Therapeutics News and Research

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UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes.

11 Apr 2023

Using tiny bubbles to improve gene therapy

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging - requiring a new method.

11 Apr 2023

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

Isolating tumor-reactive blood cells to treat cancers

Adoptive cell therapy (ACT) has become a promising immunotherapy tool to help treat advanced melanoma.

10 Apr 2023

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates - bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Esther Bullitt, PhD, associate professor of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, was awarded $1.5 million from the National Institutes of Health that will go toward the purchase of a cryogenic electron microscope.

10 Apr 2023

Discovery may change the way people think about immune strategies

The human body is capable of creating a vast, diverse repertoire of antibodies - the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.

7 Apr 2023

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

Researchers evaluated the association between omega-3 polyunsaturated fatty acids intake, cognitive decay, and dementia.

7 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

Non-drug interventions for Alzheimer's disease result in better quality of life and also save money

While new drugs to treat Alzheimer's disease tend to receive the most public attention, many well-researched ways to care for people with dementia don't involve medication.

7 Apr 2023

Activation of adult-born neurons restores cognitive, affective function in Alzheimer’s mouse models

People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression.

6 Apr 2023

How nanomedicine is revolutionizing care for cardiovascular disease

Researchers review recent advancements in nanomedicine treatment options for cardiovascular disease.

6 Apr 2023

Injectable microtissue shows promise to improve neuromuscular recovery after peripheral nerve injuries

Researchers engineered the first injectable microtissue containing motor and sensory neurons encased in protective tissue, called tissue engineered neuromuscular interfaces (TE-NMIs).

6 Apr 2023

Researchers construct super-sized nanocage for delivering larger drug cargoes

Think about how frustrating it is to try to fit a gift into a box that is too small. Sometimes you just need a bigger box.

6 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

SFU researchers study pathogen genes to develop new drugs against bacterial infections

Researchers at Simon Fraser University are studying the genes of superbugs to aid the development of new and effective treatments for drug-resistant bacterial infections.

5 Apr 2023

Researchers develop a method for making “mini-heart” using pluripotent stem cells

A team at the Technical University of Munich has induced stem cells to emulate the development of the human heart.

5 Apr 2023

Naturally produced molecule directly targets and keeps Fusobacteria under control

Researchers at the Forsyth Institute have discovered an important mechanism that may have profound implications for how we prevent colorectal cancer. Oddly enough, their discovery began in the mouth.

5 Apr 2023

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Mosaic Therapeutics, an oncology therapeutics company dedicated to resolving cancer’s complexity to power new treatments for patients, today announced the close of its $28 million series A funding round.

From Mosaic Therapeutics 4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

Therapeutics News and Research

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Using tiny bubbles to improve gene therapy

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Isolating tumor-reactive blood cells to treat cancers

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Discovery may change the way people think about immune strategies

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Non-drug interventions for Alzheimer's disease result in better quality of life and also save money

Activation of adult-born neurons restores cognitive, affective function in Alzheimer’s mouse models

How nanomedicine is revolutionizing care for cardiovascular disease

Injectable microtissue shows promise to improve neuromuscular recovery after peripheral nerve injuries

Researchers construct super-sized nanocage for delivering larger drug cargoes

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

SFU researchers study pathogen genes to develop new drugs against bacterial infections

Researchers develop a method for making “mini-heart” using pluripotent stem cells

Naturally produced molecule directly targets and keeps Fusobacteria under control

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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