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New approach to vaccine development and improved surveillance could help target deadly diseases

Scientists hope that a new approach to vaccine development, combined with improved surveillance of potential future threats of outbreak, could help to massively reduce the impact of deadly diseases such as Ebola, Marburg and Lassa fever.

26 Sep 2018

Yellow fever virus can be transmitted via tiger mosquitoes, shows research

Since December 2016, Brazil has been grappling with its worst yellow fever outbreak for several decades. To date, there have been 2,043 human cases including 676 fatalities, mainly occurring in ten Brazilian states including Rio de Janeiro and São Paulo.

26 Sep 2018

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Metastatic tumors are characterized by a high degree of chromosomal instability--that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether chromosomal instability contributes to the metastatic process.

26 Sep 2018

RTI Surgical showcases innovative spine portfolio at NASS 2018

RTI Surgical, Inc., a global surgical implant company, will showcase research reinforcing the strength of its spine portfolio, notably the Fortilink IBF series featuring TETRAfuse 3D Technology, at the North American Spine Society's 33rd Annual Meeting in Los Angeles, September 26-29.

26 Sep 2018

Survey: Physicians need more information to assess impact of NSCLC treatment sequencing

Results from a new global survey revealed that more than one-third (36%) of the 310 physicians surveyed do not think they have sufficient information required to make informed decisions on how to sequence treatments for patients with epidermal growth factor receptor mutation-positive (EGFR M+) non-small cell lung cancer (NSCLC).

26 Sep 2018

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Japanese scientists have revealed a biological "switch" that influences whether an immature blood cell would develop into a red blood cell or a subtype of white blood cell called myeloid cells in response to infection or inflammation within the body.

26 Sep 2018

Exploring parallels between biological and computing world

RNA-based algorithms can advance cellular computing and enable new biological solutions for healthcare and industrial biotechnology.

26 Sep 2018

New approach for bone marrow transplant could make it safer and more effective for patients

Two recent studies in the journal Leukemia present a new approach for bone marrow donation and transplant that preclinical laboratory tests suggest could make the life-saving procedure safer and more effective for patients.

26 Sep 2018

New findings show importance of physical forces in tumor metastasis

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel.

26 Sep 2018

Researchers discover novel targeting agents to prevent cancer metastasis

Recently, a research team led by Maurizio Pellecchia at the University of California, Riverside, discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

26 Sep 2018

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Mesoblast Limited today announced that Mesoblast's proprietary allogeneic mesenchymal precursor cell heart failure product candidate MPC-150-IM for use in children with hypoplastic left heart syndrome was featured at the First Cardiac Regenerative Symposium for Congenital Heart Disease in Baltimore, Maryland on the weekend.

26 Sep 2018

Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer.

26 Sep 2018

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

Pathogenic bacteria hibernate to escape antibiotic treatments

BACTERIA University of Copenhagen researchers have discovered a surprising tactic of pathogenic bacteria when being attacked by antibiotics: hibernation.

26 Sep 2018

Study reveals structure of potential drug target in neurological conditions

Researchers at Van Andel Research Institute (VARI) have revealed the atomic-level structure of a protein that could serve as a promising new drug target for the treatment of neurological conditions such as bipolar disorder and Alzheimer’s disease.

25 Sep 2018

DFG establishes nine new Research Units

The Deutsche Forschungsgemeinschaft is establishing nine new Research Units, following a decision by the Senate and the Joint Committee in Bonn.

25 Sep 2018

New technology helps detect smallest magnetic fields produced in neuronal networks

The scientists in Freiburg will produce and optimize NV centers in diamond in order to achieve highly sensitive magnet field detectors working at room temperature, and by those means develop the world's first laser threshold magnetometer.

25 Sep 2018

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Following the closure of several research programs for Alzheimer's disease, in early 2018 the FDA issued a release entitled "Draft Guidance for Industry: Early Alzheimer's Disease: Developing Drugs for Treatment." Encouraged by the proposed changes in the new guidance, Genervon's research team reported new findings that its drug candidate GM6 attenuates Alzheimer's disease in an early AD transgenic APP mice model.

25 Sep 2018

Tomocube introduces new holotomography microscope for live cell imaging

A novel optical microscope utilizing diffraction tomography to generate 3D holographic images of unlabelled live cells is now available from Tomocube. Called HT-1, the new microscope delivers quantitative nanoscale, real-time, dynamic images of individual living cells quickly and simply without any sample preparation.

From Tomocube Inc. 25 Sep 2018

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Researchers from Karolinska Institutet and Kancera AB have developed a molecule that makes cancer cells sensitive to radiotherapy. In a study published in Nature Communications, the researchers describe a new way to block cancer cells' ability to repair their DNA and thus stop the survival of cancer cells.

25 Sep 2018

B Cell News and Research

New approach to vaccine development and improved surveillance could help target deadly diseases

Yellow fever virus can be transmitted via tiger mosquitoes, shows research

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

RTI Surgical showcases innovative spine portfolio at NASS 2018

Survey: Physicians need more information to assess impact of NSCLC treatment sequencing

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Exploring parallels between biological and computing world

New approach for bone marrow transplant could make it safer and more effective for patients

New findings show importance of physical forces in tumor metastasis

Researchers discover novel targeting agents to prevent cancer metastasis

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Pathogenic bacteria hibernate to escape antibiotic treatments

Study reveals structure of potential drug target in neurological conditions

DFG establishes nine new Research Units

New technology helps detect smallest magnetic fields produced in neuronal networks

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Tomocube introduces new holotomography microscope for live cell imaging

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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