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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

SARS-CoV-2 infections on French mink farms after one year of COVID-19

A new paper, which appears on the bioRxiv* preprint server, describes the investigation of all French mink farms towards the end of 2020. This was to maximize the chances of identifying SARS-CoV-2 infection in these animals at any time over the past year.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers explore a mutational signature related to molnupiravir in SARS-CoV-2 sequencing datasets.

3 Feb 2023

New electrochemical sensing technology enables detection of SARS-CoV-2 antigen-specific antibodies

Not all SARS-CoV-2 infections are created equal. We have learned this through multiple virus waves are taking their toll on the world's population.

3 Feb 2023

New device identifies key membrane protein in urine that could be used to detect brain cancer

Researchers at Nagoya University in Japan have used a new device to identify a key membrane protein in urine that indicates whether the patient has a brain tumor.

2 Feb 2023

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Patients with glioblastoma - the deadliest type of primary brain tumor - may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

2 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Neutralizing antibodies to Toscana and Sandfly Fever Sicilian virus found in quails

The quail could be the unknown reservoir of the Toscana virus (TOSV) and the Sandfly Fever Sicilian virus (SFSV), mosquito-borne pathogens that can infect domestic animals and also cause disease in humans.

1 Feb 2023

Deep-learning based filter removes false positives, improves the accuracy of cancer diagnosis

Next-generation cancer strategies rely on next-generation gene sequencing (NGS), which paves the way for new techniques and tools to detect mutations and determine patient therapy.

1 Feb 2023

Highly effective detection of cancer biomarkers using CRISPR

Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms.

1 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

RNA News and Research

Further Reading

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

SARS-CoV-2 infections on French mink farms after one year of COVID-19

The relationship between natural plant extracts and SARS-CoV-2

Molnupiravir-related mutational signatures among COVID-19 patients

New electrochemical sensing technology enables detection of SARS-CoV-2 antigen-specific antibodies

New device identifies key membrane protein in urine that could be used to detect brain cancer

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Novel tool uses AI to predict the efficacy of genome-editing repair options

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

Researchers report a heterologous vaccination strategy against IBV in Chickens

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Neutralizing antibodies to Toscana and Sandfly Fever Sicilian virus found in quails

Deep-learning based filter removes false positives, improves the accuracy of cancer diagnosis

Highly effective detection of cancer biomarkers using CRISPR

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Study solves a 50-year mystery about messenger RNAs

Could novel lineages eventually dominate the viral population?

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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