Tumor News and Research

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Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

Study provides novel insights into the molecular mechanisms of melanoma progression

Cong Peng et al., at Department of Dermatology, Xiangya Hospital, Central South University, China, conducted a study titled "NETO2 promotes melanoma progression via activation of the Ca²⁺/CaMKII signaling pathway" that investigates the role of Neuropilin and tolloid-like 2 (NETO2) in melanoma, a deadly form of skin cancer.

2 Aug 2024

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

The U.S. Food and Drug Administration (FDA) has granted accelerated approval for the immunotherapy afamitresgene autoleuecel (Tecelra®, also known as afami-cel) for the treatment of adults with a rare soft tissue cancer called synovial sarcoma.

2 Aug 2024

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University.

2 Aug 2024

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Scientists at St. Jude Children's Research Hospital have created a panel that is able to provide a diagnosis for >90% of pediatric cancer patients by sequencing 0.15% of the human genome.

1 Aug 2024

Applying antifragility theory to cancer could revolutionize treatment methods

Researchers constantly seek innovative approaches to tackle cancer. One concept gaining traction is antifragility, a property where systems not only withstand stress but improve because of it.

1 Aug 2024

New treatment option for endometrial cancer shows promise in phase II trial

The latest trial of a new antibody drug that delivers potent chemotherapy directly to cancer cells for patients with advanced or recurrent endometrial cancer moves ahead to be studied further in a phase III trial.

1 Aug 2024

UC San Diego develops AI tool for rapid, low-cost detection of genomic alterations in cancer

A new generation of artificial intelligence (AI) tools designed to allow rapid, low-cost detection of clinically actionable genomic alterations directly from tumor biopsy slides has been developed by a team led by engineers and medical researchers at University of California San Diego.

1 Aug 2024

Anticancer drugs show promise in reducing Alzheimer's dementia risk

Study finds anticancer drugs, specifically antimetabolites and molecular targeted therapies, may reduce the risk of Alzheimer's type dementia but not vascular dementia.

1 Aug 2024

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them.

31 Jul 2024

Study reveals serotonin's role in ependymoma tumor growth

Do neurons play a role in brain tumor growth and development? Scientists at St. Jude Children's Research Hospital and Baylor College of Medicine have evidence showing that, for childhood ependymomas, they do.

31 Jul 2024

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Researchers at Xiamen University have made a significant advancement in cancer treatment by developing a novel class of X-ray-sensitizers (XSs) that could revolutionize radiotherapy.

31 Jul 2024

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

31 Jul 2024

Study links tissue-resident memory T cells to improved lung cancer outcomes

An extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of tissue-resident memory T cells and how they influence the immune environment of patients with non-small cell lung cancer and their overall prognosis.

30 Jul 2024

Tumor News and Research

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

Study provides novel insights into the molecular mechanisms of melanoma progression

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Applying antifragility theory to cancer could revolutionize treatment methods

New treatment option for endometrial cancer shows promise in phase II trial

UC San Diego develops AI tool for rapid, low-cost detection of genomic alterations in cancer

Anticancer drugs show promise in reducing Alzheimer's dementia risk

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

Study reveals serotonin's role in ependymoma tumor growth

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

Study links tissue-resident memory T cells to improved lung cancer outcomes

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

Fatty acid inhibitor plus chemo could improve treatment efficacy for breast cancer patients with brain metastases

Exploring the role of diet and supplements in cancer prevention

New prognostic marker identified for gastric cancer recurrence risk

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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