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Women taking oral estrogen therapy more likely to develop high blood pressure

Women ages 45 years and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal (topical, applied to the skin) or vaginal formulations, according to new research published today in Hypertension, a peer-reviewed American Heart Association journal.

5 Jun 2023

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Researchers described severe and fatal infections in neonates caused by a new echovirus 11 (E-11) variant in France.

5 Jun 2023

Cutting free flu jabs for 50-64-year-olds and mpox vaccines could lead to future strains on the NHS, says expert

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5 Jun 2023

Study of immunotherapy for brain cancer metastases shows promising results

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving longer than two years.

2 Jun 2023

Lymphoid depletion associated with suppressed APC function characterizes the lethality of COVID-19 in mice

Individuals who are immunocompromised are considered at higher risk for severe or longer disease with COVID-19. Understanding the systemic immune response is vital for research efforts to reduce its effects on multiple organs.

2 Jun 2023

Long-term side effects of modern treatment for rheumatoid arthritis

Janus kinase inhibitors (JAKi) and biologics are the cornerstone of modern treatment for rheumatoid arthritis (RA). But there have been concerns over long-term side effects.

1 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year.

31 May 2023

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

First-in-human clinical trial of liver dialysis device successfully completed

The first successful in-patient trial of liver dialysis* has been completed by researchers from UCL, the Royal Free Hospital, UCL spin-out Yaqrit and their collaborators.

31 May 2023

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers from Japan fed isocaloric diets with varying amounts of protein to young and middle-aged male mice.

31 May 2023

CSEM collaborates with innovative Swiss start-up MOMM diagnostics to introduce revolutionary preeclampsia test

CSEM’s Tools for Life Sciences team is partnering with MOMM Diagnostics to develop a cutting-edge point-of-care solution for preeclampsia diagnostics. This ground-breaking multiplexed sensing device simultaneously detects two crucial biomarkers associated with this prevalent disease.

From CSEM 31 May 2023

Red alert on energy drinks: Severe health risks for kids and teens

Research investigates the adverse health effects associated with energy drink consumption in children and adolescents. The study highlights the impact on different organ systems, the role of trigger factors, and the presence of preexisting health conditions.

30 May 2023

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

The low blood oxygen levels of obstructive sleep apnea cause widespread changes in gene activity throughout the day, according to a new study in the open-access journal PLOS Biology by David Smith of Cincinnati Children's Hospital Medical Center, US, and colleagues.

30 May 2023

Using ex vivo gene therapy to fight obesity and diabetes in mice

A scientific team from the University of Barcelona and the CIBERobn has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease.

30 May 2023

Risk of long COVID in the United Kingdom and Hong Kong cohorts

Study evaluates the risk of post-acute sequelae of COVID-19 in the United Kingdom (UK) and Hong Kong (HK).

30 May 2023

Stimulating a bile acid receptor can help protect the vision of premature newborns

It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns.

30 May 2023

Precision nutrition vs. low-fat diet: No significant difference in diabetes management

Researchers compare changes in hemoglobin A1c and glycemic variability to understand the impacts of two calorie-restricted weight loss diets.

30 May 2023

Obesity-related cancers take a toll in Southern Africa: Study reveals alarming trends

Research analyzes the prevalence and mortality rates of obesity-related cancers in 16 Southern African countries. It identifies leukemia, esophageal cancer, and colon/rectum cancer as leading causes of cancer mortality in males, and breast cancer, leukemia, and esophageal cancer in females.

29 May 2023

Passing on Polycystic Ovary Syndrome: Health risks for Male offspring of Women with PCOS

In this interview, we spoke to two researchers from the Karolinska Institutet about their latest work that investigated how PCOS can affect the health of future generations of men.

29 May 2023

Liver News and Research

Women taking oral estrogen therapy more likely to develop high blood pressure

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Cutting free flu jabs for 50-64-year-olds and mpox vaccines could lead to future strains on the NHS, says expert

Study of immunotherapy for brain cancer metastases shows promising results

Lymphoid depletion associated with suppressed APC function characterizes the lethality of COVID-19 in mice

Long-term side effects of modern treatment for rheumatoid arthritis

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

First-in-human clinical trial of liver dialysis device successfully completed

Moderate-protein diet improves metabolic health in both young and middle-aged mice

CSEM collaborates with innovative Swiss start-up MOMM diagnostics to introduce revolutionary preeclampsia test

Red alert on energy drinks: Severe health risks for kids and teens

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

Using ex vivo gene therapy to fight obesity and diabetes in mice

Risk of long COVID in the United Kingdom and Hong Kong cohorts

Stimulating a bile acid receptor can help protect the vision of premature newborns

Precision nutrition vs. low-fat diet: No significant difference in diabetes management

Obesity-related cancers take a toll in Southern Africa: Study reveals alarming trends

Passing on Polycystic Ovary Syndrome: Health risks for Male offspring of Women with PCOS

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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