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Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

ASH releases updated recommendations for severe acquired aplastic anemia care

The American Society of Hematology (ASH) released guidelines on the diagnosis and management of severe acquired aplastic anemia, a rare and life-threatening bone marrow failure disorder.

1 Apr 2026

Study reveals molecular control of tooth root formation and growth

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to control signaling and differentiation in dental progenitor cells.

1 Apr 2026

How vitamin D in the first 1,000 days may shape lifelong health

This narrative review argues that vitamin D is clearly important for skeletal health during the first 1,000 days of life and may also shape immune, metabolic, and selected neurodevelopmental pathways during early development. However, the authors stress that human evidence for most non-skeletal outcomes remains heterogeneous, with benefits appearing most consistent in populations with baseline deficiency.

31 Mar 2026

Machine learning helps predict risks during stem cell therapy for myeloma

Multiple myeloma is a cancer in which plasma cells, which normally produce antibodies, multiply uncontrollably in the bone marrow.

31 Mar 2026

Restoring tissue stiffness may reduce inflammation in gum disease

Periodontitis is a serious chronic inflammatory form of gum disease that affects millions worldwide. It can lead to tooth loss and the destruction of supporting bone.

31 Mar 2026

Uncovering the hidden retinal risks of modern dentistry

Dentists are exposed to intense lighting for long hours, but its long-term impact on eye health is often overlooked. This study evaluates whether chronic exposure to dental lighting, especially blue and white LEDs, can damage the retina and disrupt its normal function. By combining human data with advanced imaging and animal models, the research uncovers hidden occupational risks and highlights the need for safer lighting practices to help protect dentists' vision.

31 Mar 2026

Collaboration advances EMA601 as potential first-in-class stroke therapy

Boehringer Ingelheim and the Lower Franconian biotech company EMFRET Analytics have signed a cooperation and license agreement for the preclinical development program of the GPVI‑blocking antibody EMA601.

30 Mar 2026

$Heart health linked to higher fracture risk in postmenopausal women$

Heart health linked to higher fracture risk in postmenopausal women

Postmenopausal women face a high risk of bone fractures. Due to declines in estrogen levels, which can lead to an increased risk of osteoporosis, even a low-impact fall can result in a serious hip, back or wrist injury.

27 Mar 2026

FDA approves first gene therapy for rare pediatric immune disorder

Dr. Donald Kohn has been developing gene therapies for rare pediatric immune disorders for over 30 years.

27 Mar 2026

Estradiol patches as effective as injections for locally advanced prostate cancer

Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers.

25 Mar 2026

Study finds AI-generated X-rays can fool radiologists and chatbots

Researchers found that both radiologists and multimodal AI models had only moderate success distinguishing synthetic radiographs from real clinical images, even when told fakes were present. The study warns that increasingly realistic AI-generated X-rays could be misused in medicine, research, insurance, and litigation, strengthening the case for watermarking, clinician training, and dedicated detection tools.

25 Mar 2026

Breakthrough research reshapes understanding of T cell immune responses

In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S P Hicks Endowed Professor of Pathology, and Marcin Cieslik, assistant professor of pathology, both from University of Michigan Rogel Cancer Center, discovered a novel way the immune system, specifically T-cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immunology and bone marrow transplantation.

24 Mar 2026

Deepfake X-rays can deceive radiologists and AI systems

Neither radiologists nor multimodal large language models (LLMs) are able to easily distinguish artificial intelligence (AI)-generated "deepfake" X-ray images from authentic ones, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

24 Mar 2026

Study reveals genetic impact of Agent Orange on bone marrow cancers

More than 50 years after Agent Orange was used in Vietnam, a new national study published online ahead of print in Blood Advances highlights the genetic changes that link exposure to Agent Orange to myelodysplastic syndromes (MDS), a group of bone marrow cancers that can progress to acute leukemia.

23 Mar 2026

Study revises the understanding of neutrophil dynamics during respiratory viral infection

Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells has been a subject of debate.

23 Mar 2026

Snus linked to gum damage but tooth decay risk unclear

Snus is clearly linked to damage to the gums. The connection to tooth decay, however, remains unclear, according to a systematic review. When it comes to white snus, more studies are needed.

23 Mar 2026

Scientists turn red blood cells into long-lasting drug and imaging carriers in mice

A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting carriers for imaging agents and therapies, opening a new route for safer drug delivery and vascular imaging.

23 Mar 2026

New method uses biomarkers to determine a person's biological age

Aging is a highly individual process. An international consortium coordinated by researchers in Konstanz has developed a method that uses biomarkers to determine a person's biological age - a valuable tool for research on ageing and the development of new approaches in preventive medicine.

19 Mar 2026

Study finds GLP-1 medicines cut fat while preserving muscle function

Researchers found that GLP-1 medicines caused weight loss mainly through fat reduction, with only modest decreases in absolute muscle mass and no disproportionate loss of muscle function. In mice, physical performance improved, while in a small 12-week human pilot trial, strength was preserved despite reduced thigh muscle size.

18 Mar 2026