Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

The role of neuron and dopamine loss in Parkinson's Disease (PD) has long been recognized by neuroscientists.

19 Oct 2021

Immune system activation is modulated according to the time of day

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

18 Oct 2021

Researchers use game theory to understand how cells compete in tumors

Game theory applied to cell encounters inside a tumor provides a sociological perspective on the possible behaviors of cells in a collectivity, and offers a more comprehensive understanding of the complex rules that govern a neoplasm.

18 Oct 2021

Researchers illustrate the importance and value of sharing negative research results

In the era of "publish or perish," research results that disprove the hypothesis tested often go unpublished. In addition, many researchers who have been unable to reproduce results from other laboratories have found it difficult to publish their findings.

18 Oct 2021

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease 2019 (COVID-19).

17 Oct 2021

Personality traits associated with hallmarks of Alzheimer’s disease

New research from the Florida State University College of Medicine found that changes in the brain associated with Alzheimer's disease are often visible early on in individuals with personality traits associated with the condition.

12 Oct 2021

NYU Langone launches new center to advance scientific discovery and treatment of neurodegenerative diseases

NYU Langone Health announced today the launch of the Parekh Center for Interdisciplinary Neurology, made possible by a gift provided by Deven and Monika Parekh through the Psquared Charitable Foundation.

11 Oct 2021

CDC and ClinGen partner to develop expert curated variant list for the genomic community

The Centers for Disease Control and Prevention's Genetic Testing Reference Material Program (GeT-RM) has partnered with the Clinical Genome Resource (ClinGen) to develop a publicly available list of 546 expert curated pathogenic variants in 84 genes for use in next-generation sequencing (NGS) genetic testing.

11 Oct 2021

Study investigates the link between gray matter and white matter neurodegeneration in subjective cognitive decline

Aging-US published "The interplay between gray matter and white matter neurodegeneration in subjective cognitive decline" which reported that subjective cognitive complaints were assessed through 9 questions covering amnestic and non-amnestic cognitive domains. In these authors' cohorts, 123 individuals endorsed from one to six subjective cognitive complaints, while 102 individuals reported zero complaints.

11 Oct 2021

Prior immunity to influenza, not SARS-CoV-2, prevents severe disease and mortality

Researchers from the Israel Institute of Biological Research delineated the interplay between IAV and SARS CoV-2 infections.

11 Oct 2021

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

The National Institutes of Health has awarded grants to researchers in the Perelman School of Medicine at the University of Pennsylvania to support "highly innovative and broadly impactful" biomedical science through the NIH Common Fund's High-Risk, High-Reward Research program. The seven awards total approximately $8.2 million over five years,

8 Oct 2021

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer's disease pathology.

8 Oct 2021

NIH grant to benefit researcher's effort in developing a new method for detecting breast cancer

Electrical engineering professor Magda El-Shenawee's effort to develop a more accurate and less-invasive method for detecting breast cancer will benefit from a $424,545 grant from the National Institutes of Health.

8 Oct 2021

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

A new preprint shows the potential role of a host protease cathepsin L inhibitor, which mediates viral entry into the host cell by its effect on the viral spike protein.

8 Oct 2021

High fat diet exacerbates Alzheimer's disease in mouse model

Research has shown that individuals who have diabetes are more prone to develop dementia. Although people are widely aware of diabetes, owing to its common occurrence, they are less aware of prediabetes. Similar to diabetes, prediabetes is also associated with impaired glucose tolerance. However, unlike diabetes, patients with prediabetes show a slight increase in insulin and fasting blood glucose rather than hyperglycemia.

7 Oct 2021

University of Washington partners with USAID to better identify and prevent future pandemics

Randy CarnellLaboratory medicine scientists look through the window of equipment used in analyzing virus samples.

6 Oct 2021

Novel technique enables 3D visualization of cells containing melanin pigment

To understand the biological underpinnings of skin and hair pigmentation and related diseases such as albinism or melanoma, scientists and doctors need quantitative, three-dimensional information about the architecture, content and location of pigment cells. Penn State College of Medicine researchers have developed a new technique that allows scientists to visualize every cell containing melanin pigment in 3D, in whole zebrafish.

6 Oct 2021

Pathology News and Research

Further Reading

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

Immune system activation is modulated according to the time of day

Researchers use game theory to understand how cells compete in tumors

Researchers illustrate the importance and value of sharing negative research results

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

Personality traits associated with hallmarks of Alzheimer’s disease

NYU Langone launches new center to advance scientific discovery and treatment of neurodegenerative diseases

CDC and ClinGen partner to develop expert curated variant list for the genomic community

Study investigates the link between gray matter and white matter neurodegeneration in subjective cognitive decline

Prior immunity to influenza, not SARS-CoV-2, prevents severe disease and mortality

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

NIH grant to benefit researcher's effort in developing a new method for detecting breast cancer

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

High fat diet exacerbates Alzheimer's disease in mouse model

University of Washington partners with USAID to better identify and prevent future pandemics

Novel technique enables 3D visualization of cells containing melanin pigment

Researchers identify mechanism that can lead to deafness in rare Norrie disease

Cancer drug can restore memory and cognitive function in mice with Alzheimer’s symptoms

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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