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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Orlando Health researchers develop blood test that can detect signs of concussion in children

Researchers at Orlando Health have developed a blood test that can detect even the most subtle signs of a concussion in children, correctly identifying the presence of traumatic brain injuries 94 percent of the time in a recent study.

10 Nov 2015

Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and rare genetic metabolic disorders, today announced the first data from the dose-escalation portion of the ongoing Phase 1 study evaluating single agent AG-120, a first-in-class, oral, selective, potent inhibitor of mutant isocitrate dehydrogenase-1 (IDH1), in advanced solid tumors. The data are being presented today at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston. AG-120 is being developed in collaboration with Celgene.

9 Nov 2015

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Armaron Bio, a Melbourne-based drug development company focused on heart failure and other diseases, is pleased to announce that it has begun its Phase II clinical trial for NP202, its novel lead candidate drug for heart failure.

9 Nov 2015

Two genetic variants interact to alter the brain responses to high-calorie foods

For the first time, researchers have identified two genetic variants that interact to alter the brain responses to high-calorie foods, a tie that could aid in the development of targeted treatments for obesity and overweight. Researchers at Imperial College London led by Tony Goldstone, MD, PhD, of Consultant Endocrinologist, found that two gene variants - FTO and DRD2 - influenced activity in the brain reward system when looking at pictures of high-calorie foods.

6 Nov 2015

Sleep loss reduces insulin sensitivity, increases diabetes risk

A new study by the University of Colorado shows that the longer people are awake during the time their biological clock is telling them to sleep the worse their sensitivity to insulin, which is a precursor to diabetes.

6 Nov 2015

UM SOM Dean E. Albert Reece to be honored with 2015 David E. Rogers Award

The Association of American Medical Colleges announced today that University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA, will receive the 2015 David E. Rogers Award, which honors a medical school faculty member who has made major contributions to improving the health and health care of the American people. He will be presented the Award on November 8, 2015 at the AAMC's Annual Awards Event.

6 Nov 2015

Age-related differences in brain health vary with fitness level in older adults

A new study shows that age-related differences in brain health - specifically the strength of connections between different regions of the brain - vary with fitness level in older adults. The findings suggest that greater cardiorespiratory fitness - a measure of aerobic endurance - relates to stronger brain connections and likely improves long-term brain function in aging populations.

6 Nov 2015

Vanderbilt wins NIA grant to study effectiveness of nicotine patch in improving memory loss in older adults with MCI

Vanderbilt University Medical Center has received a $9.4 million grant from the National Institute on Aging to test the effectiveness of a transdermal nicotine patch in improving memory loss in older adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease.

6 Nov 2015

Researchers identify potential brain-based biomarker for depressive symptoms

Approximately half of individuals who experience a traumatic brain injury (TBI) experience depression within a year.

6 Nov 2015

Researchers discover potential solution for side effects of immunotherapy treatment for Alzheimer's

It is estimated that 46.8 million people worldwide are living with dementia, with Alzheimer's disease the most common form.

5 Nov 2015

Communication network makes astrocytomas more resistant to treatment

Astrocytomas are special type of brain tumours that are difficult to treat, because they do not respond to standard forms of treatment. One reason for this resistance could be their ability to form a communication network.

5 Nov 2015

Accuray announces installation of CyberKnife M6 and TomoTherapy Systems at FALP Cancer Institute in Chile

Accuray Incorporated announced today that the first CyberKnife M6 and TomoTherapy Systems in Chile are now installed at Fundacion Arturo Lopez Perez (FALP) Cancer Institute in Santiago, Chile. FALP is also the first hospital in Latin America to install both Accuray systems.

5 Nov 2015

UCSF research on mood disorders aims to advance understanding and treatment of depression

A gift of $20 million from the Ray and Dagmar Dolby Family Fund to the Department of Psychiatry at UC San Francisco will support research on mood disorders, aiming to rapidly advance the understanding and treatment of depression, bipolar disorder and related illnesses.

5 Nov 2015

Estrogen-like drug may not be beneficial to women with Alzheimer's dementia

An estrogen-like drug, raloxifene, has no demonstrated benefit on memory and thinking skills for women with dementia due to Alzheimer's disease, according to a study published in the November 4, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Nov 2015

Liquid biopsy provides physicians with up-to-date information about patient's cancer

A team of researchers, including scientists from the Translational Genomics Research Institute, has reported that analyzing circulating tumor DNA (ctDNA) can track how a patient's cancer evolves and responds to treatment.

5 Nov 2015

Harnessing the brain's immune system to combat Alzheimer's disease

A new study appearing in the Journal of Neuroinflammation suggests that the brain's immune system could potentially be harnessed to help clear the amyloid plaques that are a hallmark of Alzheimer's disease.

5 Nov 2015

Researchers successfully repair nerve cell damage in Alzheimer's dementia

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Müller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease.

5 Nov 2015

Scientists create supercharged blood cell that may heal major wounds, block inflammation

Faculty of Medicine scientists have created a "Franken-platelet" - a supercharged blood cell - that might be capable of healing major wounds, busting clots or blocking inflammation.

5 Nov 2015

Experts to gather at DOHaD congress to address challenges that impact health of children, adolescents

Over 600 experts from around the world will meet to address the many challenges that currently impact the health of mothers, babies in the womb, infants, children and adolescents at the Society for the Developmental Origins of Health and Disease congress, which will be held in Africa for the first time.

5 Nov 2015

Unwanted formation of blood vessels in the brain may cause intractable difficulties for Parkinson's disease patients

Unwanted formation of blood vessels (angiogenesis) in the brain is likely to be the cause of intractable walking and balance difficulties for people who suffer from Parkinson's disease. This conclusion is supported by new research from Lund University in Sweden.

5 Nov 2015

Brain News and Research

Further Reading

Orlando Health researchers develop blood test that can detect signs of concussion in children

Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Two genetic variants interact to alter the brain responses to high-calorie foods

Sleep loss reduces insulin sensitivity, increases diabetes risk

UM SOM Dean E. Albert Reece to be honored with 2015 David E. Rogers Award

Age-related differences in brain health vary with fitness level in older adults

Vanderbilt wins NIA grant to study effectiveness of nicotine patch in improving memory loss in older adults with MCI

Researchers identify potential brain-based biomarker for depressive symptoms

Researchers discover potential solution for side effects of immunotherapy treatment for Alzheimer's

Communication network makes astrocytomas more resistant to treatment

Accuray announces installation of CyberKnife M6 and TomoTherapy Systems at FALP Cancer Institute in Chile

UCSF research on mood disorders aims to advance understanding and treatment of depression

Estrogen-like drug may not be beneficial to women with Alzheimer's dementia

Liquid biopsy provides physicians with up-to-date information about patient's cancer

Harnessing the brain's immune system to combat Alzheimer's disease

Researchers successfully repair nerve cell damage in Alzheimer's dementia

Scientists create supercharged blood cell that may heal major wounds, block inflammation

Experts to gather at DOHaD congress to address challenges that impact health of children, adolescents

Unwanted formation of blood vessels in the brain may cause intractable difficulties for Parkinson's disease patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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