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Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

In this study, the authors have specifically studied the interactions of epithelial cells, a subset of cytokines and macrophages.

10 May 2022

seqWell’s plexWell technology selected by California Conservation Genomics Project for conservation genomics research

seqWell, a global provider of next-generation sequencing library technologies based on its proprietary plexWell™ multiplexing platform, today announced a partnership with California Conservation Genomics Project.

10 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Researchers developed a novel protocol to examine dopamine (DA) neurons extracted from Parkinson’s disease (PD) patients using single-cell genomic sequencing.

9 May 2022

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

In a recently published ‘Letter to the Editor’ in the journal Microbiology Spectrum, scientists have described the procedure of polymerase chain reaction (PCR)-based genotyping in identifying delta-omicron coinfection in clinical samples.

9 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

Researchers at Children's Hospital of Philadelphia have developed a new tool to help researchers interpret the clinical significance of somatic mutations in cancer.

6 May 2022

Inversions in the human genome found to be more common than previously thought

Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.

6 May 2022

miRNAs associated with varying clinical presentations of SARS-CoV-2

A recent article published in the journal iSCIENCE demonstrated different micro ribonucleic acids (miRNAs) linked with various presentations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

5 May 2022

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

New method improves polygenic prediction of disease risk across diverse populations

Polygenic risk scores (PRS) are promising tools for predicting disease risk, but current versions have built-in bias that can affect their accuracy in some populations and result in health disparities.

5 May 2022

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

5 May 2022

Genomic News and Research

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

seqWell’s plexWell technology selected by California Conservation Genomics Project for conservation genomics research

T cell behavior informs metastatic melanoma outcomes

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

Inversions in the human genome found to be more common than previously thought

miRNAs associated with varying clinical presentations of SARS-CoV-2

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

New method improves polygenic prediction of disease risk across diverse populations

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

Scientists investigate the association between walking pace and leucocyte telomere length

Study identifies two new Omicron lineages associated with a resurgence in infections in South Africa

Genetic risk score has potential to improve prevention of severe knee and hip osteoarthritis

The war against COVID-19: reinfection, vaccines, and herd immunity

Study offers a path to closing the knowledge gap about differences in breast cancer genes

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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