Metformin News and Research

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Metformin is the active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body’s use of the glucose. Metformin is a type of antidiabetic agent.

High-dose drug for erectile dysfunction improves long-term blood sugar levels in diabetes patients

A small group of patients with type 2 diabetes significantly improved their long-term blood sugar levels when treated with high-dose tadalafil, a medication used to treat erectile dysfunction.

5 May 2023

Researchers identify a druggable copper-signaling pathway that drives inflammation

Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues.

27 Apr 2023

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well.

24 Apr 2023

Diabetes drug may help recover from short periods of severe food insecurity or anorexia

New research results suggest that the widely used diabetes drug metformin may be beneficial for recovering from short periods of severe food insecurity or anorexia.

21 Apr 2023

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Sugary beverages were associated with a higher risk of dementia, whereas moderate intake of natural juices was associated with a lower dementia risk.

17 Apr 2023

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

In an article published in the journal Current Opinion in Microbiology, scientists have provided a detailed overview of the factors affecting maternal gut microbiota during pregnancy and its impact on maternal and infant health.

17 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

Metformin may reduce the risk of osteoarthritis

In a recent study published in JAMA Network Open, researchers in the United States (US) determined the risk of osteoarthritis (OA) and joint replacement among adults with type 2 diabetes (T2D) following metformin or sulfonylurea treatment.

27 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Early outpatient treatment of COVID-19 with metformin could reduce the risk of developing long COVID

In a recent study posted to Preprints with The Lancet*, a team of researchers from the United States investigated whether early outpatient treatment of coronavirus disease 2019 (COVID-19) patients with fluvoxamine, ivermectin, or metformin could prevent long coronavirus disease (long COVID).

9 Mar 2023

Maternal obesity alters the structure of placenta more than gestational diabetes mellitus

Maternal obesity alters the structure of the placenta (a vital organ that nourishes the baby during pregnancy) more than gestational diabetes mellitus (GDM; a condition is diagnosed by poor glucose control in pregnancy).

28 Feb 2023

Study may elucidate metformin's potential role in longevity through DNA methylation

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

22 Feb 2023

Challenges associated with prescribing exercise to diabetic patients taking metformin

In a recent study published in the Sports Medicine and Health Science journal, researchers assessed the impact of exercise precision medicine on type 2 diabetes.

21 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Preventing, diagnosing, and treating cardiovascular disease in women

An article published in the journal Medical Clinics of North America provides recent updates on cardiovascular disease prevention, diagnosis, and treatment in women.

8 Feb 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Metformin News and Research

Further Reading

High-dose drug for erectile dysfunction improves long-term blood sugar levels in diabetes patients

Researchers identify a druggable copper-signaling pathway that drives inflammation

Researchers discover a key player in preventing 'insulin shock'

Diabetes drug may help recover from short periods of severe food insecurity or anorexia

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

Pathophysiology, comorbidities, and interventions related to childhood obesity

Metformin may reduce the risk of osteoarthritis

Childhood and adolescent obesity: time to act

Early outpatient treatment of COVID-19 with metformin could reduce the risk of developing long COVID

Maternal obesity alters the structure of placenta more than gestational diabetes mellitus

Study may elucidate metformin's potential role in longevity through DNA methylation

Challenges associated with prescribing exercise to diabetic patients taking metformin

Are SGLT2 inhibitors the next blockbuster drug?

Preventing, diagnosing, and treating cardiovascular disease in women

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Review shows metformin usage to be associated with better COVID-19 outcomes

Can diets reverse or delay aging?

New research extensively explores 12 distinctive aging traits

Metformin use associated with lower risk of joint replacement in people with type 2 diabetes

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