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Yale-led team creates new resource that is an important step toward personalized care

Each person has about 4 million sequence differences in their genome relative to the reference human genome.

3 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

The association between regular glucosamine use and risk of dementia

Researchers assessed the association between daily glucosamine consumption and the risk of new-onset dementia.

3 Apr 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

Study shows a genetic association of diarrhea in children

Susceptibility to diarrhea, a major cause of infant deaths in low- and middle-income countries, has genetic links which could hold the key to new treatments, research suggests.

31 Mar 2023

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

scientists investigate the neurocognitive correlates of genetic vulnerability to major depressive disorder and Alzheimer's disease.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

New research may upend long-held scientific dogma about short telomeres and cancer risk

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

30 Mar 2023

Scientists uncover how some skin cancers resist treatment at the end of life

Scientists have found out how some skin cancers stop responding to treatment at the end of life.

30 Mar 2023

A novel species of dependoparvovirus has been identified in monk parakeets in Madrid

A novel dependoparvovirus identified from 28 healthy monk parakeets from urban regions of Spain.

30 Mar 2023

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Researchers evaluated the effects of poor diet quality and lifestyle behaviors on modifying the genomic susceptibility to impulsivity.

30 Mar 2023

Which functional and structural changes in the brain are associated with blood pressure elevation and cognitive impairment in humans?

Researchers identified brain structures related to cognitive impairment associated with elevated blood pressure (BP).

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

Using explainable AI framework for gut microbiome-based colorectal cancer classification

The gut microbiome comprises a complex population of different bacterial species that are essential to human health.

29 Mar 2023

A novel approach for analyzing foodborne zoonotic E. coli

Researchers in the US identified extraintestinal Escherichia coli infections using source-related mobile genetic elements.

29 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view.

27 Mar 2023

Beethoven's cause of death revealed through DNA analysis of his hair

In a recent article published in the journal Current Biology, an international team of researchers sequenced the whole genome to high coverage from eight authenticated hair strands from Ludwig van Beethoven, one of the most influential European classical music composers born in 1770. He died on March 27, 1827.

27 Mar 2023

Genome News and Research

Yale-led team creates new resource that is an important step toward personalized care

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

The association between regular glucosamine use and risk of dementia

Transposable elements in various cancers could be used to harness novel immunotherapies

Study shows a genetic association of diarrhea in children

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

New research may upend long-held scientific dogma about short telomeres and cancer risk

Scientists uncover how some skin cancers resist treatment at the end of life

A novel species of dependoparvovirus has been identified in monk parakeets in Madrid

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Which functional and structural changes in the brain are associated with blood pressure elevation and cognitive impairment in humans?

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Using explainable AI framework for gut microbiome-based colorectal cancer classification

A novel approach for analyzing foodborne zoonotic E. coli

COVID-19 activates endogenous retroviruses within our genome

Two distinct subtypes of insulin-producing beta cells identified

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Beethoven's cause of death revealed through DNA analysis of his hair

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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