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Neuronal gene malfunction is behind seizures associated with long QT syndrome, study suggests

Most people with a medical condition called long QT syndrome have a mutation in a gene that causes bouts of fast, chaotic heartbeats.

9 Aug 2019

Hinge-like protein may unlock new pathways for cystic fibrosis treatment

In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is mutated in people with the disease.

10 Jul 2019

Nanion launches HTS automated patch clamp platform

The SyncroPatch 384i is a giga-ohm seal HTS automated patch clamp platform designed for flexibility, ease-of-use and reliability.

From Nanion Technologies 25 Jun 2019

E-cigarette vaping with nicotine appears to impair mucus clearance

E-cigarette vaping with nicotine appears to hamper mucus clearance from the airways, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

7 Jun 2019

Neurons rely on their own electrical signals to keep track of normal functions

Nerve cells, or neurons -- specifically the "workhorse cells" involved in walking, breathing and chewing -- can adjust to changes in the body, but they never stop working unless there is an fatal injury.

10 May 2019

Discovery about cold sensing could pave way for new pain relief drugs

Researchers at UCL have shown for the first time that mammals detect different intensities of cold using distinct sensory neuron systems, a finding which could lead to the development of new drugs to treat cold pain.

24 Apr 2019

Researchers annotate key neuronal proteins in lamprey genome

The lamprey, an eel-like primitive vertebrate, is a popular organism for neurobiology studies because it has a relatively simple nervous system.

16 Apr 2019

Metrion Biosciences announces closure of funding round

Metrion Biosciences Ltd, the specialist ion channel contract research and drug discovery company, announced today that it has completed a fully subscribed funding round on 14 March.

From Metrion Biosciences Limited 2 Apr 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic-scale drug-cardiac cells interactions.

8 Feb 2019

Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

Metrion Biosciences and LifeArc have entered into a collaboration agreement for an ion channel drug discovery project in the field of neuroscience.

From Metrion Biosciences Limited 30 Jan 2019

How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

Investigational topical cream may be effective for treating atopic dermatitis

A study published in the British Journal of Dermatology indicates that an investigational nonsteroidal topical cream may be effective for treating atopic dermatitis, one of the most common inflammatory skin diseases.

9 Jan 2019

Researchers report novel findings on plant hormone

Jasmonic acid is not just the aromatic odor of the plant Jasminum grandiflorum used in cosmetics and perfume industries. Plants wounded by e.g. chewing herbivores produce jasmonic acid as a defense signal, as a phytohormone to mount their defense responses - this includes for example the formation of toxic substances.

10 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

Scientists identify new drug target for potential blood pressure treatment

Scientists have identified a key player in blood pressure regulation and have shown that switching it off reduces blood pressure in mice, according to new research in eLife.

6 Dec 2018

Aurora Biomed organizes 2018 Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the "2018 Shunde Biomedical Industry Investment Promotion Conference" which ran in parallel with the Precision Medicine and Ion Channel Retreat was successfully held at the Ramada Plaza Hotel, Shunde, Guang Dong, China.

3 Dec 2018

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40% (1 billion) of adults aged 25 and above have been diagnosed with hypertension. A positive correlation between salt intake and blood pressure has long been postulated.

30 Nov 2018

Insights from the Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the 2018 Shunde Biomedical Industry Investment Promotion Conference was successfully held at the Ramada Plaza Hotel, Shunde, GuangDong, China

From Aurora Biomed Inc. 29 Nov 2018