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How does intermittent fasting affect β cell function and diabetes risk

Research shows short-term fasting improves glucose regulation, while long-term fasting in young mice impairs β cell function, potentially increasing T1D risk.

18 Feb 2025

Cancer-free for 18 years: CAR-T therapy sets new milestone in neuroblastoma treatment

A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children with neuroblastoma, with one patient remaining cancer-free for over 18 years.

17 Feb 2025

Internal body clock influences eating habits of obese teens

Researchers found that teens with obesity ate more later in the day than their peers of healthy weight, and that their eating behaviors were strongly influenced by their internal body clock.

17 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Children with ARFID at higher risk for long-term health conditions

Children with avoidant restrictive food intake disorder (ARFID) have an elevated risk of developing psychiatric and physical conditions, a new study from Karolinska Institutet published in JAMA Pediatrics reports.

17 Feb 2025

UChicago researchers develop hydrogel from malva nut for medical use

A nut used in herbal tea has become a hydrogel perfect for a variety of biomedical uses in new research from the University of Chicago Pritzker School of Engineering (UChicago PME) and UChicago Chemistry Department.

17 Feb 2025

New gene switch may lead to precise treatments for metabolic diseases

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025

Study reveals key role of opsin 3 in regulating food intake and energy balance

Scientists discovered years ago that the hypothalamus - which helps to manage body temperature, hunger, sex drive, sleep and more - includes neurons that express the protein opsin 3 (OPN3).

14 Feb 2025

Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.

14 Feb 2025

Brain's opiate pathway triggers dessert cravings even after fullness

Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers from the Max Planck Institute for Metabolism Research in Cologne have now discovered that what we call the "dessert stomach" is rooted in the brain.

14 Feb 2025

Intermittent fasting may harm insulin-producing cells in teens

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

14 Feb 2025

Expert articles offer insight on tackling the UK’s cardiovascular health crisis

A new collection of articles offering expert insight and policy recommendations to tackle the national cardiovascular health crisis has just been released.

14 Feb 2025

Infants with cystic fibrosis show stunted gut microbiome development

Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health.

14 Feb 2025

Evidence increasingly links ultra-processed food consumption to weight gain

Research shows that promoting fruits and vegetables isn't enough to combat weight gain, highlighting the significant role of ultra-processed foods in obesity.

14 Feb 2025

IgG-guided diet outperforms sham diet in clinical trial

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

13 Feb 2025

Rethinking red meat: Are dietary guidelines missing the bigger picture?

Research highlights the critical role of red meat in providing essential nutrients like iron, zinc, and B12, particularly for vulnerable populations, while questioning the low-certainty evidence linking it to chronic diseases. It urges policymakers to balance health, environmental, and economic factors when considering dietary guidelines.

13 Feb 2025

Online weight management program helps rural residents lose weight

People living in rural areas are at greater risk for obesity than the general population, and they often have limited access to healthy, affordable food, physical activity facilities, public transportation, and health care institutions.

13 Feb 2025

Could yogurt help prevent certain colorectal cancers? New study explores the link

Regular yogurt intake may lower the risk of Bifidobacterium-positive colorectal cancer, particularly in the proximal colon, but does not reduce the risk of Bifidobacterium-negative tumors. Further research is needed to confirm these findings and understand yogurt’s role in gut health and cancer prevention.

13 Feb 2025