RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Age-associated B cells found to be important drivers of lupus

A group of University of Pittsburgh researchers has given new meaning to "knowing your ABCs."

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and an increased risk of blood cancers.

2 Mar 2023

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer — altering cancer cells so that they teach the body's immune system to fight the very cancer the cells came from.

2 Mar 2023

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.

2 Mar 2023

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

Researchers analyzed polygenic risk scores in whole genome sequences obtained from blood samples of long COVID patients to determine genomic predictors of long COVID.

2 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

In a recent study published in the journal Vaccines, researchers in Saudi Arabia and the United States examined immune responses and immunoglobulin G (IgG) cross-reactivity in individuals infected with Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Feb 2023

New purification approach could help make protein drugs more affordable and accessible

One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it.

28 Feb 2023

New solutions to boost Africa’s vaccine production

The COVID-19 pandemic has highlighted the importance of vaccines in controlling infectious disease in sub-Saharan Africa and renewed interest in vaccine research and development across the continent.

28 Feb 2023

Using the origami technique to design RNA nanostructures

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

A review of respiratory viruses monitored in wastewater samples

Researchers review previous studies discussing the content or respiratory viruses in wastewater samples.

28 Feb 2023

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Researchers investigate whether transmissible SARS-CoV-2 variants developed during infection by culturing and sequencing strains obtained from serial oral and nasal samples of community-residing COVID-19 patients.

28 Feb 2023

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

New insights into how amino acids shaped the genetic code of ancient microorganisms

By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today - including plants, animals, and humans.

27 Feb 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis - the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease - involve the buildup of a protein called TDP-43.

27 Feb 2023

Innovative methodology to detect viral RNA

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia, the Institute of Microelectronics of Barcelona and the Aragon Nanoscience and Materials Institute of Aragon —a joint institute of the CSIC and the University of Zaragoza— have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

27 Feb 2023

RNA News and Research

Further Reading

Age-associated B cells found to be important drivers of lupus

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Reprogrammed tumor cells could teach the body's immune system to fight cancer

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

What is the role of B cells in breast cancer pathology?

Key 'traffic light' mechanism controlling genetic activity within cells revealed

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

New purification approach could help make protein drugs more affordable and accessible

New solutions to boost Africa’s vaccine production

Using the origami technique to design RNA nanostructures

A review of respiratory viruses monitored in wastewater samples

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

New insights into how amino acids shaped the genetic code of ancient microorganisms

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Innovative methodology to detect viral RNA

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo