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Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

A review of the risk factors associated with cancer evolution

Researchers reviewed existing data on tumor-promotive risk factors and their underlying mechanisms.

17 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Mediterranean diet and the modulation of mitochondrial function

Researchers reviewed the current knowledge related to the Mediterranean diet (MedDiet) and the role of mitochondria concerning health outcomes.

7 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

How nanomedicine is revolutionizing care for cardiovascular disease

Researchers review recent advancements in nanomedicine treatment options for cardiovascular disease.

6 Apr 2023

Novel combination treatment for head and neck cancers leads to antitumor effects

Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) and lung cancer can have disruptive mutations in TP53and/or CDKN2A tumor suppressor genes, which are associated with poor patient survival.

5 Apr 2023

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

In a new study published in The FASEB Journal, investigators demonstrated the potential of a molecule that may help overcome some of the devastating symptoms of Duchenne muscular dystrophy (DMD), the most common life-limiting congenital neuromuscular disorder.

5 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Researchers examined the significance of dietary lipids in the gut-brain axis of individuals with T2DM.

4 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Kinase News and Research

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A review of the risk factors associated with cancer evolution

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Mediterranean diet and the modulation of mitochondrial function

Pathophysiology, comorbidities, and interventions related to childhood obesity

How nanomedicine is revolutionizing care for cardiovascular disease

Novel combination treatment for head and neck cancers leads to antitumor effects

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Capsaicin and its health benefits

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Metformin may reduce the risk of osteoarthritis

How does diet affect inflammation?

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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