.

24 May 2023

Therapeutics News and Research

Study of immunotherapy for brain cancer metastases shows promising results

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

Study unlocks insights into how 'good fat' tissue could be harnessed to combat obesity, diabetes

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

Important discovery could lead to new treatments for obesity and related diseases

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

Alternative gene splicing can impact the risk for alcohol use disorder

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Stimulating a bile acid receptor can help protect the vision of premature newborns

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Hydrogen sulfide can be used to support photothermal therapy for cancer

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

RECOVER study: An important step toward defining long COVID

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

New method of analysis flags a precursor to prediabetes

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Lupus Landmark Study launched to accelerate the development of personalized treatments for lupus patients

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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