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Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Company developing targeted oncology therapies spun out of world-leading research at the Wellcome Sanger Institute, in collaboration with the Netherlands Cancer Institute.

From Mosaic Therapeutics 4 Apr 2023

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease - about a half million people in the United States alone suffer from the condition.

4 Apr 2023

Updated booster shots vital for keeping COVID-19 in check

Between natural infection and a global vaccination campaign, most people now have some immunity against the virus that causes COVID-19.

3 Apr 2023

Mount Sinai to expand research training program in skin biology with support from $1.3 million T32 grant

The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai will expand its research training program in skin biology with support from a five-year, $1.3 million T32 grant from the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

3 Apr 2023

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Julia TCW, PhD, assistant professor of pharmacology & experimental therapeutics at Boston University Chobanian & Avedisian School of Medicine, has received a five-year, $3.9 million grant from the National Institutes of Health's National Institute on Aging.

3 Apr 2023

Long-term pancreatic cancer survivors’ microbiomes have increased levels of specific bacteria

Even as pancreatic cancer treatments improve, only about 9% of patients survive past five years. Researchers have searched unsuccessfully to find genetic differences that explain why some patients survive long term and some do not and have now shifted their focus to the gut microbiome.

3 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

3D Printing the Way to New Cancer Treatments

In this interview, we speak to Ishani Malhotra, CEO of Carcinotech, about their 3D-printed tumor replicas that are being used to better understand personalized cancer treatments.

3 Apr 2023

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

Therapeutics that use mRNA - like some of the COVID-19 vaccines - have enormous potential for the prevention and treatment of many diseases.

31 Mar 2023

Study shows a genetic association of diarrhea in children

Susceptibility to diarrhea, a major cause of infant deaths in low- and middle-income countries, has genetic links which could hold the key to new treatments, research suggests.

31 Mar 2023

Common amino acid discovery improves understanding of the biological causes of depression

A common amino acid, glycine, can deliver a "slow-down" signal to the brain, likely contributing to major depression, anxiety and other mood disorders in some people, scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have found.

30 Mar 2023

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

With the aid of a near $3.2 million National Cancer Institute grant (R01CA277599) recently awarded, investigators from the state's leading cancer program, Rutgers Cancer Institute of New Jersey,  and Georgetown University's Lombardi Comprehensive Cancer Center, both NCI-designated Comprehensive Cancer Centers, will work to close racial disparity gaps in cancer care delivery by examining a novel approach to genetic testing and care based on community-identified needs.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation - the transplantation of living cells, tissues and organs from one species to another - two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

AI tool highlights the need to improve diets in long-term care

A detailed analysis of consumed food showed there is a need to improve diets in long-term care (LTC) homes to make them healthier for residents.

29 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

People with asthma or eczema more likely to develop osteoarthritis

Stanford Medicine scientists and their colleagues have found that having asthma or eczema increases the likelihood of developing osteoarthritis — signaling that there may be an allergic pathway that can be targeted with existing drugs.

28 Mar 2023

Therapeutics News and Research

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Updated booster shots vital for keeping COVID-19 in check

Mount Sinai to expand research training program in skin biology with support from $1.3 million T32 grant

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Long-term pancreatic cancer survivors’ microbiomes have increased levels of specific bacteria

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

3D Printing the Way to New Cancer Treatments

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

Study shows a genetic association of diarrhea in children

Common amino acid discovery improves understanding of the biological causes of depression

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

Study shows how neutrophils play a key role in cancer immunotherapy success

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

New review examines link between HDLC and different types of cancer

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

AI tool highlights the need to improve diets in long-term care

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

People with asthma or eczema more likely to develop osteoarthritis

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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