Alzheimer's Disease News and Research

RSS

Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New "machine learning" method helps analyze large amounts of biological data

Studying genetic material on a cellular level, such as single-cell RNA-sequencing, can provide scientists with a detailed, high-resolution view of biological processes at work.

26 Mar 2021

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

A University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.

25 Mar 2021

Study shows persisting cognitive benefits of common Alzheimer’s treatment

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects.

25 Mar 2021

Researchers are testing wearable devices to detect early Alzheimer's, other neurodegenerative diseases

The development of a wearable to detect early Alzheimer's and other neurodegenerative diseases years before symptoms show has taken a step closer to reality today, as UK charity Alzheimer's Research UK announces a partnership with Boston University that will see the first digital data flowing into its global Early Detection of Neurodegenerative diseases (EDoN) initiative.

25 Mar 2021

Alzheimer’s symptoms linked to COVID-induced brain injury

New research shows further evidence between COVID-19 infection and the development of long-term neurological symptoms. The findings found COVID-induced neuroinflammation and microvascular injury contributed to dementia-like symptoms. However, they also found evidence indicating a low possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly invading the brain.

24 Mar 2021

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Being persistently lonely during midlife (ages 45-64) appears to make people more likely to develop dementia and Alzheimer's Disease (AD) later in life. However, people who recover from loneliness, appear to be less likely to suffer from dementia, compared to people who have never felt lonely.

24 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Previous research identified the interferon-responsive OAS1 gene as a risk gene for Alzheimer's disease. OAS1 is an enzyme that binds to double-stranded RNA and induces the conformation to create oligoadenylates. They also activate RNase L to break down RNA.

23 Mar 2021

‘Zombie’ cells come to life after the death of the brain

In the hours after we die, certain cells in the human brain are still active. Some cells even increase their activity and grow to gargantuan proportions, according to new research from the University of Illinois Chicago.

23 Mar 2021

Exercise increases blood flow to the brain, study shows

It's not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well. A new study by researchers at UT Southwestern shows that when older adults with mild memory loss followed an exercise program for a year, the blood flow to their brains increased.

23 Mar 2021

Socioeconomic deprivation linked to large proportion of dementia deaths in England, Wales

A large proportion of dementia deaths in England and Wales may be due to socioeconomic deprivation, according to new research led by Queen Mary University of London.

23 Mar 2021

Widening ideological gap in the U.S. may contribute to challenges in medical research

The lightning speed with which scientists developed and tested the COVID-19 vaccine is a true scientific triumph -- one that would not have been possible without the more than 70,000 volunteers who participated in clinical trials of the vaccine.

23 Mar 2021

Researchers test novel gene regulation approach to treat brain diseases

Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies.

22 Mar 2021

Consumption of processed meat associated with increased risk of dementia

Scientists from the University of Leeds's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease.

21 Mar 2021

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers have used a genetic engineering strategy to dramatically reduce levels of tau--a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer's disease--in an animal model of the condition.

21 Mar 2021

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

Have you forgotten where you laid your keys? Ever wondered where you had parked your car? Or having trouble remembering the name of the new neighbor? Unfortunately, these things seem to get worse as one gets older.

19 Mar 2021

New high-throughput system for testing drug candidates to treat brain diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

18 Mar 2021

New Alzheimer's model may help test novel treatments

Our knowledge of Alzheimer's disease has grown rapidly in the past few decades but it has proven difficult to translate fundamental discoveries about the disease into new treatments.

18 Mar 2021

UTSW researchers identify the structure of a key cell-surface protein

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes.

17 Mar 2021

Researchers find a better way to identify cells and understand the mechanisms of diseases

In researching the causes and potential treatments for degenerative conditions such as Alzheimer's or Parkinson's disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behavior changes such as declining memory or impaired balance and tremors.

17 Mar 2021

Alzheimer's Disease News and Research

Further Reading

New "machine learning" method helps analyze large amounts of biological data

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

Study shows persisting cognitive benefits of common Alzheimer’s treatment

Researchers are testing wearable devices to detect early Alzheimer's, other neurodegenerative diseases

Alzheimer’s symptoms linked to COVID-induced brain injury

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

‘Zombie’ cells come to life after the death of the brain

Exercise increases blood flow to the brain, study shows

Socioeconomic deprivation linked to large proportion of dementia deaths in England, Wales

Widening ideological gap in the U.S. may contribute to challenges in medical research

Researchers test novel gene regulation approach to treat brain diseases

Consumption of processed meat associated with increased risk of dementia

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

New high-throughput system for testing drug candidates to treat brain diseases

New Alzheimer's model may help test novel treatments

UTSW researchers identify the structure of a key cell-surface protein

Researchers find a better way to identify cells and understand the mechanisms of diseases

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News